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OrganoID: A versatile deep learning platform for tracking and analysis of single-organoid dynamics

November 9, 2022

OrganoID: A versatile deep learning platform for tracking and analysis of single-organoid dynamics

Image credit: Matthews and Schuster et al pcbi.1010584

Recently Published Articles

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Current Issue October 2022

11/07/2022

Research Article

Probabilistic program inference in network-based epidemiological simulations

The ability to create computer simulations of epidemics is important to be able to predict where and when people will be become infected, identify factors which either contribute to or slow disease spread, and test various interventions without risking real lives. These researchers study methods for fitting parameters, such as infectiousness, to real world data so that the disease simulator correctly represents the actual disease.

Image credit: Smedemark-Margulies and Walters et al, pcbi.1010591

Probabilistic program inference in network-based epidemiological simulations

11/14/2022

Research Article

Adaptive multi-objective control explains how humans make lateral maneuvers while walking

In this new study, Desmet, Cusumano and Dingwell establish a theoretical basis for how humans make lateral maneuvers while walking, and their results demonstrate that humans might use evolving cost landscapes in real time to perform such an adaptive motor task and, furthermore, that such adaptation can occur quickly–over only one step.

Image credit: Desmet, Cusumano and Dingwell, pcbi.1010035

Adaptive multi-objective control explains how humans make lateral maneuvers while walking

11/02/2022

Research Article

Strength-dependent perturbation of whole-brain model working in different regimes reveals the role of fluctuations in brain dynamics

In this new study, Sanz Perl et al explored the question of how and why do complex, fluctuating, and oscillating dynamics characterise brain states? They showed that the fluctuations regime provides maximal flexibility to the human brain, a desirable property for brain dynamics to interact with the environment.

 Strength-dependent perturbation of whole-brain model working in different regimes reveals the role of fluctuations in brain dynamics

Image credit: Sanz Perl et al, pcbi.1010662

11/11/2021

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Diverse brain processing of sound localization in barn owls

Gorman et al investigated how neural connectivity and single-neuron computation may contribute to the emergence of spatial selectivity in auditory neurons in the barn owl's midbrain.

Diverse brain processing of sound localization in barn owls

Image credit: José Luis Peña

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PLOS Computational Biology | ISSN: 1553-7358 (online)