About the Authors
- Zi Di
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Affiliation Division of Toxicology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands
- Maarten J. D. Klop
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Affiliation OcellO B.V., Bio Partner Center Leiden, Leiden, The Netherlands
- Vasiliki-Maria Rogkoti
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Affiliation Division of Toxicology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands
- Sylvia E. Le Dévédec
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Affiliation Division of Toxicology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands
- Bob van de Water
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Affiliation Division of Toxicology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands
- Fons J. Verbeek
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Affiliation Imaging and BioInformatics, Leiden Institute of Advanced Computer Science, Leiden University, Leiden, The Netherlands
- Leo S. Price
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* E-mail: lsprice@lacdr.leidenuniv.nl
Affiliations Division of Toxicology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands, OcellO B.V., Bio Partner Center Leiden, Leiden, The Netherlands
- John H. N. Meerman
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Affiliation Division of Toxicology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands
Competing Interests
The authors have read the journal's policy and they have the following competing interests: Leo S Price is CSO, founder and majority shareholder of OcellO B.V. a spin-off from Leiden University that performs contract research compound testing on a fee-for-service basis. Maarten Klop is also an employee of OcellO B.V. Bob van de Water is a scientific advisor for OcellO B.V. and receives a fee for this role. These authors declare that this has in no way influenced the content or interpretation of data in the manuscript and that this does not alter their adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: ZD LSP JHNM BW FJV. Performed the experiments: ZD MJDK VMR SELD. Analyzed the data: ZD FJV JHNM LSP. Wrote the paper: ZD JHNM FJV LSP.