Amplification by PCR Artificially Reduces the Proportion of the Rare Biosphere in Microbial Communities

• Juan M. Gonzalez ,

  * E-mail: jmgrau@irnase.csic.es

  Affiliation Institute of Natural Resources and Agrobiology, Spanish Council for Research, IRNAS-CSIC, Sevilla, Spain

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• Maria C. Portillo,

  Affiliation Institute of Natural Resources and Agrobiology, Spanish Council for Research, IRNAS-CSIC, Sevilla, Spain

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• Pedro Belda-Ferre,

  Affiliation Genomics and Health Department, Center for Advanced Research in Public Health (CSISP), Valencia, Spain

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• Alex Mira

  Affiliation Genomics and Health Department, Center for Advanced Research in Public Health (CSISP), Valencia, Spain

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