Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

Àlex Bayés; Mark O. Collins; Mike D. R. Croning; Louie N. van de Lagemaat; Jyoti S. Choudhary; Seth G. N. Grant

doi:10.1371/journal.pone.0046683

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Research Article

Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

Àlex Bayés ,

* E-mail: seth.grant@ed.ac.uk (SG); ABayesP@santpau.cat (AB)

Affiliations Molecular Physiology of the Synapse Laboratory, Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, UAB, Barcelona, Catalonia, Spain, Genes to Cognition Programme, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridgeshire, United Kingdom, Department of Clinical Neuroscience. School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, United Kingdom
⨯
Mark O. Collins,

Affiliation Proteomic Mass Spectrometry, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom
⨯
Mike D. R. Croning,

Affiliations Genes to Cognition Programme, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridgeshire, United Kingdom, Department of Clinical Neuroscience. School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, United Kingdom
⨯
Louie N. van de Lagemaat,

Affiliations Genes to Cognition Programme, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridgeshire, United Kingdom, Department of Clinical Neuroscience. School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, United Kingdom
⨯
Jyoti S. Choudhary,

Affiliation Proteomic Mass Spectrometry, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom
⨯
Seth G. N. Grant

* E-mail: seth.grant@ed.ac.uk (SG); ABayesP@santpau.cat (AB)

Affiliations Genes to Cognition Programme, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridgeshire, United Kingdom, Department of Clinical Neuroscience. School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, United Kingdom
⨯

Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

Àlex Bayés,
Mark O. Collins,
Mike D. R. Croning,
Louie N. van de Lagemaat,
Jyoti S. Choudhary,
Seth G. N. Grant

Published: October 5, 2012
https://doi.org/10.1371/journal.pone.0046683

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