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Table of Contents

July 2021

Nipah virus is a highly pathogenic RNA virus, which, along with the closely related Hendra virus, has the potential to escalate into a pandemic. The figure shows the cryo-electron microscopy structure of a 13-subunit segment of the Nipah nucleocapsid protein assembly with RNA, with the RNA (purple neon) bound in a groove between an inner oligomerisation (pink) and outer exposed (green) domains. This helical ribonucleoprotein assembly serves to safeguard the viral genome by protecting it from degradation and host immune detection, and facilitating the packaging of the viral genome into new virion. Ker et al.

Image Credit: Nair S R, 2021

Pearls

Respiring to infect: Emerging links between mitochondria, the electron transport chain, and fungal pathogenesis

Braydon Black, Christopher Lee, Linda C. Horianopoulos, Won Hee Jung, James W. Kronstad

CRISPR-based antimicrobials to obstruct antibiotic-resistant and pathogenic bacteria

Dennise Palacios Araya, Kelli L. Palmer, Breck A. Duerkop

Helminth-mediated disease tolerance in TB: A role for microbiota?

Danielle Karo-Atar, Nargis Khan, Maziar Divangahi, Irah L. King

Host defense against fungal pathogens: Adaptable neutrophil responses and the promise of therapeutic opportunities?

Allison K. Scherer, Alex Hopke, David B. Sykes, Daniel Irimia, Michael K. Mansour

Aiming for a bull’s-eye: Targeting antifungals to fungi with dectin-decorated liposomes

Richard B. Meagher, Zachary A. Lewis, Suresh Ambati, Xiaorong Lin

Candida albicans colonization of the gastrointestinal tract: A double-edged sword

Rebeca Alonso-Monge, Mark S. Gresnigt, Elvira Román, Bernhard Hube, Jesús Pla

Cerebral organoids as a new model for prion disease

Bradley R. Groveman, Anna Smith, Katie Williams, Cathryn L. Haigh

From appressorium to transpressorium—Defining the morphogenetic basis of host cell invasion by the rice blast fungus

Neftaly Cruz-Mireles, Alice Bisola Eseola, Míriam Osés-Ruiz, Lauren S. Ryder, Nicholas J. Talbot

Reviews

Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration

Jürgen Krücken, Lindy Holden-Dye, Jennifer Keiser, Roger K. Prichard, Simon Townson, Benjamin L. Makepeace, Marc P. Hübner, Steffen R. Hahnel, Ivan Scandale, Achim Harder, Daniel Kulke

Antibody-independent functions of B cells during viral infections

Vinit Upasani, Izabela Rodenhuis-Zybert, Tineke Cantaert

Azole-resistant Aspergillus fumigatus in the environment: Identifying key reservoirs and hotspots of antifungal resistance

Caroline Burks, Alexandria Darby, Luisa Gómez Londoño, Michelle Momany, Marin T. Brewer

Research Articles

DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction

Pan Pan, Geng Li, Miaomiao Shen, Zhenyang Yu, Weiwei Ge, Zizhao Lao, Yaohua Fan, Keli Chen, Zhihao Ding, Wenbiao Wang, Pin Wan, Muhammad Adnan Shereen, Zhen Luo, Xulin Chen, Qiwei Zhang, Luping Lin, Jianguo Wu

Using Plasmodium knowlesi as a model for screening Plasmodium vivax blood-stage malaria vaccine targets reveals new candidates

Duncan N. Ndegwa, Prasun Kundu, Jessica B. Hostetler, Alejandro Marin-Menendez, Theo Sanderson, Kioko Mwikali, Lisa H. Verzier, Rachael Coyle, Sophie Adjalley, Julian C. Rayner

Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase

Yi Cai, Eleni Jaecklein, Jared S. Mackenzie, Kadamba Papavinasasundaram, Andrew J. Olive, Xinchun Chen, Adrie J. C. Steyn, Christopher M. Sassetti

Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy

Fredrik Barrenäs, Scott G. Hansen, Lynn Law, Connor Driscoll, Richard R. Green, Elise Smith, Jean Chang, Inah Golez, Taryn Urion, Xinxia Peng, Leanne Whitmore, Daniel Newhouse, Colette M. Hughes, David Morrow, Kurt T. Randall, Andrea N. Selseth, Julia C. Ford, Roxanne M. Gilbride, Bryan E. Randall, Emily Ainslie, Kelli Oswald, Rebecca Shoemaker, Randy Fast, William J. Bosche, Michael K. Axthelm, Yoshinori Fukazawa, George N. Pavlakis, Barbara K. Felber, Slim Fourati, Rafick-Pierre Sekaly, Jeffrey D. Lifson, Jan Komorowski, Ewelina Kosmider, Danica Shao, Wenjun Song, Paul T. Edlefsen, Louis J. Picker, Michael Gale Jr

Modifying TIMER to generate a slow-folding DsRed derivative for optimal use in quickly-dividing bacteria

Pavan Patel, Brendan J. O’Hara, Emily Aunins, Kimberly M. Davis

Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells

Sean Ganther, Allan Radaic, Erin Malone, Pachiyappan Kamarajan, Nai-Yuan Nicholas Chang, Christian Tafolla, Ling Zhan, J. Christopher Fenno, Yvonne L. Kapila

m6A RNA methylation facilitates pre-mRNA 3’-end formation and is essential for viability of Toxoplasma gondii

Michael J. Holmes, Leah R. Padgett, Matheus S. Bastos, William J. Sullivan Jr.

Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology

Nuno Brito Santos, Zoé Enderlin Vaz da Silva, Catarina Gomes, Celso A. Reis, Maria João Amorim

The multi-functional reovirus σ3 protein is a virulence factor that suppresses stress granule formation and is associated with myocardial injury

Yingying Guo, Meleana M. Hinchman, Mercedes Lewandrowski, Shaun T. Cross, Danica M. Sutherland, Olivia L. Welsh, Terence S. Dermody, John S. L. Parker

Intranasal gene therapy to prevent infection by SARS-CoV-2 variants

Joshua J. Sims, Jenny A. Greig, Kristofer T. Michalson, Sharon Lian, R. Alexander Martino, Rosemary Meggersee, Kevin B. Turner, Kalyani Nambiar, Cecilia Dyer, Christian Hinderer, Makoto Horiuchi, Hanying Yan, Xin Huang, Shu-Jen Chen, James M. Wilson

Genetic engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete

Emily Romeis, Lauren Tantalo, Nicole Lieberman, Quynh Phung, Alex Greninger, Lorenzo Giacani

Subacute SARS-CoV-2 replication can be controlled in the absence of CD8+ T cells in cynomolgus macaques

Takushi Nomura, Hiroyuki Yamamoto, Masako Nishizawa, Trang Thi Thu Hau, Shigeyoshi Harada, Hiroshi Ishii, Sayuri Seki, Midori Nakamura-Hoshi, Midori Okazaki, Sachie Daigen, Ai Kawana-Tachikawa, Noriyo Nagata, Naoko Iwata-Yoshikawa, Nozomi Shiwa, Shun Iida, Harutaka Katano, Tadaki Suzuki, Eun-Sil Park, Ken Maeda, Yuriko Suzaki, Yasushi Ami, Tetsuro Matano

A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site

Tatsuya Maehigashi, Seohyun Ahn, Uk-Il Kim, Jared Lindenberger, Adrian Oo, Pratibha C. Koneru, Bijan Mahboubi, Alan N. Engelman, Mamuka Kvaratskhelia, Kyungjin Kim, Baek Kim

Tropilaelaps mercedesae parasitism changes behavior and gene expression in honey bee workers

Jing Gao, Shilong Ma, Xinling Wang, Yang Yang, Qihua Luo, Xing Wang, Feng Liu, Qiang Wang, Zhongmin Fu, Qingyun Diao, Pingli Dai

Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaques

Koen K. A. Van Rompay, Katherine J. Olstad, Rebecca L. Sammak, Joseph Dutra, Jennifer K. Watanabe, Jodie L. Usachenko, Ramya Immareddy, Anil Verma, Yashavanth Shaan Lakshmanappa, Brian A. Schmidt, Jamin W. Roh, Sonny R. Elizaldi, A. Mark Allen, Frauke Muecksch, Julio C. C. Lorenzi, Sarah Lockwood, Rachel E. Pollard, JoAnn L. Yee, Peter B. Nham, Amir Ardeshir, Jesse D. Deere, Jean Patterson, Que Dang, Theodora Hatziioannou, Paul D. Bieniasz, Smita S. Iyer, Dennis J. Hartigan-O’Connor, Michel C. Nussenzweig, J. Rachel Reader

Varicella-zoster virus early infection but not complete replication is required for the induction of chronic hypersensitivity in rat models of postherpetic neuralgia

Benjamin E. Warner, Michael B. Yee, Mingdi Zhang, Rebecca S. Hornung, Benedikt B. Kaufer, Robert J. Visalli, Phillip R. Kramer, William F. Goins, Paul R. Kinchington

Listeria monocytogenes infection rewires host metabolism with regulatory input from type I interferons

Duygu Demiroz, Ekaterini Platanitis, Michael Bryant, Philipp Fischer, Michaela Prchal-Murphy, Alexander Lercher, Caroline Lassnig, Manuela Baccarini, Mathias Müller, Andreas Bergthaler, Veronika Sexl, Marlies Dolezal, Thomas Decker

SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues including the heart and kidney

Magen Ellen Francis, Una Goncin, Andrea Kroeker, Cynthia Swan, Robyn Ralph, Yao Lu, Athema Louise Etzioni, Darryl Falzarano, Volker Gerdts, Steven Machtaler, Jason Kindrachuk, Alyson Ann Kelvin

Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors

Chaitra Prabhakara, Rashmi Godbole, Parijat Sil, Sowmya Jahnavi, Shah-e-Jahan Gulzar, Thomas S. van Zanten, Dhruv Sheth, Neeraja Subhash, Anchal Chandra, Akshatha Shivaraj, Patricia Panikulam, Ibrahim U, Vijay Kumar Nuthakki, Theja Parassini Puthiyapurayil, Riyaz Ahmed, Ashaq Hussain Najar, Sai Manoz Lingamallu, Snigdhadev Das, Bhagyashri Mahajan, Praveen Vemula, Sandip B. Bharate, Parvinder Pal Singh, Ram Vishwakarma, Arjun Guha, Varadharajan Sundaramurthy, Satyajit Mayor

Transgenic expression of a T cell epitope in Strongyloides ratti reveals that helminth-specific CD4+ T cells constitute both Th2 and Treg populations

Bonnie Douglas, Yun Wei, Xinshe Li, Annabel Ferguson, Li-Yin Hung, Christopher Pastore, Jonathan R Kurtz, James B. McLachlan, Thomas J. Nolan, James Lok, De’Broski R. Herbert

Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF

Shivangi Rastogi, Sarah Ellinwood, Jacques Augenstreich, Katrin D. Mayer-Barber, Volker Briken

ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice

Jeffrey S. Bourgeois, Liuyang Wang, Agustin F. Rabino, Jeffrey Everitt, Monica I. Alvarez, Sahezeel Awadia, Erika S. Wittchen, Rafael Garcia-Mata, Dennis C. Ko

First historical genome of a crop bacterial pathogen from herbarium specimen: Insights into citrus canker emergence

Paola E. Campos, Clara Groot Crego, Karine Boyer, Myriam Gaudeul, Claudia Baider, Damien Richard, Olivier Pruvost, Philippe Roumagnac, Boris Szurek, Nathalie Becker, Lionel Gagnevin, Adrien Rieux

Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection

Nidhi Shukla, Sarah M. Roelle, Vinicius G. Suzart, Anna M. Bruchez, Kenneth A. Matreyek

In vitro adaptation and characterization of attenuated hypervariable region 1 swap chimeras of hepatitis C virus

Christina Holmboe Olesen, Elias H. Augestad, Fulvia Troise, Jens Bukh, Jannick Prentoe

Characterization of low-density granulocytes in COVID-19

Luz E. Cabrera, Pirkka T. Pekkarinen, Maria Alander, Kirsten H. A. Nowlan, Ngoc Anh Nguyen, Suvi Jokiranta, Suvi Kuivanen, Anu Patjas, Sointu Mero, Sari H. Pakkanen, Santtu Heinonen, Anu Kantele, Olli Vapalahti, Eliisa Kekäläinen, Tomas Strandin

ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions

Daniel J. Rawle, Thuy T. Le, Troy Dumenil, Kexin Yan, Bing Tang, Wilson Nguyen, Daniel Watterson, Naphak Modhiran, Jody Hobson-Peters, Cameron Bishop, Andreas Suhrbier

PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi

Ashley M. Groshong, André A. Grassmann, Amit Luthra, Melissa A. McLain, Anthony A. Provatas, Justin D. Radolf, Melissa J. Caimano

Definition of the immune evasion-replication interface of rabies virus P protein

Jingyu Zhan, Angela R. Harrison, Stephanie Portelli, Thanh Binh Nguyen, Isshu Kojima, Siqiong Zheng, Fei Yan, Tatsunori Masatani, Stephen M. Rawlinson, Ashish Sethi, Naoto Ito, David B. Ascher, Gregory W. Moseley, Paul R. Gooley

Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling

Marita Chakhtoura, Mike Fang, Rafael Cubas, Margaret H. O’Connor, Carmen N. Nichols, Brian Richardson, Aarthi Talla, Susan Moir, Mark J. Cameron, Virginie Tardif, Elias K. Haddad

pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production

Jiangnan Li, Jie Song, Li Kang, Li Huang, Shijun Zhou, Liang Hu, Jun Zheng, Changyao Li, Xianfeng Zhang, Xijun He, Dongming Zhao, Zhigao Bu, Changjiang Weng

Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition

Pieter C. Steketee, Emily A. Dickie, James Iremonger, Kathryn Crouch, Edith Paxton, Siddharth Jayaraman, Omar A. Alfituri, Georgina Awuah-Mensah, Ryan Ritchie, Achim Schnaufer, Tim Rowan, Harry P. de Koning, Catarina Gadelha, Bill Wickstead, Michael P. Barrett, Liam J. Morrison

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques

Jing Wen, Tracy Cheever, Lan Wang, Di Wu, Jason Reed, John Mascola, Xuejun Chen, Cuiping Liu, Amarendra Pegu, Jonah B. Sacha, Yunfeng Lu, Nancy L. Haigwood, Irvin S. Y. Chen

CryoEM structure of the Nipah virus nucleocapsid assembly

De-Sheng Ker, Huw T. Jenkins, Sandra J. Greive, Alfred A. Antson

Genome-wide analyses of human noroviruses provide insights on evolutionary dynamics and evidence of coexisting viral populations evolving under recombination constraints

Kentaro Tohma, Cara J. Lepore, Magaly Martinez, Juan I. Degiuseppe, Pattara Khamrin, Mayuko Saito, Holger Mayta, Amy U. Amanda Nwaba, Lauren A. Ford-Siltz, Kim Y. Green, Maria E. Galeano, Mirko Zimic, Juan A. Stupka, Robert H. Gilman, Niwat Maneekarn, Hiroshi Ushijima, Gabriel I. Parra

Evolution of the interactions between GII.4 noroviruses and histo-blood group antigens: Insights from experimental and computational studies

Yu Liang, Wei Bu Wang, Jing Zhang, Jun Wei Hou, Fang Tang, Xue Feng Zhang, Li Fang Du, Ji Guo Su, Qi Ming Li

Glycometabolism regulates hepatitis C virus release

Tao Yu, Qiankun Yang, Fangling Tian, Haishuang Chang, Zhenzheng Hu, Bowen Yu, Lin Han, Yifan Xing, Yaming Jiu, Yongning He, Jin Zhong

Adaptive selection of a prion strain conformer corresponding to established North American CWD during propagation of novel emergent Norwegian strains in mice expressing elk or deer prion protein

Jifeng Bian, Sehun Kim, Sarah J. Kane, Jenna Crowell, Julianna L. Sun, Jeffrey Christiansen, Eri Saijo, Julie A. Moreno, James DiLisio, Emily Burnett, Sandra Pritzkow, Damian Gorski, Claudio Soto, Terry J. Kreeger, Aru Balachandran, Gordon Mitchell, Michael W. Miller, Romolo Nonno, Turid Vikøren, Jørn Våge, Knut Madslien, Linh Tran, Tram Thu Vuong, Sylvie L. Benestad, Glenn C. Telling

Targeting human langerin promotes HIV-1 specific humoral immune responses

Jérôme Kervevan, Aurélie Bouteau, Juliane S. Lanza, Adele Hammoudi, Sandra Zurawski, Mathieu Surenaud, Lydie Dieudonné, Marion Bonnet, Cécile Lefebvre, Hakim Hocini, Romain Marlin, Aurélie Guguin, Barbara Hersant, Oana Hermeziu, Elisabeth Menu, Christine Lacabaratz, Jean-Daniel Lelièvre, Gerard Zurawski, Véronique Godot, Sandrine Henri, Botond Z. Igyártó, Yves Levy, Sylvain Cardinaud

Plasmodium falciparum PhIL1-associated complex plays an essential role in merozoite reorientation and invasion of host erythrocytes

Ekta Saini, Pradeep Kumar Sheokand, Vaibhav Sharma, Prakhar Agrawal, Inderjeet Kaur, Shailja Singh, Asif Mohmmed, Pawan Malhotra

Viromics unveils extraordinary genetic diversity of the family Closteroviridae in wild citrus

Qiyan Liu, Song Zhang, Shiqiang Mei, Yan Zhou, Jianhua Wang, Guan-Zhu Han, Lei Chen, Changyong Zhou, Mengji Cao

Pore-forming alpha-hemolysin efficiently improves the immunogenicity and protective efficacy of protein antigens

Jin-Tao Zou, Hai-Ming Jing, Yue Yuan, Lang-Huan Lei, Zhi-Fu Chen, Qiang Gou, Qing-Shan Xiong, Xiao-Li Zhang, Zhuo Zhao, Xiao-Kai Zhang, Hao Zeng, Quan-Ming Zou, Jin-Yong Zhang

COVID-19 virtual patient cohort suggests immune mechanisms driving disease outcomes

Adrianne L. Jenner, Rosemary A. Aogo, Sofia Alfonso, Vivienne Crowe, Xiaoyan Deng, Amanda P. Smith, Penelope A. Morel, Courtney L. Davis, Amber M. Smith, Morgan Craig

Antiviral RISC mainly targets viral mRNA but not genomic RNA of tospovirus

Hao Hong, Chunli Wang, Ying Huang, Min Xu, Jiaoling Yan, Mingfeng Feng, Jia Li, Yajie Shi, Min Zhu, Danyu Shen, Peijun Wu, Richard Kormelink, Xiaorong Tao

Altered microRNA expression in COVID-19 patients enables identification of SARS-CoV-2 infection

Ryan J. Farr, Christina L. Rootes, Louise C. Rowntree, Thi H. O. Nguyen, Luca Hensen, Lukasz Kedzierski, Allen C. Cheng, Katherine Kedzierska, Gough G. Au, Glenn A. Marsh, Seshadri S. Vasan, Chwan Hong Foo, Christopher Cowled, Cameron R. Stewart

SARS-CoV-2-specific circulating T follicular helper cells correlate with neutralizing antibodies and increase during early convalescence

Sushma Boppana, Kai Qin, Jacob K. Files, Ronnie M. Russell, Regina Stoltz, Frederic Bibollet-Ruche, Anju Bansal, Nathan Erdmann, Beatrice H. Hahn, Paul A. Goepfert

A key antisense sRNA modulates the oxidative stress response and virulence in Xanthomonas oryzae pv. oryzicola

Yan Wu, Sai Wang, Wenhan Nie, Peihong Wang, Luoyi Fu, Iftikhar Ahmad, Bo Zhu, Gongyou Chen

CBS-derived H2S facilitates host colonization of Vibrio cholerae by promoting the iron-dependent catalase activity of KatB

Yao Ma, Xiaoman Yang, Hongou Wang, Zixin Qin, Chunrong Yi, Changping Shi, Mei Luo, Guozhong Chen, Jin Yan, Xiaoyun Liu, Zhi Liu

Inhibition of polo-like kinase 1 (PLK1) facilitates reactivation of gamma-herpesviruses and their elimination

Ayan Biswas, Dawei Zhou, Guillaume N. Fiches, Zhenyu Wu, Xuefeng Liu, Qin Ma, Weiqiang Zhao, Jian Zhu, Netty G. Santoso

Efficient interspecies transmission of synthetic prions

Alyssa J. Block, Ronald A. Shikiya, Thomas E. Eckland, Anthony E. Kincaid, Ryan W. Walters, Jiyan Ma, Jason C. Bartz

Early antibody responses associated with survival in COVID19 patients

Zhao-Hua Zhou, Sai Dharmarajan, Mari Lehtimaki, Susan L. Kirshner, Steven Kozlowski

Acyl-CoA oxidase ACOX-1 interacts with a peroxin PEX-5 to play roles in larval development of Haemonchus contortus

Hengzhi Shi, Xiaocui Huang, Xueqiu Chen, Yi Yang, Zhao Wang, Yimin Yang, Fei Wu, Jingru Zhou, Chaoqun Yao, Guangxu Ma, Aifang Du

Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages

Ruth Forman, Larisa Logunova, Hannah Smith, Kelly Wemyss, Iris Mair, Louis Boon, Judith E. Allen, Werner Muller, Joanne L. Pennock, Kathryn J. Else

Virulence and community dynamics of fungal species with vertical and horizontal transmission on a plant with multiple infections

Kai Fang, Jie Zhou, Lin Chen, Yu-Xuan Li, Ai-Ling Yang, Xing-Fan Dong, Han-Bo Zhang

CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD

Ondrej Cerny, Camilla Godlee, Romina Tocci, Nancy E. Cross, Haoran Shi, James C. Williamson, Eric Alix, Paul J. Lehner, David W. Holden

Aryl hydrocarbon receptor activation by Lactobacillus reuteri tryptophan metabolism alleviates Escherichia coli-induced mastitis in mice

Caijun Zhao, Xiaoyu Hu, Lijuan Bao, Keyi Wu, Lianjun Feng, Min Qiu, Haoyang Hao, Yunhe Fu, Naisheng Zhang

Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1-skewed proinflammatory immune responses

James Fisher, Galen Card, Yuejin Liang, Brandon Trent, Holly Rosenzweig, Lynn Soong

Neuroinvasiveness of the MR766 strain of Zika virus in IFNAR-/- mice maps to prM residues conserved amongst African genotype viruses

Eri Nakayama, Fumihiro Kato, Shigeru Tajima, Shinya Ogawa, Kexin Yan, Kenta Takahashi, Yuko Sato, Tadaki Suzuki, Yasuhiro Kawai, Takuya Inagaki, Satoshi Taniguchi, Thuy T. Le, Bing Tang, Natalie A. Prow, Akihiko Uda, Takahiro Maeki, Chang-Kweng Lim, Alexander A. Khromykh, Andreas Suhrbier, Masayuki Saijo

Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection

Melanie Brügger, Thomas Démoulins, G. Tuba Barut, Beatrice Zumkehr, Blandina I. Oliveira Esteves, Kemal Mehinagic, Quentin Haas, Aline Schögler, Marie-Anne Rameix-Welti, Jean-François Eléouët, Ueli Moehrlen, Thomas M. Marti, Ralph A. Schmid, Artur Summerfield, Horst Posthaus, Nicolas Ruggli, Sean R. R. Hall, Marco P. Alves

New and distinct chronic wasting disease strains associated with cervid polymorphism at codon 116 of the Prnp gene

Samia Hannaoui, Elizabeth Triscott, Camilo Duque Velásquez, Sheng Chun Chang, Maria Immaculata Arifin, Irina Zemlyankina, Xinli Tang, Trent Bollinger, Holger Wille, Debbie McKenzie, Sabine Gilch

A novel heteromeric pantothenate kinase complex in apicomplexan parasites

Erick T. Tjhin, Vanessa M. Howieson, Christina Spry, Giel G. van Dooren, Kevin J. Saliba

Host tropism determination by convergent evolution of immunological evasion in the Lyme disease system

Thomas M. Hart, Alan P. Dupuis II, Danielle M. Tufts, Anna M. Blom, Simon R. Starkey, Ryan O. M. Rego, Sanjay Ram, Peter Kraiczy, Laura D. Kramer, Maria A. Diuk-Wasser, Sergios-Orestis Kolokotronis, Yi-Pin Lin