A Novel Antibody-Based Biomarker for Chronic Algal Toxin Exposure and Sub-Acute Neurotoxicity

Kathi A. Lefebvre; Elizabeth R. Frame; Frances Gulland; John D. Hansen; Preston S. Kendrick; Richard P. Beyer; Theo K. Bammler; Frederico M. Farin; Emma M. Hiolski; Donald R. Smith; David J. Marcinek

doi:10.1371/journal.pone.0036213

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Open Access

Peer-reviewed

Research Article

A Novel Antibody-Based Biomarker for Chronic Algal Toxin Exposure and Sub-Acute Neurotoxicity

Kathi A. Lefebvre ,

* E-mail: Kathi.Lefebvre@noaa.gov

Affiliation Exposure Assessment and Biomedical Models, Northwest Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America
⨯
Elizabeth R. Frame,

Affiliation Exposure Assessment and Biomedical Models, Northwest Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America
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Frances Gulland,

Affiliation The Marine Mammal Center, Sausalito, California, United States of America
⨯
John D. Hansen,

Affiliation U. S. Geological Survey-Western Fisheries Research Center, Seattle, Washington, United States of America
⨯
Preston S. Kendrick,

Affiliation Exposure Assessment and Biomedical Models, Northwest Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America
⨯
Richard P. Beyer,

Affiliation Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America
⨯
Theo K. Bammler,

Affiliation Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America
⨯
Frederico M. Farin,

Affiliation Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America
⨯
Emma M. Hiolski,

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Donald R. Smith,

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
David J. Marcinek

Affiliation Departments of Radiology and Bioengineering, University of Washington, Seattle, Washington, United States of America
⨯

A Novel Antibody-Based Biomarker for Chronic Algal Toxin Exposure and Sub-Acute Neurotoxicity

Kathi A. Lefebvre,
Elizabeth R. Frame,
Frances Gulland,
John D. Hansen,
Preston S. Kendrick,
Richard P. Beyer,
Theo K. Bammler,
Frederico M. Farin,
Emma M. Hiolski,
Donald R. Smith

Published: May 2, 2012
https://doi.org/10.1371/journal.pone.0036213

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04 May 2012
20:37 GMT
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Media Coverage of This Article Posted by PLOS_ONE_Group on 04 May 2012 at 20:37 GMT

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