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Open Access

Peer-reviewed

Research Article

On State-Space Reduction in Multi-Strain Pathogen Models, with an Application to Antigenic Drift in Influenza A

  • Sergey Kryazhimskiy ,

    *To whom correspondence should be addressed. E-mail: skryazhi@princeton.edu

    Affiliation Program in Applied and Computational Mathematics, Princeton University, Princeton, New Jersey, United States of America

    ⨯
  • Ulf Dieckmann,

    Affiliation Evolution and Ecology Program, International Institute for Applied Systems Analysis, Laxenburg, Austria

    ⨯
  • Simon A Levin,

    Affiliation Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America

    ⨯
  • Jonathan Dushoff

    Affiliations Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America , Fogarty International Center, National Institute of Health, Bethesda, Maryland, United States of America

    ⨯

On State-Space Reduction in Multi-Strain Pathogen Models, with an Application to Antigenic Drift in Influenza A

  • Sergey Kryazhimskiy, 
  • Ulf Dieckmann, 
  • Simon A Levin, 
  • Jonathan Dushoff
PLOS
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  • Published: August 17, 2007
  • https://doi.org/10.1371/journal.pcbi.0030159
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  • Immunity  

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  • Influenza A virus  

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