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April 2020

Yersinia pestis induces, resists and then consolidates the formation of a bactericidal matrix in the flea’s proventriculus, which hastens its transmission to the mammalian host. In this fluorescence image, myriad of GFP+ Y. pestis are entrapped in a mass fulfilling the anterior spineless region and the spined region (that autofluoresces in yellow) of the proventriculus. Here, the mass also extends in the esophagus. Dewitte et al

Image Credit: Sebbane F

Pearls

Japanese encephalitis virus and its mechanisms of neuroinvasion

Justin T. Hsieh, Ashley L. St. John

Fine-tuning a blunt tool: Regulation of viral host shutoff RNases

Raecliffe Daly, Denys A. Khaperskyy, Marta Maria Gaglia

The clue is in the lipid A: Rapid detection of colistin resistance

R. Christopher D. Furniss, Markus Kostrzewa, Despoina A. I. Mavridou, Gerald Larrouy-Maumus

The entanglement between flaviviruses and ER-shaping proteins

Maaran Michael Rajah, Blandine Monel, Olivier Schwartz

Bats reveal the true power of influenza A virus adaptability

Kevin Ciminski, Florian Pfaff, Martin Beer, Martin Schwemmle

Drosophila as a model for the gut microbiome

William B. Ludington, William W. Ja

Mycobacterium simiae: Harmless colonizer or deadly pathogen?

Jean-Francois Jabbour, Amal Hamieh, Sima L. Sharara, Souha S. Kanj

Review

Competent but complex communication: The phenomena of pheromone-responsive plasmids

Amy J. Sterling, William J. Snelling, Patrick J. Naughton, Nigel G. Ternan, James S. G. Dooley

Research Articles

Discovery and characterization of a Gram-positive Pel polysaccharide biosynthetic gene cluster

Gregory B. Whitfield, Lindsey S. Marmont, Cedoljub Bundalovic-Torma, Erum Razvi, Elyse J. Roach, Cezar M. Khursigara, John Parkinson, P. Lynne Howell

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Chemical intervention of influenza virus mRNA nuclear export

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EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor

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ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response

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