A Novel Approach for Transcription Factor Analysis Using SELEX with High-Throughput Sequencing (TFAST)

Daniel J. Reiss; Frederick M. Howard; Harry L. T. Mobley

doi:10.1371/journal.pone.0042761

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Open Access

Peer-reviewed

Research Article

A Novel Approach for Transcription Factor Analysis Using SELEX with High-Throughput Sequencing (TFAST)

Daniel J. Reiss,

Affiliations Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Frederick M. Howard,

Affiliation University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Harry L. T. Mobley

* E-mail: hmobley@umich.edu

Affiliations Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯

A Novel Approach for Transcription Factor Analysis Using SELEX with High-Throughput Sequencing (TFAST)

Daniel J. Reiss,
Frederick M. Howard,
Harry L. T. Mobley

Published: August 3, 2012
https://doi.org/10.1371/journal.pone.0042761

About the Authors

Daniel J. Reiss

Affiliations Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

Frederick M. Howard

Affiliation University of Michigan Medical School, Ann Arbor, Michigan, United States of America

Harry L. T. Mobley

* E-mail: hmobley@umich.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DJR HLTM. Performed the experiments: DJR. Analyzed the data: DJR FMH. Contributed reagents/materials/analysis tools: DJR FMH. Wrote the paper: DJR HLTM.

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Sequence motif analysis
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Genomics
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Sequence alignment
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Transcription factors
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Binding analysis
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DNA-binding proteins
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DNA sequencing
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DNA libraries
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