A Novel RNA Transcript with Antiapoptotic Function Is Silenced in Fragile X Syndrome

Ahmad M. Khalil; Mohammad Ali Faghihi; Farzaneh Modarresi; Shaun P. Brothers; Claes Wahlestedt

doi:10.1371/journal.pone.0001486

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Open Access

Peer-reviewed

Research Article

A Novel RNA Transcript with Antiapoptotic Function Is Silenced in Fragile X Syndrome

Ahmad M. Khalil ,

Contributed equally to this work with: Ahmad M. Khalil, Mohammad Ali Faghihi

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida
⨯
Mohammad Ali Faghihi ,

Contributed equally to this work with: Ahmad M. Khalil, Mohammad Ali Faghihi

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida
⨯
Farzaneh Modarresi,

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida
⨯
Shaun P. Brothers,

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida
⨯
Claes Wahlestedt

*To whom correspondence should be addressed. E-mail: clawah@scripps.edu

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida
⨯

A Novel RNA Transcript with Antiapoptotic Function Is Silenced in Fragile X Syndrome

Ahmad M. Khalil,
Mohammad Ali Faghihi,
Farzaneh Modarresi,
Shaun P. Brothers,
Claes Wahlestedt

Published: January 23, 2008
https://doi.org/10.1371/journal.pone.0001486

About the Authors

Ahmad M. Khalil

Contributed equally to this work with: Ahmad M. Khalil, Mohammad Ali Faghihi

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida

Mohammad Ali Faghihi

Contributed equally to this work with: Ahmad M. Khalil, Mohammad Ali Faghihi

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida

Farzaneh Modarresi

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida

Shaun P. Brothers

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida

Claes Wahlestedt

*To whom correspondence should be addressed. E-mail: clawah@scripps.edu

Affiliation Molecular and Integrative Neurosciences Department (MIND), The Scripps Research Institute, Jupiter, Florida

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CW AK MF. Performed the experiments: AK MF FM SB. Analyzed the data: CW AK MF FM SB. Contributed reagents/materials/analysis tools: CW. Wrote the paper: CW AK MF.

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Small interfering RNA
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Transfection
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Cell proliferation
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Small nucleolar RNA
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Mammalian genomics
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RNA analysis
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