Membrane Interaction of Bound Ligands Contributes to the Negative Binding Cooperativity of the EGF Receptor

• Anton Arkhipov,

  Affiliation D. E. Shaw Research, New York, New York, United States of America

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• Yibing Shan ,

  * E-mail: Yibing.Shan@DEShawResearch.com (YS); David.Shaw@DEShawResearch.com (DES)

  Affiliation D. E. Shaw Research, New York, New York, United States of America

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• Eric T. Kim,

  Affiliation D. E. Shaw Research, New York, New York, United States of America

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• David E. Shaw

  * E-mail: Yibing.Shan@DEShawResearch.com (YS); David.Shaw@DEShawResearch.com (DES)

  Affiliations D. E. Shaw Research, New York, New York, United States of America, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America

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