PGRS domain structures: Doomed to sail the mycomembrane

Rita Berisio, Giovanni Delogu

PLOS Pathogens: published September 1, 2022 | https://doi.org/10.1371/journal.ppat.1010760

Can live-attenuated SARS-CoV-2 vaccine contribute to stopping the pandemic?

Patrick Chun Hean Tang, Wern Hann Ng, Nicholas J. C. King, Suresh Mahalingam

PLOS Pathogens: published September 21, 2022 | https://doi.org/10.1371/journal.ppat.1010821

Many ways, one microorganism: Several approaches to study Malassezia in interactions with model hosts

Kevin Ehemann, María Juliana Mantilla, Felipe Mora-Restrepo, Andrea Rios-Navarro, Maritza Torres, Adriana Marcela Celis Ramírez

PLOS Pathogens: published September 8, 2022 | https://doi.org/10.1371/journal.ppat.1010784

Modeling Candida auris skin colonization: Mice, swine, and humans

Emily F. Eix, Jeniel E. Nett

PLOS Pathogens: published September 8, 2022 | https://doi.org/10.1371/journal.ppat.1010730

Human monkeypox: A review of the literature

Rozana El Eid, Fatima Allaw, Sara F. Haddad, Souha S. Kanj

PLOS Pathogens: published September 22, 2022 | https://doi.org/10.1371/journal.ppat.1010768

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Uncontained spread of Fusarium wilt of banana threatens African food security

Anouk C. van Westerhoven, Harold J. G. Meijer, Michael F. Seidl, Gert H. J. Kema

PLOS Pathogens: published September 22, 2022 | https://doi.org/10.1371/journal.ppat.1010769

The emergence and worldwide spread of the species Trichophyton indotineae causing difficult-to-treat dermatophytosis: A new challenge in the management of dermatophytosis

Anuradha Chowdhary, Ashutosh Singh, Amtoj Kaur, Ananta Khurana

PLOS Pathogens: published September 29, 2022 | https://doi.org/10.1371/journal.ppat.1010795

After the virus has cleared—Can preclinical models be employed for Long COVID research?

Ethan B. Jansen, Spencer N. Orvold, Cynthia L. Swan, Anthony Yourkowski, Brittany M. Thivierge, Magen E. Francis, Anni Ge, Melissa Rioux, Joseph Darbellay, John G. Howland, Alyson A. Kelvin

PLOS Pathogens: published September 7, 2022 | https://doi.org/10.1371/journal.ppat.1010741

Advances in understanding red blood cell modifications by Babesia

Hassan Hakimi, Junya Yamagishi, Shin-ichiro Kawazu, Masahito Asada

PLOS Pathogens: published September 15, 2022 | https://doi.org/10.1371/journal.ppat.1010770

A conserved viral amphipathic helix governs the replication site-specific membrane association

Preethi Sathanantham, Wenhao Zhao, Guijuan He, Austin Murray, Emma Fenech, Arturo Diaz, Maya Schuldiner, Xiaofeng Wang

PLOS Pathogens: published September 1, 2022 | https://doi.org/10.1371/journal.ppat.1010752

Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies

Cathrine Scheepers, Prudence Kgagudi, Nonkululeko Mzindle, Elin S. Gray, Thandeka Moyo-Gwete, Bronwen E. Lambson, Brent Oosthuysen, Batsirai Mabvakure, Nigel J. Garrett, Salim S. Abdool Karim, Lynn Morris, Penny L. Moore

PLOS Pathogens: published September 2, 2022 | https://doi.org/10.1371/journal.ppat.1010450

Pre-exposure to mRNA-LNP inhibits adaptive immune responses and alters innate immune fitness in an inheritable fashion

Zhen Qin, Aurélie Bouteau, Christopher Herbst, Botond Z. Igyártó

PLOS Pathogens: published September 2, 2022 | https://doi.org/10.1371/journal.ppat.1010830

Lipocalin-2 is an essential component of the innate immune response to Acinetobacter baumannii infection

Jessica R. Sheldon, Lauren E. Himmel, Dillon E. Kunkle, Andrew J. Monteith, K. Nichole Maloney, Eric P. Skaar

PLOS Pathogens: published September 2, 2022 | https://doi.org/10.1371/journal.ppat.1010809

Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model

Peter A. C. Wing, Maria Prange-Barczynska, Amy Cross, Stefania Crotta, Claudia Orbegozo Rubio, Xiaotong Cheng, James M. Harris, Xiaodong Zhuang, Rachel L. Johnson, Kathryn A. Ryan, Yper Hall, Miles W. Carroll, Fadi Issa, Peter Balfe, Andreas Wack, Tammie Bishop, Francisco J. Salguero, Jane A. McKeating

PLOS Pathogens: published September 6, 2022 | https://doi.org/10.1371/journal.ppat.1010807

Evolution of functional antibodies following acute Epstein-Barr virus infection

Christina B. Karsten, Yannic C. Bartsch, Sally A. Shin, Matthew D. Slein, Howard M. Heller, Kumaran Kolandaivelu, Jaap M. Middeldorp, Galit Alter, Boris Julg

PLOS Pathogens: published September 6, 2022 | https://doi.org/10.1371/journal.ppat.1010738

Components of the LINC and NPC complexes coordinately target and translocate a virus into the nucleus to promote infection

Chelsey C. Spriggs, Grace Cha, Jiaqian Li, Billy Tsai

PLOS Pathogens: published September 6, 2022 | https://doi.org/10.1371/journal.ppat.1010824

Microglial STAT1-sufficiency is required for resistance to toxoplasmic encephalitis

Maureen N. Cowan, Michael A. Kovacs, Ish Sethi, Isaac W. Babcock, Katherine Still, Samantha J. Batista, Carleigh A. O’Brien, Jeremy A. Thompson, Lydia A. Sibley, Sydney A. Labuzan, Tajie H. Harris

PLOS Pathogens: published September 6, 2022 | https://doi.org/10.1371/journal.ppat.1010637

Biosynthetic proteins targeting the SARS-CoV-2 spike as anti-virals

Stéphanie Thébault, Nathalie Lejal, Alexis Dogliani, Amélie Donchet, Agathe Urvoas, Marie Valerio-Lepiniec, Muriel Lavie, Cécile Baronti, Franck Touret, Bruno Da Costa, Clara Bourgon, Audrey Fraysse, Audrey Saint-Albin-Deliot, Jessica Morel, Bernard Klonjkowski, Xavier de Lamballerie, Jean Dubuisson, Alain Roussel, Philippe Minard, Sophie Le Poder, Nicolas Meunier, Bernard Delmas

PLOS Pathogens: published September 6, 2022 | https://doi.org/10.1371/journal.ppat.1010799

Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin during interspecies competition

Jun Jie Wong, Foo Kiong Ho, Pei Yi Choo, Kelvin K. L. Chong, Chee Meng Benjamin Ho, Ramesh Neelakandan, Damien Keogh, Timothy Barkham, John Chen, Chuan Fa Liu, Kimberly A. Kline

PLOS Pathogens: published September 6, 2022 | https://doi.org/10.1371/journal.ppat.1010766

Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes

Emily Yang, Serina Huang, Yasaman Jami-Alahmadi, Gerald M. McInerney, James A. Wohlschlegel, Melody M. H. Li

PLOS Pathogens: published September 6, 2022 | https://doi.org/10.1371/journal.ppat.1010743

White spot syndrome virus directly activates mTORC1 signaling to facilitate its replication via polymeric immunoglobulin receptor-mediated infection in shrimp

Pan-Pan Hong, Cang Li, Guo-Juan Niu, Xiao-Fan Zhao, Jin-Xing Wang

PLOS Pathogens: published September 6, 2022 | https://doi.org/10.1371/journal.ppat.1010808

Enzymatic independent role of sphingosine kinase 2 in regulating the expression of type I interferon during influenza A virus infection

Mengqiong Xu, Sisi Xia, Mei Wang, Xiaolian Liu, Xin Li, Weijie Chen, Yaohao Wang, Hongjian Li, Chuan Xia, Jun Chen, Jianguo Wu

PLOS Pathogens: published September 7, 2022 | https://doi.org/10.1371/journal.ppat.1010794

Arbovirus-vector protein interactomics identifies Loquacious as a co-factor for dengue virus replication in Aedes mosquitoes

Benoit Besson, Oscar M. Lezcano, Gijs J. Overheul, Kirsten Janssen, Cornelia G. Spruijt, Michiel Vermeulen, Jieqiong Qu, Ronald P. van Rij

PLOS Pathogens: published September 8, 2022 | https://doi.org/10.1371/journal.ppat.1010329

Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods

Jennifer A. White, Joshua T. Kufera, Niklas Bachmann, Weiwei Dai, Francesco R. Simonetti, Ciara Armstrong, Jun Lai, Subul Beg, Janet D. Siliciano, Robert F. Siliciano

PLOS Pathogens: published September 8, 2022 | https://doi.org/10.1371/journal.ppat.1010845

TREX (transcription/export)-NP complex exerts a dual effect on regulating polymerase activity and replication of influenza A virus

Lingcai Zhao, Qingzheng Liu, Jingjin Huang, Yuanlu Lu, Yongzhen Zhao, Jihui Ping

PLOS Pathogens: published September 9, 2022 | https://doi.org/10.1371/journal.ppat.1010835

Extracellular vesicles derived from PPRV-infected cells enhance signaling lymphocyte activation molecular (SLAM) receptor expression and facilitate virus infection

Yan Chen, Ting Wang, Yang Yang, Yuan Fang, Bao Zhao, Wei Zeng, Daiyue Lv, Leyan Zhang, Yanming Zhang, Qinghong Xue, Xiwen Chen, Jingyu Wang, Xuefeng Qi

PLOS Pathogens: published September 9, 2022 | https://doi.org/10.1371/journal.ppat.1010759

The inclusion membrane protein IncS is critical for initiation of the Chlamydia intracellular developmental cycle

María Eugenia Cortina, R. Clayton Bishop, Brittany A. DeVasure, Isabelle Coppens, Isabelle Derré

PLOS Pathogens: published September 9, 2022 | https://doi.org/10.1371/journal.ppat.1010818

Lipopolysaccharide -mediated resistance to host antimicrobial peptides and hemocyte-derived reactive-oxygen species are the major Providencia alcalifaciens virulence factors in Drosophila melanogaster

Maria Shaka, Aranzazu Arias-Rojas, Alexandra Hrdina, Dagmar Frahm, Igor Iatsenko

PLOS Pathogens: published September 9, 2022 | https://doi.org/10.1371/journal.ppat.1010825

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

Marius Walter, Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam, Jennifer M. Hayashi, Andrew Cruz, Samah Shah, Frank W. Soveg, John D. Gross, Nevan J. Krogan, Keith R. Jerome, Birgit Schilling, Melanie Ott, Eric Verdin

PLOS Pathogens: published September 12, 2022 | https://doi.org/10.1371/journal.ppat.1010811

Infectious viral shedding of SARS-CoV-2 Delta following vaccination: A longitudinal cohort study

Miguel Garcia-Knight, Khamal Anglin, Michel Tassetto, Scott Lu, Amethyst Zhang, Sarah A. Goldberg, Adam Catching, Michelle C. Davidson, Joshua R. Shak, Mariela Romero, Jesus Pineda-Ramirez, Ruth Diaz-Sanchez, Paulina Rugart, Kevin Donohue, Jonathan Massachi, Hannah M. Sans, Manuella Djomaleu, Sujata Mathur, Venice Servellita, David McIlwain, Brice Gaudiliere, Jessica Chen, Enrique O. Martinez, Jacqueline M. Tavs, Grace Bronstone, Jacob Weiss, John T. Watson, Melissa Briggs-Hagen, Glen R. Abedi, George W. Rutherford, Steven G. Deeks, Charles Chiu, Sharon Saydah, Michael J. Peluso, Claire M. Midgley, Jeffrey N. Martin, Raul Andino, J. Daniel Kelly

PLOS Pathogens: published September 12, 2022 | https://doi.org/10.1371/journal.ppat.1010802

Localized cardiolipin synthesis is required for the assembly of MreB during the polarized cell division of Chlamydia trachomatis

Scot P. Ouellette, Laura A. Fisher-Marvin, McKenna Harpring, Junghoon Lee, Elizabeth A. Rucks, John V. Cox

PLOS Pathogens: published September 12, 2022 | https://doi.org/10.1371/journal.ppat.1010836

Novel viral splicing events and open reading frames revealed by long-read direct RNA sequencing of adenovirus transcripts

Alexander M. Price, Robert T. Steinbock, Richard Lauman, Matthew Charman, Katharina E. Hayer, Namrata Kumar, Edwin Halko, Krystal K. Lum, Monica Wei, Angus C. Wilson, Benjamin A. Garcia, Daniel P. Depledge, Matthew D. Weitzman

PLOS Pathogens: published September 12, 2022 | https://doi.org/10.1371/journal.ppat.1010797

Reovirus uses temporospatial compartmentalization to orchestrate core versus outercapsid assembly

Justine Kniert, Theodore dos Santos, Heather E. Eaton, Woo Jung Cho, Greg Plummer, Maya Shmulevitz

PLOS Pathogens: published September 13, 2022 | https://doi.org/10.1371/journal.ppat.1010641

Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages

Steven J. Conrad, Tahseen Raza, Erich A. Peterson, Jason Liem, Richard Connor, Bernice Nounamo, Martin Cannon, Jia Liu

PLOS Pathogens: published September 14, 2022 | https://doi.org/10.1371/journal.ppat.1010316

GAPDH mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites

Andrew J. Jezewski, Ann M. Guggisberg, Dana M. Hodge, Naomi Ghebremichael, Gavin Nicholas John, Lisa K. McLellan, Audrey Ragan Odom John

PLOS Pathogens: published September 14, 2022 | https://doi.org/10.1371/journal.ppat.1010803

Strengthening of enterococcal biofilms by Esp

Lindsey Spiegelman, Adrian Bahn-Suh, Elizabeth T. Montaño, Ling Zhang, Greg L. Hura, Kathryn A. Patras, Amit Kumar, F. Akif Tezcan, Victor Nizet, Susan E. Tsutakawa, Partho Ghosh

PLOS Pathogens: published September 14, 2022 | https://doi.org/10.1371/journal.ppat.1010829

Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917

Ilia Gelfat, Yousuf Aqeel, Jacqueline M. Tremblay, Justyna J. Jaskiewicz, Anishma Shrestha, James N. Lee, Shenglan Hu, Xi Qian, Loranne Magoun, Abhineet Sheoran, Daniela Bedenice, Colter Giem, Avinash Manjula-Basavanna, Amanda R. Pulsifer, Hann X. Tu, Xiaoli Li, Marilyn L. Minus, Marcia S. Osburne, Saul Tzipori, Charles B. Shoemaker, John M. Leong, Neel S. Joshi

PLOS Pathogens: published September 15, 2022 | https://doi.org/10.1371/journal.ppat.1010713

A tRNA-derived fragment present in E. coli OMVs regulates host cell gene expression and proliferation

Idrissa Diallo, Jeffrey Ho, Marine Lambert, Abderrahim Benmoussa, Zeinab Husseini, David Lalaouna, Eric Massé, Patrick Provost

PLOS Pathogens: published September 15, 2022 | https://doi.org/10.1371/journal.ppat.1010827

Vimentin inhibits α-tubulin acetylation via enhancing α-TAT1 degradation to suppress the replication of human parainfluenza virus type 3

Pengfei Liu, Shengwei Zhang, Jingyi Ma, Dongning Jin, Yali Qin, Mingzhou Chen

PLOS Pathogens: published September 15, 2022 | https://doi.org/10.1371/journal.ppat.1010856

SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice

Sherif A. El-Kafrawy, Abby Odle, Aymn T. Abbas, Ahmed M. Hassan, Umama A. Abdel-dayem, Arooj K. Qureshi, Lok-Yin Roy Wong, Jian Zheng, David K. Meyerholz, Stanley Perlman, Alimuddin Zumla, Esam I. Azhar

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010782

Multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS

Richa Batra, William Whalen, Sergio Alvarez-Mulett, Luis G. Gomez-Escobar, Katherine L. Hoffman, Will Simmons, John Harrington, Kelsey Chetnik, Mustafa Buyukozkan, Elisa Benedetti, Mary E. Choi, Karsten Suhre, Edward Schenck, Augustine M. K. Choi, Frank Schmidt, Soo Jung Cho, Jan Krumsiek

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010819

Thiopurines inhibit coronavirus Spike protein processing and incorporation into progeny virions

Eric S. Pringle, Brett A. Duguay, Maxwell P. Bui-Marinos, Rory P. Mulloy, Shelby L. Landreth, Krishna Swaroop Desireddy, Stacia M. Dolliver, Shan Ying, Taylor Caddell, Trinity H. Tooley, Patrick D. Slaine, Stephen L. Bearne, Darryl Falzarano, Jennifer A. Corcoran, Denys A. Khaperskyy, Craig McCormick

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010832

The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors

Ravi F. Iyer, David M. Edwards, Philipp Kolb, Hans-Peter Raué, Chris A. Nelson, Megan L. Epperson, Mark K. Slifka, Jeffrey C. Nolz, Hartmut Hengel, Daved H. Fremont, Klaus Früh

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010783

A remodeled RNA polymerase II complex catalyzing viroid RNA-templated transcription

Shachinthaka D. Dissanayaka Mudiyanselage, Junfei Ma, Tibor Pechan, Olga Pechanova, Bin Liu, Ying Wang

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010850

RIPK3 and caspase 8 collaborate to limit herpes simplex encephalitis

Hongyan Guo, Heather S. Koehler, Edward S. Mocarski, Richard D. Dix

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010857

Metabolic flexibilities and vulnerabilities in the pentose phosphate pathway of the zoonotic pathogen Toxoplasma gondii

Ningbo Xia, Xuefang Guo, Qinghong Guo, Nishith Gupta, Nuo Ji, Bang Shen, Lihua Xiao, Yaoyu Feng

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010864

Genome-wide association study of leprosy in Malawi and Mali

James J. Gilchrist, Kathryn Auckland, Tom Parks, Alexander J. Mentzer, Lily Goldblatt, Vivek Naranbhai, Gavin Band, Kirk A. Rockett, Ousmane B. Toure, Salimata Konate, Sibiri Sissoko, Abdoulaye A. Djimdé, Mahamadou A. Thera, Ogobara K. Doumbo, Samba Sow, Sian Floyd, Jörg M. Pönnighaus, David K. Warndorff, Amelia C. Crampin, Paul E. M. Fine, Benjamin P. Fairfax, Adrian V. S. Hill

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010312

Progranulin aggravates lethal Candida albicans sepsis by regulating inflammatory response and antifungal immunity

Jiayu Liu, Xiaofei Lai, Renlin Yu, Hao Ding, Haobo Bai, Zhubin Yang, Yibing Yin, Fang Xu, Ju Cao

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010873

Beneficial effects of cellular coinfection resolve inefficiency in influenza A virus transcription

Jessica R. Shartouny, Chung-Young Lee, Gabrielle K. Delima, Anice C. Lowen

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010865

Characterization of dengue virus 3’UTR RNA binding proteins in mosquitoes reveals that AeStaufen reduces subgenomic flaviviral RNA in saliva

Shih-Chia Yeh, Mayra Diosa-Toro, Wei-Lian Tan, Florian Rachenne, Arthur Hain, Celestia Pei Xuan Yeo, Inès Bribes, Benjamin Wong Wei Xiang, Gayathiri Sathiamoorthy Kannan, Menchie Casayuran Manuel, Dorothée Missé, Yu Keung Mok, Julien Pompon

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010427

Influenza A virus activates cellular Tropomyosin receptor kinase A (TrkA) signaling to promote viral replication and lung inflammation

Vikram Verma, Mythili Dileepan, Qinfeng Huang, Thu Phan, Wei-Shou Hu, Hinh Ly, Yuying Liang

PLOS Pathogens: published September 19, 2022 | https://doi.org/10.1371/journal.ppat.1010874

A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts

Julie-Anne Gabelich, Josephine Grützke, Florian Kirscht, Oliver Popp, Joachim M. Matz, Gunnar Dittmar, Melanie Rug, Alyssa Ingmundson

PLOS Pathogens: published September 20, 2022 | https://doi.org/10.1371/journal.ppat.1010846

MERS-CoV ORF4b is a virulence factor involved in the inflammatory pathology induced in the lungs of mice

Melissa Bello-Perez, Jesús Hurtado-Tamayo, Ricardo Requena-Platek, Javier Canton, Pedro José Sánchez-Cordón, Raúl Fernandez-Delgado, Luis Enjuanes, Isabel Sola

PLOS Pathogens: published September 21, 2022 | https://doi.org/10.1371/journal.ppat.1010834

Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster

Crystal M. Vincent, Esteban J. Beckwith, Carolina J. Simoes da Silva, William H. Pearson, Katrin Kierdorf, Giorgio F. Gilestro, Marc S. Dionne

PLOS Pathogens: published September 21, 2022 | https://doi.org/10.1371/journal.ppat.1010826

An ACE2-dependent Sarbecovirus in Russian bats is resistant to SARS-CoV-2 vaccines

Stephanie N. Seifert, Shuangyi Bai, Stephen Fawcett, Elizabeth B. Norton, Kevin J. Zwezdaryk, James Robinson, Bronwyn Gunn, Michael Letko

PLOS Pathogens: published September 22, 2022 | https://doi.org/10.1371/journal.ppat.1010828

Knockout of liver fluke granulin, Ov-grn-1, impedes malignant transformation during chronic infection with Opisthorchis viverrini

Sujittra Chaiyadet, Sirikachorn Tangkawattana, Michael J. Smout, Wannaporn Ittiprasert, Victoria H. Mann, Raksawan Deenonpoe, Patpicha Arunsan, Alex Loukas, Paul J. Brindley, Thewarach Laha

PLOS Pathogens: published September 22, 2022 | https://doi.org/10.1371/journal.ppat.1010839

Age-dependent virulence of human pathogens

Gabriele Sorci, Bruno Faivre

PLOS Pathogens: published September 22, 2022 | https://doi.org/10.1371/journal.ppat.1010866

Ecdysone signaling mediates the trade-off between immunity and reproduction via suppression of amyloids in the mosquito Aedes aegypti

Mao Wang, Yanhong Wang, Mengmeng Chang, Xueli Wang, Zuokun Shi, Alexander S. Raikhel, Zhen Zou

PLOS Pathogens: published September 22, 2022 | https://doi.org/10.1371/journal.ppat.1010837

Four layer multi-omics reveals molecular responses to aneuploidy in Leishmania

Bart Cuypers, Pieter Meysman, Ionas Erb, Wout Bittremieux, Dirk Valkenborg, Geert Baggerman, Inge Mertens, Shyam Sundar, Basudha Khanal, Cedric Notredame, Jean-Claude Dujardin, Malgorzata A. Domagalska, Kris Laukens

PLOS Pathogens: published September 23, 2022 | https://doi.org/10.1371/journal.ppat.1010848

Binding of adenovirus species C hexon to prothrombin and the influence of hexon on vector properties in vitro and in vivo

Jie Tian, Zhili Xu, Rituparna Moitra, Donna J. Palmer, Philip Ng, Andrew P. Byrnes

PLOS Pathogens: published September 26, 2022 | https://doi.org/10.1371/journal.ppat.1010859

Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution

Weiwen Liang, Timothy J. C. Tan, Yiquan Wang, Huibin Lv, Yuanxin Sun, Roberto Bruzzone, Chris K. P. Mok, Nicholas C. Wu

PLOS Pathogens: published September 26, 2022 | https://doi.org/10.1371/journal.ppat.1010875

Light chain 2 is a Tctex-type related axonemal dynein light chain that regulates directional ciliary motility in Trypanosoma brucei

Subash Godar, James Oristian, Valerie Hinsch, Katherine Wentworth, Ethan Lopez, Parastoo Amlashi, Gerald Enverso, Samantha Markley, Joshua Daniel Alper

PLOS Pathogens: published September 26, 2022 | https://doi.org/10.1371/journal.ppat.1009984

Mouse models of COVID-19 recapitulate inflammatory pathways rather than gene expression

Cameron R. Bishop, Troy Dumenil, Daniel J. Rawle, Thuy T. Le, Kexin Yan, Bing Tang, Gunter Hartel, Andreas Suhrbier

PLOS Pathogens: published September 26, 2022 | https://doi.org/10.1371/journal.ppat.1010867

Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole

Edar O. Pech-Santiago, Raúl Argüello-García, Citlali Vázquez, Emma Saavedra, Iliana González-Hernández, Helgi Jung-Cook, Steven P. Rafferty, M. Guadalupe Ortega-Pierres

PLOS Pathogens: published September 27, 2022 | https://doi.org/10.1371/journal.ppat.1010840

Rice apoplastic CBM1-interacting protein counters blast pathogen invasion by binding conserved carbohydrate binding module 1 motif of fungal proteins

Takumi Takeda, Machiko Takahashi, Motoki Shimizu, Yu Sugihara, Tetsuro Yamashita, Hiromasa Saitoh, Koki Fujisaki, Kazuya Ishikawa, Hiroe Utsushi, Eiko Kanzaki, Yuichi Sakamoto, Akira Abe, Ryohei Terauchi

PLOS Pathogens: published September 29, 2022 | https://doi.org/10.1371/journal.ppat.1010792

The capsule of Bacillus anthracis protects it from the bactericidal activity of human defensins and other cationic antimicrobial peptides

David K. O’Brien, Wilson J. Ribot, Donald J. Chabot, Angelo Scorpio, Steven A. Tobery, Tanya M. Jelacic, Zhibin Wu, Arthur M. Friedlander

PLOS Pathogens: published September 29, 2022 | https://doi.org/10.1371/journal.ppat.1010851

Rta is the principal activator of Epstein-Barr virus epithelial lytic transcription

Ahmed Ali, Makoto Ohashi, Alejandro Casco, Reza Djavadian, Mark Eichelberg, Shannon C. Kenney, Eric Johannsen

PLOS Pathogens: published September 29, 2022 | https://doi.org/10.1371/journal.ppat.1010886

Complex and simple translational readthrough signals in pea enation mosaic virus 1 and potato leafroll virus, respectively

Tamari Chkuaseli, K. Andrew White

PLOS Pathogens: published September 29, 2022 | https://doi.org/10.1371/journal.ppat.1010888

Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages

Allison Cohen, Edwin E. Jeng, Mark Voorhies, Jane Symington, Nebat Ali, Rosa A. Rodriguez, Michael C. Bassik, Anita Sil

PLOS Pathogens: published September 29, 2022 | https://doi.org/10.1371/journal.ppat.1010237

Shedding of infectious SARS-CoV-2 despite vaccination

Kasen K. Riemersma, Luis A. Haddock III, Nancy A. Wilson, Nicholas Minor, Jens Eickhoff, Brittany E. Grogan, Amanda Kita-Yarbro, Peter J. Halfmann, Hannah E. Segaloff, Anna Kocharian, Kelsey R. Florek, Ryan Westergaard, Allen Bateman, Gunnar E. Jeppson, Yoshihiro Kawaoka, David H. O’Connor, Thomas C. Friedrich, Katarina M. Grande

PLOS Pathogens: published September 30, 2022 | https://doi.org/10.1371/journal.ppat.1010876

Gene expression of axenically-isolated clinical Entamoeba histolytica strains and its impact on disease severity of amebiasis

Yasuaki Yanagawa, Shinji Izumiyama, Yumiko Saito-Nakano, Kumiko Nakada-Tsukui, Seiki Kobayashi, Naoko Yoshida, Yoshimi Kikuchi, Hiroyuki Gatanaga, Shinichi Oka, Tomoyoshi Nozaki, Koji Watanabe

PLOS Pathogens: published September 30, 2022 | https://doi.org/10.1371/journal.ppat.1010880

Formal Comment on “Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques” by Bochart et al. (2021)

Rudolf P. Bohm, Matthew W. Breed, Joyce K. Cohen, Andrew J. Haertel, Lisa C. Halliday, Joshua A. Kramer, Mia T. Lieberman, Kelly A. Rice, Jeffery A. Roberts, Kasi E. Russell-Logrigue, Gregory W. Salyards, Diana G. Scorpio, J. Scott Weese

PLOS Pathogens: published September 27, 2022 | https://doi.org/10.1371/journal.ppat.1010831