About the Authors

Toshiyuki Fukada

Contributed equally to this work with: Toshiyuki Fukada, Natacha Civic, Tatsuya Furuichi

Affiliations Laboratory for Cytokine Signaling, RIKEN Research Center for Allergy and Immunology, Tsurumi, Yokohama, Kanagawa, Japan, Department of Allergy and Immunology, Osaka University Graduate School of Medicine, Osaka University, Osaka, Japan

Natacha Civic

Contributed equally to this work with: Toshiyuki Fukada, Natacha Civic, Tatsuya Furuichi

Affiliation Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland

Tatsuya Furuichi

Contributed equally to this work with: Toshiyuki Fukada, Natacha Civic, Tatsuya Furuichi

Affiliation Laboratory of Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, Minato-ku, Tokyo, Japan

Shinji Shimoda

Affiliation Department of Anatomy-1, Tsurumi University School of Dental Medicine, Tsurumi-ku, Yokohama, Kanagawa, Japan

Kenji Mishima

Affiliation Department of Pathology, Tsurumi University School of Dental Medicine, Tsurumi-ku, Yokohama, Kanagawa, Japan

Hiroyuki Higashiyama

Affiliation Department of Pathology, Tsurumi University School of Dental Medicine, Tsurumi-ku, Yokohama, Kanagawa, Japan

Yayoi Idaira

Affiliation Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, Tsurumi-ku, Yokohama, Kanagawa, Japan

Yoshinobu Asada

Affiliation Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, Tsurumi-ku, Yokohama, Kanagawa, Japan

Hiroshi Kitamura

Affiliation Laboratory for Immunogenomics, RIKEN Research Center for Allergy and Immunology, Tsurumi, Yokohama, Kanagawa, Japan

Satoru Yamasaki

Affiliation Laboratory for Cytokine Signaling, RIKEN Research Center for Allergy and Immunology, Tsurumi, Yokohama, Kanagawa, Japan

Shintaro Hojyo

Affiliations Laboratory for Cytokine Signaling, RIKEN Research Center for Allergy and Immunology, Tsurumi, Yokohama, Kanagawa, Japan, Department of Allergy and Immunology, Osaka University Graduate School of Medicine, Osaka University, Osaka, Japan

Manabu Nakayama

Affiliation Kazusa DNA Research Institute, Laboratory of Genome Technology, Kisarazu, Chiba, Japan

Osamu Ohara

Affiliations Laboratory for Immunogenomics, RIKEN Research Center for Allergy and Immunology, Tsurumi, Yokohama, Kanagawa, Japan, Kazusa DNA Research Institute, Laboratory of Genome Technology, Kisarazu, Chiba, Japan

Haruhiko Koseki

Affiliation Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Tsurumi, Yokohama, Kanagawa, Japan

Heloisa G. dos Santos

Affiliation Serviço de Genética Médica, Hospital S. Maria, Lisboa, Portugal

Luisa Bonafe

Affiliation Division of Molecular Pediatrics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Russia Ha-Vinh

Affiliation Division of Molecular Pediatrics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Andreas Zankl

Affiliation Division of Molecular Pediatrics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Sheila Unger

Affiliations Division of Molecular Pediatrics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, Department of Paediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany

Marius E. Kraenzlin

Affiliation Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital, Basel, Switzerland

Jacques S. Beckmann

Affiliations Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Ichiro Saito

Affiliation Department of Pathology, Tsurumi University School of Dental Medicine, Tsurumi-ku, Yokohama, Kanagawa, Japan

Carlo Rivolta

Affiliation Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland

Shiro Ikegawa

Affiliation Laboratory of Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, Minato-ku, Tokyo, Japan

Andrea Superti-Furga

asuperti@uniklinik-freiburg.de (AS-F); hirano@molonc.med.osaka-u.ac.jp (TH)

Affiliations Division of Molecular Pediatrics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, Department of Paediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany

Toshio Hirano

asuperti@uniklinik-freiburg.de (AS-F); hirano@molonc.med.osaka-u.ac.jp (TH)

Affiliations Laboratory for Cytokine Signaling, RIKEN Research Center for Allergy and Immunology, Tsurumi, Yokohama, Kanagawa, Japan, Laboratory of Developmental Immunology and the CREST Program of the Japan Science and Technology Agency, Graduate School of Frontier Biosciences, Graduate School of Medicine, and WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TF NC LB RHV AZ JB CR SI ASF TH. Performed the experiments: TF NC TF SS KM YI HK SY SH MN OO HK HGdS LB RHV AZ MEK CR. Analyzed the data: TF TF SS HH YA SY SH LB RHV AZ SU IS. Contributed reagents/materials/analysis tools: TF TF SS KM ASF. Wrote the paper: TF NC SU JB CR SI ASF TH. Joint Senior Authors: IS CR SI ASF TH.