Achromobacter spp.: Emerging pathogens in the cystic fibrosis lung

Niladri Bhowmik, Reed M. Stubbendieck

PLOS Pathogens: published April 22, 2025 | https://doi.org/10.1371/journal.ppat.1013067

Staphylococcus aureus SspA (V8 protease): New skin pathogenesis insights into an old enzyme

John C. Thorstenson, Alexander R. Horswill

PLOS Pathogens: published April 24, 2025 | https://doi.org/10.1371/journal.ppat.1013048

Tailoring mRNA lipid nanoparticles for antifungal vaccines

Yeqi Li, Richard B. Meagher, Xiaorong Lin

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1013091

Pathogenic potential of polyextremotolerant fungi in a warming world

Erin C. Carr, Erin L. Bredeweg, Grace E. Hamilton, Tania Kurbessoian, Audrey M. Williams

PLOS Pathogens: published April 30, 2025 | https://doi.org/10.1371/journal.ppat.1013102

Phage therapy for Klebsiella pneumoniae: Understanding bacteria–phage interactions for therapeutic innovations

Julie Le Bris, Nathalie Chen, Adeline Supandy, Olaya Rendueles, Daria Van Tyne

PLOS Pathogens: published April 8, 2025 | https://doi.org/10.1371/journal.ppat.1012971

Influenza A virus RNA localisation and the interceding trafficking pathways of the host cell

Stefano Bonazza, David G. Courtney

PLOS Pathogens: published April 23, 2025 | https://doi.org/10.1371/journal.ppat.1013090

Leveraging microphysiological systems to expedite understanding of host–parasite interactions

Maria Zorrinho-Almeida, Jorge de-Carvalho, Maria Bernabeu, Sara Silva Pereira

PLOS Pathogens: published April 24, 2025 | https://doi.org/10.1371/journal.ppat.1013088

GS143, an inhibitor of E3 ligase β-TrCP, reverses HIV-1 latency without activating T cells via unconventional activation of NFκB

Srijata Sarkar, Yoshifumi Kobayashi, Timothy Russnak, Jing Shen, Ronald G. Nahass, Joseph P. Dougherty, Céline Gélinas

PLOS Pathogens: published April 1, 2025 | https://doi.org/10.1371/journal.ppat.1013018

DHX15 inhibits mouse APOBEC3 deamination

Wenming Zhao, Ayan Modak, Susan R. Ross

PLOS Pathogens: published April 1, 2025 | https://doi.org/10.1371/journal.ppat.1013045

Single-Cell Transcriptomic Analysis of Kaposi Sarcoma

Daniel A. Rauch, Paula Valiño Ramos, Mariam Khanfar, John Harding, Ancy Joseph, Anam Fahad, Paul Simonson, Isabel Risch, Obi Griffith, Malachi Griffith, Lee Ratner

PLOS Pathogens: published April 1, 2025 | https://doi.org/10.1371/journal.ppat.1012233

Heat shock protein 90 is a chaperone regulator of HIV-1 latency

Somaya Noorsaeed, Nawal AlBurtamani, Ahmed Rokan, Ariberto Fassati

PLOS Pathogens: published April 1, 2025 | https://doi.org/10.1371/journal.ppat.1012524

Salmonella Typhi serine threonine kinase T4519 induces lysosomal membrane permeabilization by manipulating Toll-like receptor 2-Cystatin B-Cathepsin B-NF-κB-reactive oxygen species pathway and promotes survival within human macrophages

Swarnali Chakraborty, Debayan Ganguli, Theeya Nagaraja, Animesh Gope, Sudip Dey, Ananda Pal, Rahul Shubhra Mandal, Sudipta Sekhar Das, Santasabuj Das

PLOS Pathogens: published April 1, 2025 | https://doi.org/10.1371/journal.ppat.1013041

ATP depletion in anthrax edema toxin pathogenesis

Jie Liu, Qing Cao, Michael Ewing, Zehua Zuo, Jason R. Kennerdell, Toren Finkel, Stephen H. Leppla, Shihui Liu

PLOS Pathogens: published April 1, 2025 | https://doi.org/10.1371/journal.ppat.1013017

Genetically distinct within-host subpopulations of hepatitis C virus persist after Direct-Acting Antiviral treatment failure

Lele Zhao, Matthew Hall, Prahalad Giridhar, Mahan Ghafari, Steven Kemp, Haiting Chai, Paul Klenerman, Eleanor Barnes, M. Azim Ansari, Katrina Lythgoe

PLOS Pathogens: published April 1, 2025 | https://doi.org/10.1371/journal.ppat.1012959

NbPIRIN promotes the protease activity of papain-like cysteine protease NbRD21 to inhibit Chinese wheat mosaic virus infection

Kaili Zhong, Gecheng Xu, Jingjing Shi, Peng Liu, Aizhu Tu, Mila Wu, Jiaqian Liu, Jianping Chen, Jian Yang

PLOS Pathogens: published April 2, 2025 | https://doi.org/10.1371/journal.ppat.1013037

ExoS effector in Pseudomonas aeruginosa Hyperactive Type III secretion system mutant promotes enhanced Plasma Membrane Rupture in Neutrophils

Arianna D. Reuven, Sarah Katzenell, Bethany W. Mwaura, James B. Bliska

PLOS Pathogens: published April 2, 2025 | https://doi.org/10.1371/journal.ppat.1013021

The evolution of antibiotic resistance in Europe, 1998–2019

Martin Emons, François Blanquart, Sonja Lehtinen

PLOS Pathogens: published April 3, 2025 | https://doi.org/10.1371/journal.ppat.1012945

Vibrio cholerae cytolysin induces pro-inflammatory and death signals through novel TLR assembly

Shraddha Gandhi, Sindhoora Puravankara, Anish Kumar Mondal, Aakanksha Chauhan, Shashi Prakash Yadav, Kausik Chattopadhyay, Arunika Mukhopadhaya

PLOS Pathogens: published April 4, 2025 | https://doi.org/10.1371/journal.ppat.1013033

Intact HIV DNA decays in children with and without complete viral load suppression

Daniel B Reeves, Morgan Litchford, Carolyn S Fish, Anna Farrell-Sherman, Makayla Poindexter, Nashwa Ahmed, Noah A J Cassidy, Jillian Neary, Dalton Wamalwa, Agnes Langat, Daisy Chebet, Hellen Moraa, Annukka A R Antar, Jennifer Slyker, Sarah Benki-Nugent, Lillian B Cohn, Joshua T Schiffer, Julie Overbaugh, Grace John-Stewart, Dara A Lehman

PLOS Pathogens: published April 4, 2025 | https://doi.org/10.1371/journal.ppat.1013003

Proximity interactome of alphavirus replicase component nsP3 includes proviral host factors eIF4G and AHNAK

Aditya Thiruvaiyaru, Sari Mattila, Mohammadreza Sadeghi, Krystyna Naumenko, Andres Merits, Markku Varjosalo, Tero Ahola

PLOS Pathogens: published April 7, 2025 | https://doi.org/10.1371/journal.ppat.1013050

ADAR1 p150 prevents HSV-1 from triggering PKR/eIF2α-mediated translational arrest and is required for efficient viral replication

Adwait Parchure, Mia Cesarec, Antonija Braut, Robert Kolman, Vlatka Ivanišević, Marina Čunko, Slađana Bursać, Richard de Reuver, Antonija J. Begonja, Umberto Rosani, Siniša Volarević, Jonathan Maelfait, Igor Jurak

PLOS Pathogens: published April 8, 2025 | https://doi.org/10.1371/journal.ppat.1012452

Chlamydial protease-like activity factor targets SLC7A11 for degradation to induce ferroptosis and facilitate progeny releases

Wentao Chen, Xin Su, Yuying Pan, Han Zhou, Yidan Gao, Xuemei Wang, Lijuan Jiang, Lihong Zeng, Qingqing Xu, Xueying Yu, Xiaona Yin, Zhanqin Feng, Bao Zhang, Wei Zhao, Yaohua Xue, Lingli Tang, Heping Zheng

PLOS Pathogens: published April 8, 2025 | https://doi.org/10.1371/journal.ppat.1013060

Capture of fusion-intermediate conformations of SARS-CoV-2 spike requires receptor binding and cleavage at either the S1/S2 or S2’ site

Sabrina Lusvarghi, Russell Vassell, Brittany Williams, Haseebullah Baha, Sabari Nath Neerukonda, Carol D. Weiss

PLOS Pathogens: published April 8, 2025 | https://doi.org/10.1371/journal.ppat.1012808

N6-methyladenosine modification of the subgroup J avian leukosis viral RNAs attenuates host innate immunity via MDA5 signaling

Mengmeng Yu, Li Zhang, Ying Wang, Suyan Wang, Yongzhen Liu, Peng Liu, Yuntong Chen, Ru Guo, Lingzhai Meng, Tao Zhang, Wenrui Fan, Xiaole Qi, Yulu Duan, Yanping Zhang, Hongyu Cui, Yulong Gao

PLOS Pathogens: published April 8, 2025 | https://doi.org/10.1371/journal.ppat.1013064

HOPS/CORVET tethering complexes are critical for endocytosis and protein trafficking to invasion related organelles in malaria parasites

Joëlle Paolo Mesén-Ramírez, Gwendolin Fuchs, Jonas Burmester, Guilherme B. Farias, Ana María Alape-Flores, Shamit Singla, Arne Alder, José Cubillán-Marín, Carolina Castro-Peña, Sarah Lemcke, Holger Sondermann, Mónica Prado, Tobias Spielmann, Danny Wilson, Tim-Wolf Gilberger

PLOS Pathogens: published April 8, 2025 | https://doi.org/10.1371/journal.ppat.1013053

Identification of the Pseudomonas aeruginosa AgtR-CspC-RsaL pathway that controls Las quorum sensing in response to metabolic perturbation and Staphylococcus aureus

Junze Qu, Liwen Yin, Shanhua Qin, Xiaomeng Sun, Xuetao Gong, Shouyi Li, Xiaolei Pan, Yongxin Jin, Zhihui Cheng, Shouguang Jin, Weihui Wu

PLOS Pathogens: published April 8, 2025 | https://doi.org/10.1371/journal.ppat.1013054

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1. Correction: Identification of the Pseudomonas aeruginosa AgtR-CspC-RsaL pathway that controls Las quorum sensing in response to metabolic perturbation and Staphylococcus aureus

A targeted CRISPR screen identifies ETS1 as a regulator of HIV-1 latency

Manickam Ashokkumar, Terry L. Hafer, Abby Felton, Nancie M. Archin, David M. Margolis, Michael Emerman, Edward P. Browne

PLOS Pathogens: published April 8, 2025 | https://doi.org/10.1371/journal.ppat.1012467

A positive-sense single-stranded RNA virus acquired a negative-sense open reading frame through recombination

Xuan Dong, Fan Zhang, Yiting Wang, Cixiu Li, Xuan Li, Chengyan Zhou, Guohao Wang, Zhongshuai Tian, Jing Gao, Hu Zhou, Liying Sui, Hans Nauwynck, Patrick Sorgeloos, Edward C. Holmes, Jie Huang, Weifeng Shi

PLOS Pathogens: published April 8, 2025 | https://doi.org/10.1371/journal.ppat.1013015

Genome-wide analysis of fitness determinants of Staphylococcus aureus during growth in milk

Marita Torrissen Mårli, Anne Olsdatter Ohren Nordraak, Vincent de Bakker, Anja Ruud Winther, Xue Liu, Jan-Willem Veening, Davide Porcellato, Morten Kjos

PLOS Pathogens: published April 9, 2025 | https://doi.org/10.1371/journal.ppat.1013080

Fusaric acid-mediated S-glutathionylation of MaAKT1 channel confers the virulence of Foc TR4 to banana

Jun Zhang, Siwen Liu, Wenlong Yang, Yanling Xie, Chuange Shao, Zhi-Ren Zhang, Chunyu Li, Xiaoqiang Yao

PLOS Pathogens: published April 9, 2025 | https://doi.org/10.1371/journal.ppat.1013066

The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle

Arwa A. A. Faizo, Clare Bellward, Hegel R. Hernandez-Lopez, Andrew Stevenson, Quan Gu, Sheila V. Graham

PLOS Pathogens: published April 9, 2025 | https://doi.org/10.1371/journal.ppat.1012697

Live-cell RNA imaging with the inactivated endonuclease Csy4 enables new insights into plant virus transport through plasmodesmata

David Burnett, Mohamed Hussein, Zoe Kathleen Barr, Laura Newsha Näther, Kathryn M. Wright, Jens Tilsner

PLOS Pathogens: published April 9, 2025 | https://doi.org/10.1371/journal.ppat.1013049

Diversification of an emerging bacterial plant pathogen; insights into the global spread of Xanthomonas euvesicatoria pv. perforans

Sujan Timilsina, Fernanda Iruegas-Bocardo, Mustafa O. Jibrin, Anuj Sharma, Aastha Subedi, Amandeep Kaur, Gerald V. Minsavage, Jose C. Huguet-Tapia, Jeannie Klein-Gordon, Pragya Adhikari, Tika B. Adhikari, Gabriella Cirvilleri, Laura Belen Tapia de la Barrera, Eduardo Bernal, Tom C. Creswell, Tien Thi Kieu Doan, Teresa A. Coutinho, Daniel S. Egel, Rubén Félix-Gastélum, David M. Francis, Misrak Kebede, Melanie Lewis Ivey, Frank J. Louws, Laixin Luo, Elizabeth T. Maynard, Sally A. Miller, Nga Thi Thu Nguyen, Ebrahim Osdaghi, Alice M. Quezado-Duval, Rebecca Roach, Francesca Rotondo, Gail E. Ruhl, Vou M. Shutt, Petcharat Thummabenjapone, Cheryl Trueman, Pamela D. Roberts, Jeffrey B. Jones, Gary E. Vallad, Erica M. Goss

PLOS Pathogens: published April 9, 2025 | https://doi.org/10.1371/journal.ppat.1013036

IL-6 trans-signaling mediates cytokine secretion and barrier dysfunction in hantavirus-infected cells and correlates to severity in HFRS

Kimia T. Maleki, Linda Niemetz, Wanda Christ, Julia Wigren Byström, Therese Thunberg, Clas Ahlm, Jonas Klingström

PLOS Pathogens: published April 9, 2025 | https://doi.org/10.1371/journal.ppat.1013042

The dual functions of the GTPase BipA in ribosome assembly and surface structure biogenesis in Salmonella enterica serovar Typhimurium

Eunsil Choi, Eunwoo Ryu, Donghwee Kim, Ji-Won Byun, Kahyun Kim, Minho Lee, Jihwan Hwang

PLOS Pathogens: published April 9, 2025 | https://doi.org/10.1371/journal.ppat.1013047

Modularization of the type II secretion gene cluster from Xanthomonas euvesicatoria facilitates the identification of a structurally conserved XpsCLM assembly platform complex

Samuel Goll, Patrick Martin, Sylvestre Marillonnet, Daniela Büttner

PLOS Pathogens: published April 9, 2025 | https://doi.org/10.1371/journal.ppat.1013008

Disrupting the OTUD4-USP7 deubiquitinase complex to suppress herpesvirus replication: a novel antiviral strategy

Shaowei Wang, Xuezhang Tian, Yunhong Zhong, Xiaoyu Xie, Ming Gao, Chuchu Zhang, Xi Cheng, Yining Qi, Bo Zhong, Pinghui Feng, Ke Lan, Junjie Zhang

PLOS Pathogens: published April 10, 2025 | https://doi.org/10.1371/journal.ppat.1013052

Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus

Kerry McGowen, Tobias Funck, Xin Wang, Samuel Zinga, Ian D. Wolf, Chidiebere Akusobi, Claudia M. Denkinger, Eric J. Rubin, Mark R. Sullivan

PLOS Pathogens: published April 10, 2025 | https://doi.org/10.1371/journal.ppat.1013027

Mystique, a broad host range Acinetobacter phage, reveals the impact of culturing conditions on phage isolation and infectivity

Ellinor O Alseth, Carli Roush, Iris Irby, Mykhailo Kopylov, Daija Bobe, Monneh W Diggs, Kristy Nguyen, Huaijin Xu, Ingeborg Schmidt-Krey, Anton V Bryksin, Philip N Rather

PLOS Pathogens: published April 10, 2025 | https://doi.org/10.1371/journal.ppat.1012986

Structural basis and mode of action for two broadly neutralizing nanobodies targeting the highly conserved spike stem-helix of sarbecoviruses including SARS-CoV-2 and its variants

Liyan Guo, Zimin Chen, Sheng Lin, Fanli Yang, Jing Yang, Lingling Wang, Xindan Zhang, Xin Yuan, Bin He, Yu Cao, Jian Li, Qi Zhao, Guangwen Lu

PLOS Pathogens: published April 11, 2025 | https://doi.org/10.1371/journal.ppat.1013034

An anticipatory mechanism enhances the cooperative behaviors of quorum sensing mutants in Pseudomonas aeruginosa

Min Yuan, Huifang Qiu, Xiaoqing Zhou, Weijun Dai

PLOS Pathogens: published April 15, 2025 | https://doi.org/10.1371/journal.ppat.1013046

Listeria monocytogenes requires phosphotransferase systems to facilitate intracellular growth and virulence

Matthew J. Freeman, Noah J. Eral, John-Demian Sauer

PLOS Pathogens: published April 15, 2025 | https://doi.org/10.1371/journal.ppat.1012492

Gut commensal bacterium Bacteroides vulgatus exacerbates helminth-induced cardiac fibrosis through succinate accumulation

Jiaqi Wang, Jiali Yin, Xiaolei Liu, Yi Liu, Xuemin Jin

PLOS Pathogens: published April 16, 2025 | https://doi.org/10.1371/journal.ppat.1013069

Expansion of myeloid suppressor cells and suppression of Lassa virus-specific T cells during fatal Lassa fever

Blaise Lafoux, Gustave Fourcaud, Jimmy Hortion, Laura Soyer, Alexandra Journeaux, Clara Germain, Stéphanie Reynard, Hadrien Cousseau, Clémentine Larignon, Natalia Pietrosemoli, Séverine Croze, Joël Lachuer, Emeline Perthame, Sylvain Baize

PLOS Pathogens: published April 17, 2025 | https://doi.org/10.1371/journal.ppat.1013111

HIV-associated penile anaerobes disrupt epithelial barrier integrity

Lane B. Buchanan, Zhongtian Shao, Ronald M. Galiwango, Shirley Constable, David Zuanazzi, Victoria Menya Biribawa, Henry Rogers Ssemunywa, Annemarie Namuniina, Brenda Okech, Gabriella Edfeldt, Annelie Tjernlund, Aaron A. R. Tobian, Daniel E. Park, Tony Pham, Maliha Aziz, Juan E. Salazar, Sydney Nelson, Cindy M. Liu, Rupert Kaul, Jessica L. Prodger

PLOS Pathogens: published April 17, 2025 | https://doi.org/10.1371/journal.ppat.1013094

Heat shock factor 2 regulates oncogenic gamma-herpesvirus gene expression by remodeling the chromatin at the ORF50 and BZLF1 promoter

Lorenza Cutrone, Hedvig Djupenström, Jasmin Peltonen, Elena Martinez Klimova, Simona Corso, Silvia Giordano, Lea Sistonen, Silvia Gramolelli

PLOS Pathogens: published April 17, 2025 | https://doi.org/10.1371/journal.ppat.1013108

RNF149 modulates the type I IFN innate antiviral immune responses through degrading IRF3

Mengyun Wu, Jiamin Cai, Guodong Qiao, Xiaoping Li, Ji Zhou, Fei Xu, Yunfei Ye, Yufeng Wang, Xuena Xu, Jiaoyang Li, Xiaoyu Tian, Yu Shao, Chunsheng Dong, Zhengrong Chen, Chuangli Hao, Yi Yang, Jinping Zhang

PLOS Pathogens: published April 17, 2025 | https://doi.org/10.1371/journal.ppat.1013051

Activity-based protein profiling reveals both canonical and novel ubiquitin pathway enzymes in Plasmodium

Cameron Smith, Mohsen Hajisadeghian, Gerbrand J. van der Heden van Noort, Michael J. Deery, Adán Pinto-Fernández, Benedikt M. Kessler, Katerina Artavanis-Tsakonas

PLOS Pathogens: published April 18, 2025 | https://doi.org/10.1371/journal.ppat.1013032

Expanding kinetoplastid genome annotation through protein structure comparison

Juan Manuel Trinidad-Barnech, José Sotelo-Silveira, Darío Fernández Do Porto, Pablo Smircich

PLOS Pathogens: published April 21, 2025 | https://doi.org/10.1371/journal.ppat.1013120

Viral piracy of host RNA phosphatase DUSP11 by avipoxviruses

Kayla H. Szymanik, Emily A. Rex, Vamshikrishna R. Pothireddy, Don B. Gammon, Dustin C. Hancks, Christopher S. Sullivan

PLOS Pathogens: published April 21, 2025 | https://doi.org/10.1371/journal.ppat.1013101

The molecular basis for DNA-binding by competence T4P is distinct in a representative Gram-positive and Gram-negative species

Nicholas D. Christman, Ankur B. Dalia

PLOS Pathogens: published April 21, 2025 | https://doi.org/10.1371/journal.ppat.1013128

Intranasal parainfluenza virus-vectored vaccine expressing SARS-CoV-2 spike protein of Delta or Omicron B.1.1.529 induces mucosal and systemic immunity and protects hamsters against homologous and heterologous challenge

Hong-Su Park, Yumiko Matsuoka, Celia Santos, Cindy Luongo, Xueqiao Liu, Lijuan Yang, Jaclyn A. Kaiser, Eleanor F. Duncan, Reed F. Johnson, I-Ting Teng, Peter D. Kwong, Ursula J. Buchholz, Cyril Le Nouën

PLOS Pathogens: published April 21, 2025 | https://doi.org/10.1371/journal.ppat.1012585

RNA helicases, DDX5 and DDX17, facilitate lytic reactivation of gammaherpesviruses

Praneet Kaur Sandhu, Blossom Damania

PLOS Pathogens: published April 21, 2025 | https://doi.org/10.1371/journal.ppat.1013009

Mitochondrial hyperactivity and reactive oxygen species drive innate immunity to the yellow fever virus-17D live-attenuated vaccine

Samantha G. Muccilli, Benjamin Schwarz, Byron Shue, Forrest Jessop, Jeffrey G. Shannon, Charles L. Larson, Adam Hage, Seon-Hui Hong, Eric Bohrnsen, Thomas Hsu, Alison W. Ashbrook, Gail L. Sturdevant, Shelly J. Robertson, Joseph W. Guarnieri, Justin Lack, Douglas C. Wallace, Catharine M. Bosio, Margaret R. MacDonald, Charles M. Rice, Jonathan W. Yewdell, Sonja M. Best

PLOS Pathogens: published April 21, 2025 | https://doi.org/10.1371/journal.ppat.1012561

Quantifying prevalence and risk factors of HIV multiple infection in Uganda from population-based deep-sequence data

Michael A. Martin, Andrea Brizzi, Xiaoyue Xi, Ronald Moses Galiwango, Sikhulile Moyo, Deogratius Ssemwanga, Alexandra Blenkinsop, Andrew D. Redd, Lucie Abeler-Dörner, Christophe Fraser, Steven J. Reynolds, Thomas C. Quinn, Joseph Kagaayi, David Bonsall, David Serwadda, Gertrude Nakigozi, Godfrey Kigozi, M. Kate Grabowski, Oliver Ratmann, with the PANGEA-HIV Consortium and the Rakai Health Sciences Program

PLOS Pathogens: published April 22, 2025 | https://doi.org/10.1371/journal.ppat.1013065

Neuregulin-1 prevents death from a normally lethal respiratory viral infection

Syed-Rehan A. Hussain, Michelle Rohlfing, Jennifer Santoro, Phylip Chen, Kaushik Muralidharan, Matthew S. Bochter, Mark E. Peeples, Mitchell H. Grayson

PLOS Pathogens: published April 23, 2025 | https://doi.org/10.1371/journal.ppat.1013124

Lysosome and plasma membrane Piezo channels of Trypanosoma cruzi are essential for proliferation, differentiation and infectivity

Guozhong Huang, Mayara S. Bertolini, Justin Wiedeman, Ronald D. Etheridge, Teresa Cruz-Bustos, Roberto Docampo

PLOS Pathogens: published April 23, 2025 | https://doi.org/10.1371/journal.ppat.1013105

Vacuolar sterol β-glucosidase EGCrP2/Sgl1 deficiency in Cryptococcus neoformans: Dysfunctional autophagy and Mincle-dependent immune activation as targets of novel antifungal strategies

Takashi Watanabe, Masayoshi Nagai, Yohei Ishibashi, Mio Iwasaki, Masaki Mizoguchi, Masahiro Nagata, Takashi Imai, Koichi Takato, Akihiro Imamura, Yoshimitsu Kakuta, Takamasa Teramoto, Motohiro Tani, Junko Matsuda, Hideharu Ishida, Sho Yamasaki, Nozomu Okino, Makoto Ito

PLOS Pathogens: published April 24, 2025 | https://doi.org/10.1371/journal.ppat.1013089

Evolution of Escherichia coli strains under competent or compromised adaptive immunity

Camille Ameline, Elsa Seixas, Hugo C. Barreto, Nelson Frazão, Miguel V. Rodrigues, M. Rita Ventura, Marta Lourenço, Isabel Gordo

PLOS Pathogens: published April 24, 2025 | https://doi.org/10.1371/journal.ppat.1012442

Astrocyte-derived complement C3 facilitated microglial phagocytosis of synapses in Staphylococcus aureus-associated neurocognitive deficits

Haifang Zhang, Qiyuan Jin, Jijie Li, Jiali Wang, Mengqi Li, Qiao Yin, Qi Li, Yuwan Qi, Lingling Feng, Liang Shen, Yuan Qin, Qifei Cong

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1013126

The Emerging Fungal Pathogen Candida auris Induces IFNγ to Colonize the Skin

Diprasom Das, Shrihari M. Ganesh, Abtar Mishra, Mihai G. Netea, Shankar Thangamani

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1013114

In depth sequencing of a serially sampled household cohort reveals the within-host dynamics of Omicron SARS-CoV-2 and rare selection of novel spike variants

Emily E. Bendall, Derek Dimcheff, Leigh Papalambros, William J. Fitzsimmons, Yuwei Zhu, Jonathan Schmitz, Natasha Halasa, James Chappell, Emily T. Martin, Jessica E. Biddle, Sarah E. Smith-Jeffcoat, Melissa A. Rolfes, Alexandra Mellis, H. Keipp Talbot, Carlos Grijalva, Adam S. Lauring

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1013134

Variable rates of SARS-CoV-2 evolution in chronic infections

Ewan W. Smith, William L. Hamilton, Ben Warne, Elena R. Walker, Aminu S. Jahun, Myra Hosmillo, ISARIC Consortium, Ravindra K. Gupta, Ian Goodfellow, Effrossyni Gkrania-Klotsas, M. Estée Török, Christopher J. R. Illingworth

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1013109

EV-D68 cleaves LARP1 and PABPC1 by 3C^pro to redirect host mRNA translation machinery toward its genomic RNA

Ruyang Tan, Yuling Zhang, Mengqian Huang, Honghua Chen, Zixiang Liu, Zining Wang, Xiaoyan Li, Tao Wang, Zhiyun Wang

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1013098

HIV-1 cell-to-cell infection of macrophages escapes type I interferon and host restriction factors, and is resistant to antiretroviral drugs

Marie Woottum, Sen Yan, Agathe Durringer, Léa Mézière, Lucie Bracq, Mingyu Han, Delphine Ndiaye-Lobry, Julie Chaumeil, Jean-Christophe Pagès, Serge Benichou

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1013130

Regulation of diel locomotor activity and retinal responses of Anopheles stephensi by ingested histamine and serotonin is temperature- and infection-dependent

Kevin O. Ochwedo, Xiaodi Wang, Nora Céspedes, Ronald E. Bentil, Ryan Wild, Emily Hernandez, Amy Hernandez, Hannah L. Kaylor, Yared Debebe, Jyotishka Datta, Michael A. Robert, Jeffrey A. Riffell, Edwin E. Lewis, Shirley Luckhart

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1013139

Deposition of complement regulators on the surface of Plasmodium falciparum merozoites depends on the immune status of the host

Maria Rosaria Bassi, Bogdan Cristinoi, Frank Buitenwerf, Mark Bergholt Cuadrado, Kasper Haldrup Björnsson, Melanie Rose Walker, Frederica Dedo Partey, Andrew B. Ward, Michael Fokuo Ofori, Lea Barfod

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1013107

ves1α genes expression is the major determinant of Babesia bovis-infected erythrocytes cytoadhesion to endothelial cells

Hassan Hakimi, Junya Yamagishi, Miako Sakaguchi, Atefeh Fathi, Jae Seung Lee, Guilherme G. Verocai, Shin-ichiro Kawazu, Masahito Asada

PLOS Pathogens: published April 28, 2025 | https://doi.org/10.1371/journal.ppat.1012583

Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling

Alexis Audibert, Xavier Mas-Orea, Léa Rey, Marcy Belloy, Emilie Bassot, Louise Battut, Gilles Marodon, Frederick Masson, Matteo Serino, Nicolas Cenac, Gilles Dietrich, Chrystelle Bonnart, Nicolas Blanchard

PLOS Pathogens: published April 29, 2025 | https://doi.org/10.1371/journal.ppat.1013106

Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP

Franziska Solger, Jonas Rauch, Simone Vormittag, Mingzhen Fan, Lyudmil Raykov, Paul Charki, Ana Katic, François Letourneur, Thierry Soldati, Jürgen Seibel, Hubert Hilbi

PLOS Pathogens: published April 29, 2025 | https://doi.org/10.1371/journal.ppat.1013026

Rice stripe mosaic virus M protein antagonizes G-protein-induced antiviral autophagy in insect vectors

Ruonan Zhang, Tengfei Wang, Yu Cheng, Jiaxin Qiu, Dongsheng Jia, Hongyan Chen, Taiyun Wei, Xiao-Feng Zhang

PLOS Pathogens: published April 29, 2025 | https://doi.org/10.1371/journal.ppat.1013070

Correction: Long noncoding RNA MARL regulates antiviral responses through suppression miR-122-dependent MAVS downregulation in lower vertebrates

The PLOS Pathogens Editors

PLOS Pathogens: published April 7, 2025 | https://doi.org/10.1371/journal.ppat.1013059

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1. Long noncoding RNA MARL regulates antiviral responses through suppression miR-122-dependent MAVS downregulation in lower vertebrates

Correction: Circular RNA circDtx1 regulates IRF3-mediated antiviral immune responses through suppression of miR-15a-5p-dependent TRIF downregulation in teleost fish

The PLOS Pathogens Editors

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