About the Authors

Baligh R. Yehia

byehia@upenn.edu

Affiliations Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

Asher J. Schranz

Affiliation Department of Medicine, New York University School of Medicine, New York, New York, United States of America

Craig A. Umscheid

Affiliations Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Evidenced-Based Practice, University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States of America

Vincent Lo Re III

Affiliations Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

Competing Interests

BRY receives investigator-initiated research support (to the University of Pennsylvania) from Gilead Sciences; AJS has no such interests; CAU has no such interests; VLR receives investigator-initiated research support (to the University of Pennsylvania) from AstraZeneca, Bristol Myers-Squibb, Merck, and Gilead Sciences. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: BRY AJS CAU VLR. Performed the experiments: BRY AJS CAU VLR. Analyzed the data: BRY AJS CAU VLR. Wrote the paper: BRY AJS CAU VLR.