About the Authors

Debasish Sen

Affiliation Department of Physiology and Biophysics, University of California Irvine, Irvine, California, United States of America

Thomas J. Deerinck

Affiliation National Center for Microscopy and Imaging Research, Center for Research in Biological Structure and the Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

Mark H. Ellisman

Affiliation National Center for Microscopy and Imaging Research, Center for Research in Biological Structure and the Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

Ian Parker

Affiliations Department of Physiology and Biophysics, University of California Irvine, Irvine, California, United States of America, Department of Neurobiology and Behavior, University of California Irvine, Irvine, California, United States of America

Michael D. Cahalan

mcahalan@uci.edu

Affiliation Department of Physiology and Biophysics, University of California Irvine, Irvine, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DS MDC. Performed the experiments: DS. Analyzed the data: DS. Wrote the paper: DS MDC. Electron microscopy: TJD. Supervised electron microscopy: MHE. Supervised two-photon imaging: IP.