One Health: A new definition for a sustainable and healthy future

One Health High-Level Expert Panel (OHHLEP), Wiku B. Adisasmito, Salama Almuhairi, Casey Barton Behravesh, Pépé Bilivogui, Salome A. Bukachi, Natalia Casas, Natalia Cediel Becerra, Dominique F. Charron, Abhishek Chaudhary, Janice R. Ciacci Zanella, Andrew A. Cunningham, Osman Dar, Nitish Debnath, Baptiste Dungu, Elmoubasher Farag, George F. Gao, David T. S. Hayman, Margaret Khaitsa, Marion P. G. Koopmans, Catherine Machalaba, John S. Mackenzie, Wanda Markotter, Thomas C. Mettenleiter, Serge Morand, Vyacheslav Smolenskiy, Lei Zhou

PLOS Pathogens: published June 23, 2022 | https://doi.org/10.1371/journal.ppat.1010537

PARP14: A key ADP-ribosylating protein in host–virus interactions?

Srivatsan Parthasarathy, Anthony R. Fehr

PLOS Pathogens: published June 9, 2022 | https://doi.org/10.1371/journal.ppat.1010535

Fashionably late: Temporal regulation of HSV-1 late gene transcription

Joseph R. Heath, Jill A. Dembowski

PLOS Pathogens: published June 16, 2022 | https://doi.org/10.1371/journal.ppat.1010536

Pathogenic prion structures at high resolution

Byron Caughey, Heidi G. Standke, Efrosini Artikis, Forrest Hoyt, Allison Kraus

PLOS Pathogens: published June 30, 2022 | https://doi.org/10.1371/journal.ppat.1010594

Key questions on the epigenetics of herpes simplex virus latency

Abigail L. Whitford, Anna R. Cliffe

PLOS Pathogens: published June 30, 2022 | https://doi.org/10.1371/journal.ppat.1010587

Rationale of using the dual chemokine receptor CCR2/CCR5 inhibitor cenicriviroc for the treatment of COVID-19

Daniel Clark Files, Frank Tacke, Alexandra O’Sullivan, Patrick Dorr, William G. Ferguson, William G. Powderly

PLOS Pathogens: published June 24, 2022 | https://doi.org/10.1371/journal.ppat.1010547

Projecting the SARS-CoV-2 transition from pandemicity to endemicity: Epidemiological and immunological considerations

Lily E. Cohen, David J. Spiro, Cecile Viboud

PLOS Pathogens: published June 30, 2022 | https://doi.org/10.1371/journal.ppat.1010591

The nonstructural p17 protein of a fusogenic bat-borne reovirus regulates viral replication in virus species- and host-specific manners

Ryotaro Nouda, Takahiro Kawagishi, Yuta Kanai, Masayuki Shimojima, Masayuki Saijo, Yoshiharu Matsuura, Takeshi Kobayashi

PLOS Pathogens: published June 2, 2022 | https://doi.org/10.1371/journal.ppat.1010553

The small nonstructural protein NP1 of human bocavirus 1 directly interacts with Ku70 and RPA70 and facilitates viral DNA replication

Kang Ning, Zekun Wang, Fang Cheng, Ziying Yan, Jianming Qiu

PLOS Pathogens: published June 2, 2022 | https://doi.org/10.1371/journal.ppat.1010578

SAFA facilitates chromatin opening of immune genes through interacting with anti-viral host RNAs

Lili Cao, Yujie Luo, Xuefei Guo, Shengde Liu, Siji Li, Junhong Li, Zeming Zhang, Yingchi Zhao, Qiao Zhang, Feng Gao, Xiong Ji, Xiang Gao, Yunfei Li, Fuping You

PLOS Pathogens: published June 3, 2022 | https://doi.org/10.1371/journal.ppat.1010599

Longitudinal kinetics of RBD+ antibodies in COVID-19 recovered patients over 14 months

Tsuf Eyran, Anna Vaisman-Mentesh, David Taussig, Yael Dror, Ligal Aizik, Aya Kigel, Shai Rosenstein, Yael Bahar, Dor Ini, Ran Tur-Kaspa, Tatyana Kournos, Dana Marcoviciu, Dror Dicker, Yariv Wine

PLOS Pathogens: published June 3, 2022 | https://doi.org/10.1371/journal.ppat.1010569

Secretory glycoprotein NS1 plays a crucial role in the particle formation of flaviviruses

Tomokazu Tamura, Shiho Torii, Kentaro Kajiwara, Itsuki Anzai, Yoichiro Fujioka, Kisho Noda, Shuhei Taguwa, Yuhei Morioka, Rigel Suzuki, Yuzy Fauzyah, Chikako Ono, Yusuke Ohba, Masato Okada, Takasuke Fukuhara, Yoshiharu Matsuura

PLOS Pathogens: published June 3, 2022 | https://doi.org/10.1371/journal.ppat.1010593

PRMT5 epigenetically regulates the E3 ubiquitin ligase ITCH to influence lipid accumulation during mycobacterial infection

Salik Miskat Borbora, Raju S. Rajmani, Kithiganahalli Narayanaswamy Balaji

PLOS Pathogens: published June 3, 2022 | https://doi.org/10.1371/journal.ppat.1010095

Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice

Liaoxun Lu, Tianhan Li, Xinyu Feng, Zhilong Liu, Yang Liu, Tianzhu Chao, Yanrong Gu, Rong Huang, Fanghui Zhang, Le He, Binhui Zhou, Eryan Kong, Zhuangzhuang Liu, Xugang Wang, Zhijun Chen, Hui Wang, Marie Malissen, Bernard Malissen, Lichen Zhang, Yinming Liang

PLOS Pathogens: published June 6, 2022 | https://doi.org/10.1371/journal.ppat.1010596

The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication, but essential for the production of infectious virus

Joseph C. Ward, Lidia Lasecka-Dykes, Chris Neil, Oluwapelumi O. Adeyemi, Sarah Gold, Niall McLean-Pell, Caroline Wright, Morgan R. Herod, David Kealy, Emma Warner, Terry Jackson, Donald P. King, Tobias J. Tuthill, David J. Rowlands, Nicola J. Stonehouse

PLOS Pathogens: published June 6, 2022 | https://doi.org/10.1371/journal.ppat.1010589

Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes

Nela Klimova, Jana Holubova, Gaia Streparola, Jakub Tomala, Ludmila Brazdilova, Ondrej Stanek, Ladislav Bumba, Peter Sebo

PLOS Pathogens: published June 6, 2022 | https://doi.org/10.1371/journal.ppat.1010577

T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin

Birgitta Lindqvist, Bianca B. Jütte, Luca Love, Wlaa Assi, Julie Roux, Anders Sönnerborg, Tugsan Tezil, Eric Verdin, J. Peter Svensson

PLOS Pathogens: published June 6, 2022 | https://doi.org/10.1371/journal.ppat.1010555

Maintenance and dissemination of avian-origin influenza A virus within the northern Atlantic Flyway of North America

Diann J. Prosser, Jiani Chen, Christina A. Ahlstrom, Andrew B. Reeves, Rebecca L. Poulson, Jeffery D. Sullivan, Daniel McAuley, Carl R. Callahan, Peter C. McGowan, Justin Bahl, David E. Stallknecht, Andrew M. Ramey

PLOS Pathogens: published June 6, 2022 | https://doi.org/10.1371/journal.ppat.1010605

Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis

Bradley E. Hiller, Yongjun Yin, Yi-Chieh Perng, Ítalo de Araujo Castro, Lindsey E. Fox, Marissa C. Locke, Kristen J. Monte, Carolina B. López, David M. Ornitz, Deborah J. Lenschow

PLOS Pathogens: published June 8, 2022 | https://doi.org/10.1371/journal.ppat.1010228

A novel SNF2 ATPase complex in Trypanosoma brucei with a role in H2A.Z-mediated chromatin remodelling

Tim Vellmer, Laura Hartleb, Albert Fradera Sola, Susanne Kramer, Elisabeth Meyer-Natus, Falk Butter, Christian J. Janzen

PLOS Pathogens: published June 8, 2022 | https://doi.org/10.1371/journal.ppat.1010514

Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA

Elena S. Kim, Jun Zhou, Hu Zhang, Alexander Marchetti, Maarten van de Klundert, Dawei Cai, Xiaoyang Yu, Bidisha Mitra, Yuanjie Liu, Mu Wang, Ulrike Protzer, Haitao Guo

PLOS Pathogens: published June 9, 2022 | https://doi.org/10.1371/journal.ppat.1010576

Quantitative regulation of the thermal stability of enveloped virus vaccines by surface charge engineering to prevent the self-aggregation of attachment glycoproteins

Yu Shang, Li Li, Tengfei Zhang, Qingping Luo, Qingzhong Yu, Zhe Zeng, Lintao Li, Miaomiao Jia, Guoyi Tang, Sanlin Fan, Qin Lu, Wenting Zhang, Yuhan Xue, Hongling Wang, Wei Liu, Hongcai Wang, Rongrong Zhang, Chan Ding, Huabin Shao, Guoyuan Wen

PLOS Pathogens: published June 9, 2022 | https://doi.org/10.1371/journal.ppat.1010564

Lipases secreted by a gut bacterium inhibit arbovirus transmission in mosquitoes

Xi Yu, Liangqin Tong, Liming Zhang, Yun Yang, Xiaoping Xiao, Yibin Zhu, Penghua Wang, Gong Cheng

PLOS Pathogens: published June 9, 2022 | https://doi.org/10.1371/journal.ppat.1010552

A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice

Ryan J. Malonis, George I. Georgiev, Denise Haslwanter, Laura A. VanBlargan, Georgia Fallon, Olivia Vergnolle, Sean M. Cahill, Richard Harris, David Cowburn, Kartik Chandran, Michael S. Diamond, Jonathan R. Lai

PLOS Pathogens: published June 9, 2022 | https://doi.org/10.1371/journal.ppat.1010573

A small molecule that disrupts S. Typhimurium membrane voltage without cell lysis reduces bacterial colonization of mice

Jamie L. Dombach, Joaquin LJ Quintana, Samual C. Allgood, Toni A. Nagy, Daniel L. Gustafson, Corrella S. Detweiler

PLOS Pathogens: published June 10, 2022 | https://doi.org/10.1371/journal.ppat.1010606

Stress- and metabolic responses of Candida albicans require Tor1 kinase N-terminal HEAT repeats

Wanjun Qi, Maikel Acosta-Zaldivar, Peter R. Flanagan, Ning-Ning Liu, Niketa Jani, José F. Fierro, María T. Andrés, Gary P. Moran, Julia R. Köhler

PLOS Pathogens: published June 10, 2022 | https://doi.org/10.1371/journal.ppat.1010089

Using an antimalarial in mosquitoes overcomes Anopheles and Plasmodium resistance to malaria control strategies

Douglas G. Paton, Alexandra S. Probst, Erica Ma, Kelsey L. Adams, W. Robert Shaw, Naresh Singh, Selina Bopp, Sarah K. Volkman, Domombele F. S. Hien, Prislaure S. L. Paré, Rakiswendé S. Yerbanga, Abdoullaye Diabaté, Roch K. Dabiré, Thierry Lefèvre, Dyann F. Wirth, Flaminia Catteruccia

PLOS Pathogens: published June 10, 2022 | https://doi.org/10.1371/journal.ppat.1010609

Insight into mechanisms of pig lncRNA FUT3-AS1 regulating E. coli F18-bacterial diarrhea

Zhengchang Wu, Hairui Fan, Jian Jin, Song Gao, Ruihua Huang, Shenglong Wu, Wenbin Bao

PLOS Pathogens: published June 13, 2022 | https://doi.org/10.1371/journal.ppat.1010584

Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode

Roz Laing, Stephen R. Doyle, Jennifer McIntyre, Kirsty Maitland, Alison Morrison, David J. Bartley, Ray Kaplan, Umer Chaudhry, Neil Sargison, Andy Tait, James A. Cotton, Collette Britton, Eileen Devaney

PLOS Pathogens: published June 13, 2022 | https://doi.org/10.1371/journal.ppat.1010545

On the relationship between Pathogenic Potential and Infective Inoculum

Daniel F. Q. Smith, Arturo Casadevall

PLOS Pathogens: published June 13, 2022 | https://doi.org/10.1371/journal.ppat.1010484

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1. Correction: On the relationship between Pathogenic Potential and Infective Inoculum

Long-term persistence of viral RNA and inflammation in the CNS of macaques exposed to aerosolized Venezuelan equine encephalitis virus

Henry Ma, Joseph R. Albe, Theron Gilliland, Cynthia M. McMillen, Christina L. Gardner, Devin A. Boyles, Emily L. Cottle, Matthew D. Dunn, Jeneveve D. Lundy, Noah Salama, Katherine J. O’Malley, Ivona Pandrea, Tobias Teichert, Stacey Barrick, William B. Klimstra, Amy L. Hartman, Douglas S. Reed

PLOS Pathogens: published June 13, 2022 | https://doi.org/10.1371/journal.ppat.1009946

Bile acids promote the caveolae-associated entry of swine acute diarrhea syndrome coronavirus in porcine intestinal enteroids

Qi-Yue Yang, Yong-Le Yang, Yi-Xin Tang, Pan Qin, Gan Wang, Jin-Yan Xie, Shu-Xian Chen, Chan Ding, Yao-Wei Huang, Shu Jeffrey Zhu

PLOS Pathogens: published June 13, 2022 | https://doi.org/10.1371/journal.ppat.1010620

Significant role of host sialylated glycans in the infection and spread of severe acute respiratory syndrome coronavirus 2

Wakana Saso, Masako Yamasaki, Shin-ichi Nakakita, Shuetsu Fukushi, Kana Tsuchimoto, Noriyuki Watanabe, Nongluk Sriwilaijaroen, Osamu Kanie, Masamichi Muramatsu, Yoshimasa Takahashi, Tetsuro Matano, Makoto Takeda, Yasuo Suzuki, Koichi Watashi

PLOS Pathogens: published June 14, 2022 | https://doi.org/10.1371/journal.ppat.1010590

Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli

Steven J. Hancock, Alvin W. Lo, Thomas Ve, Christopher J. Day, Lendl Tan, Alejandra A. Mendez, Minh-Duy Phan, Nguyen Thi Khanh Nhu, Kate M. Peters, Amanda C. Richards, Brittany A. Fleming, Chyden Chang, Dalton H. Y. Ngu, Brian M. Forde, Thomas Haselhorst, Kelvin G. K. Goh, Scott A. Beatson, Michael P. Jennings, Matthew A. Mulvey, Bostjan Kobe, Mark A. Schembri

PLOS Pathogens: published June 14, 2022 | https://doi.org/10.1371/journal.ppat.1010582

RANBP2 and USP9x regulate nuclear import of adenovirus minor coat protein IIIa

Ashrafali M. Ismail, Amrita Saha, Ji S. Lee, David F. Painter, Yinghua Chen, Gurdeep Singh, Gabriela N. Condezo, James Chodosh, Carmen San Martín, Jaya Rajaiya

PLOS Pathogens: published June 16, 2022 | https://doi.org/10.1371/journal.ppat.1010588

Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4

Hugh C. Welles, Hannah A. D. King, Leonard Nettey, Nicole Cavett, Jason Gorman, Tongqing Zhou, Yaroslav Tsybovsky, Renguang Du, Kaimei Song, Richard Nguyen, David Ambrozak, Amy Ransier, Chaim A. Schramm, Nicole A. Doria-Rose, Adrienne E. Swanstrom, James A. Hoxie, Celia LaBranche, David C. Montefiori, Daniel C. Douek, Peter D. Kwong, John R. Mascola, Mario Roederer, Rosemarie D. Mason

PLOS Pathogens: published June 16, 2022 | https://doi.org/10.1371/journal.ppat.1010574

p166 links membrane and intramitochondrial modules of the trypanosomal tripartite attachment complex

Bernd Schimanski, Salome Aeschlimann, Philip Stettler, Sandro Käser, Maria Gomez-Fabra Gala, Julian Bender, Bettina Warscheid, F.-Nora Vögtle, André Schneider

PLOS Pathogens: published June 16, 2022 | https://doi.org/10.1371/journal.ppat.1010207

The Neisseria gonorrhoeae type IV pilus promotes resistance to hydrogen peroxide- and LL-37-mediated killing by modulating the availability of intracellular, labile iron

Linda I. Hu, Elizabeth A. Stohl, H Steven Seifert

PLOS Pathogens: published June 17, 2022 | https://doi.org/10.1371/journal.ppat.1010561

S-Nitrosylation of the virulence regulator AphB promotes Vibrio cholerae pathogenesis

Jiandong Chen, Hyuntae Byun, Qianxuan She, Zhi Liu, Karl-Gustav Ruggeberg, Qinqin Pu, I-Ji Jung, Dehao Zhu, Mary R. Brockett, Ansel Hsiao, Jun Zhu

PLOS Pathogens: published June 17, 2022 | https://doi.org/10.1371/journal.ppat.1010581

Host cell-dependent late entry step as determinant of hepatitis B virus infection

Xupeng Hong, Yuka Imamura Kawasawa, Stephan Menne, Jianming Hu

PLOS Pathogens: published June 17, 2022 | https://doi.org/10.1371/journal.ppat.1010633

A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection

Scott P. Lawrence, Samra E. Elser, Workineh Torben, Robert V. Blair, Bapi Pahar, Pyone P. Aye, Faith Schiro, Dawn Szeltner, Lara A. Doyle-Meyers, Beth S. Haggarty, Andrea P. O. Jordan, Josephine Romano, George J. Leslie, Xavier Alvarez, David H. O’Connor, Roger W. Wiseman, Christine M. Fennessey, Yuan Li, Michael Piatak Jr, Jeffrey D. Lifson, Celia C. LaBranche, Andrew A. Lackner, Brandon F. Keele, Nicholas J. Maness, Mark Marsh, James A. Hoxie

PLOS Pathogens: published June 17, 2022 | https://doi.org/10.1371/journal.ppat.1010507

Identification of NS2 determinants stimulating intrinsic HCV NS2 protease activity

Olaf Isken, Thomas Walther, Luis Wong-Dilworth, Dirk Rehders, Lars Redecke, Norbert Tautz

PLOS Pathogens: published June 21, 2022 | https://doi.org/10.1371/journal.ppat.1010644

Selective modulation of cell surface proteins during vaccinia infection: A resource for identifying viral immune evasion strategies

Delphine M. Depierreux, Arwen F. Altenburg, Lior Soday, Alice Fletcher-Etherington, Robin Antrobus, Brian J. Ferguson, Michael P. Weekes, Geoffrey L. Smith

PLOS Pathogens: published June 21, 2022 | https://doi.org/10.1371/journal.ppat.1010612

Fish female-biased gene cyp19a1a leads to female antiviral response attenuation between sexes by autophagic degradation of MITA

Long-Feng Lu, Jing-Yu Jiang, Wen-Xuan Du, Xue-Li Wang, Zhuo-Cong Li, Xiao-Yu Zhou, Can Zhang, Cheng-Yan Mou, Dan-Dan Chen, Zhi Li, Li Zhou, Jian-Fang Gui, Xi-Yin Li, Shun Li

PLOS Pathogens: published June 21, 2022 | https://doi.org/10.1371/journal.ppat.1010626

Impact of secondary TCR engagement on the heterogeneity of pathogen-specific CD8⁺ T cell response during acute and chronic toxoplasmosis

Lindsey A. Shallberg, Anthony T. Phan, David A. Christian, Joseph A. Perry, Breanne E. Haskins, Daniel P. Beiting, Tajie H. Harris, Anita A. Koshy, Christopher A. Hunter

PLOS Pathogens: published June 21, 2022 | https://doi.org/10.1371/journal.ppat.1010296

Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis

Bryan A. Johnson, Yiyang Zhou, Kumari G. Lokugamage, Michelle N. Vu, Nathen Bopp, Patricia A. Crocquet-Valdes, Birte Kalveram, Craig Schindewolf, Yang Liu, Dionna Scharton, Jessica A. Plante, Xuping Xie, Patricia Aguilar, Scott C. Weaver, Pei-Yong Shi, David H. Walker, Andrew L. Routh, Kenneth S. Plante, Vineet D. Menachery

PLOS Pathogens: published June 21, 2022 | https://doi.org/10.1371/journal.ppat.1010627

Encapsulation of the septal cell wall protects Streptococcus pneumoniae from its major peptidoglycan hydrolase and host defenses

Joana Figueiredo, Mafalda Xavier Henriques, Maria João Catalão, Sara Pinheiro, Ana Rita Narciso, Francisco Mesquita, Bruno Manuel Saraiva, Madalena Carido, Didier Cabanes, Mariana Gomes Pinho, Sérgio Raposo Filipe

PLOS Pathogens: published June 22, 2022 | https://doi.org/10.1371/journal.ppat.1010516

DNA replication dynamics during erythrocytic schizogony in the malaria parasites Plasmodium falciparum and Plasmodium knowlesi

Jennifer McDonald, Catherine J. Merrick

PLOS Pathogens: published June 22, 2022 | https://doi.org/10.1371/journal.ppat.1010595

A single amino acid residue in bank vole prion protein drives permissiveness to Nor98/atypical scrapie and the emergence of multiple strain variants

Laura Pirisinu, Michele Angelo Di Bari, Claudia D’Agostino, Ilaria Vanni, Geraldina Riccardi, Stefano Marcon, Gabriele Vaccari, Barbara Chiappini, Sylvie L. Benestad, Umberto Agrimi, Romolo Nonno

PLOS Pathogens: published June 22, 2022 | https://doi.org/10.1371/journal.ppat.1010646

The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts

Priyanka Fernandes, Manon Loubens, Rémi Le Borgne, Carine Marinach, Béatrice Ardin, Sylvie Briquet, Laetitia Vincensini, Soumia Hamada, Bénédicte Hoareau-Coudert, Jean-Marc Verbavatz, Allon Weiner, Olivier Silvie

PLOS Pathogens: published June 22, 2022 | https://doi.org/10.1371/journal.ppat.1010643

Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis

Dinara Azimova, Nadia Herrera, Lucian Duvenage, Mark Voorhies, Rosa A. Rodriguez, Bevin C. English, Jennifer C. Hoving, Oren Rosenberg, Anita Sil

PLOS Pathogens: published June 22, 2022 | https://doi.org/10.1371/journal.ppat.1010417

Distinctive features of the respiratory syncytial virus priming loop compared to other non-segmented negative strand RNA viruses

Tessa N. Cressey, Afzaal M. Shareef, Victoria A. Kleiner, Sarah L. Noton, Patrick O. Byrne, Jason S. McLellan, Elke Mühlberger, Rachel Fearns

PLOS Pathogens: published June 22, 2022 | https://doi.org/10.1371/journal.ppat.1010451

A bivalent CMV vaccine formulated with human compatible TLR9 agonist CpG1018 elicits potent cellular and humoral immunity in HLA expressing mice

Vijayendra Dasari, Kirrilee Beckett, Shane Horsefield, George Ambalathingal, Rajiv Khanna

PLOS Pathogens: published June 23, 2022 | https://doi.org/10.1371/journal.ppat.1010403

Interactions between copper homeostasis and the fungal cell wall affect copper stress resistance

Corinna Probst, Sarela Garcia-Santamarina, Jacob T. Brooks, Inge Van Der Kloet, Oliver Baars, Martina Ralle, Dennis J. Thiele, J. Andrew Alspaugh

PLOS Pathogens: published June 23, 2022 | https://doi.org/10.1371/journal.ppat.1010195

HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5⁺ NK cells

Pia Fittje, Angelique Hœlzemer, Wilfredo F. Garcia-Beltran, Sarah Vollmers, Annika Niehrs, Kerri Hagemann, Glòria Martrus, Christian Körner, Frank Kirchhoff, Daniel Sauter, Marcus Altfeld

PLOS Pathogens: published June 24, 2022 | https://doi.org/10.1371/journal.ppat.1010572

Modeling recapitulates the heterogeneous outcomes of SARS-CoV-2 infection and quantifies the differences in the innate immune and CD8 T-cell responses between patients experiencing mild and severe symptoms

Budhaditya Chatterjee, Harshbir Singh Sandhu, Narendra M. Dixit

PLOS Pathogens: published June 27, 2022 | https://doi.org/10.1371/journal.ppat.1010630

Recombinant vesicular stomatitis vaccine against Nipah virus has a favorable safety profile: Model for assessment of live vaccines with neurotropic potential

Thomas P. Monath, Richard Nichols, Lynda Tussey, Kelly Scappaticci, Thaddeus G. Pullano, Mary D. Whiteman, Nikos Vasilakis, Shannan L. Rossi, Rafael Kroon Campos, Sasha R. Azar, Heidi M. Spratt, Brent L. Seaton, W. Tad Archambault, Yanina V. Costecalde, Evan H. Moore, Roger J. Hawks, Joan Fusco

PLOS Pathogens: published June 27, 2022 | https://doi.org/10.1371/journal.ppat.1010658

PHEV infection: A promising model of betacoronavirus-associated neurological and olfactory dysfunction

Junchao Shi, Zi Li, Jing Zhang, Rongyi Xu, Yungang Lan, Jiyu Guan, Rui Gao, Zhenzhen Wang, Huijun Lu, Baofeng Xu, Kui Zhao, Feng Gao, Wenqi He

PLOS Pathogens: published June 27, 2022 | https://doi.org/10.1371/journal.ppat.1010667

A Hepatitis C virus genotype 1b post-transplant isolate with high replication efficiency in cell culture and its adaptation to infectious virus production in vitro and in vivo

Christian Heuss, Paul Rothhaar, Rani Burm, Ji-Young Lee, Philipp Ralfs, Uta Haselmann, Luisa J. Ströh, Ombretta Colasanti, Cong Si Tran, Noemi Schäfer, Paul Schnitzler, Uta Merle, Ralf Bartenschlager, Arvind H. Patel, Frederik Graw, Thomas Krey, Vibor Laketa, Philip Meuleman, Volker Lohmann

PLOS Pathogens: published June 28, 2022 | https://doi.org/10.1371/journal.ppat.1010472

Helicobacter pylori pathogen inhibits cellular responses to oncogenic stress and apoptosis

Manikandan Palrasu, Elena Zaika, Kodisundaram Paulrasu, Ravindran Caspa Gokulan, Giovanni Suarez, Jianwen Que, Wael El-Rifai, Richard M. Peek Jr., Monica Garcia-Buitrago, Alexander I. Zaika

PLOS Pathogens: published June 29, 2022 | https://doi.org/10.1371/journal.ppat.1010628

A surface pocket in the cytoplasmic domain of the herpes simplex virus fusogen gB controls membrane fusion

Zemplen Pataki, Erin K. Sanders, Ekaterina E. Heldwein

PLOS Pathogens: published June 29, 2022 | https://doi.org/10.1371/journal.ppat.1010435

The centromeric histone CenH3 is recruited into the tombusvirus replication organelles

Paulina Alatriste Gonzalez, Peter D. Nagy

PLOS Pathogens: published June 29, 2022 | https://doi.org/10.1371/journal.ppat.1010653

The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

Allison J. Greaney, Rachel T. Eguia, Tyler N. Starr, Khadija Khan, Nicholas Franko, Jennifer K. Logue, Sandra M. Lord, Cate Speake, Helen Y. Chu, Alex Sigal, Jesse D. Bloom

PLOS Pathogens: published June 29, 2022 | https://doi.org/10.1371/journal.ppat.1010592

Genome-wide analysis of Brucella melitensis genes required throughout intranasal infection in mice

Georges Potemberg, Aurore Demars, Emeline Barbieux, Angéline Reboul, François-Xavier Stubbe, Malissia Galia, Maxime Lagneaux, Audrey Comein, Olivier Denis, David Pérez-Morga, Jean-Marie Vanderwinden, Xavier De Bolle, Eric Muraille

PLOS Pathogens: published June 30, 2022 | https://doi.org/10.1371/journal.ppat.1010621

Correction: STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus

Feng Gu, Chong Wang, Fang Wei, Yuyan Wang, Qing Zhu, Ling Ding, Wenjia Xu, Caixia Zhu, Cankun Cai, Zhikang Qian, Zhenghong Yuan, Erle Robertson, Qiliang Cai

PLOS Pathogens: published June 1, 2022 | https://doi.org/10.1371/journal.ppat.1010579

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Correction: Recombinant Lloviu virus as a tool to study viral replication and host responses

Adam J. Hume, Baylee Heiden, Judith Olejnik, Ellen L. Suder, Stephen Ross, Whitney A. Scoon, Esther Bullitt, Maria Ericsson, Mitchell R. White, Jacquelyn Turcinovic, Tran T. N. Thao, Ryan M. Hekman, Joseph E. Kaserman, Jessie Huang, Konstantinos-Dionysios Alysandratos, Gabor E. Toth, Ferenc Jakab, Darrell N. Kotton, Andrew A. Wilson, Andrew Emili, Volker Thiel, John H. Connor, Gabor Kemenesi, Daniel Cifuentes, Elke Mühlberger

PLOS Pathogens: published June 24, 2022 | https://doi.org/10.1371/journal.ppat.1010659

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