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April 2019

"Fig3. The Fusarium graminearum FGRRES_16221 receptor and specific receptor sub-domains are important to virulence on wheat. Complementation of the receptor null mutants with the native FGRES_16221 gene restores full virulence. This non-classical receptor physically interacts with intracellular G-proteins. The absence of the receptor dysregulates virulence traits, which amounts to an enhanced wheat defensive response that restricts the progression of infection." Dilks et al.

Image Credit: Dilks T and Brown NA (2019)

Review

The possible role of cross-reactive dengue virus antibodies in Zika virus pathogenesis

Thomas Langerak, Noreen Mumtaz, Vera I. Tolk, Eric C. M. van Gorp, Byron E. Martina, Barry Rockx, Marion P. G. Koopmans

Research Articles

Non-canonical fungal G-protein coupled receptors promote Fusarium head blight on wheat

Tess Dilks, Kirstie Halsey, Rebecca P. De Vos, Kim E. Hammond-Kosack, Neil Andrew Brown

Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes

Sean P. O’Brien, Adrienne E. Swanstrom, Amarendra Pegu, Sung-Youl Ko, Taina T. Immonen, Gregory Q. Del Prete, Christine M. Fennessey, Jason Gorman, Kathryn E. Foulds, Stephen D. Schmidt, Nicole Doria-Rose, Carolyn Williamson, Theodora Hatziioannou, Paul D. Bieniasz, Hui Li, George M. Shaw, John R. Mascola, Richard A. Koup, Peter D. Kwong, Jeffrey D. Lifson, Mario Roederer, Brandon F. Keele

USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA

Liya Ye, Qiang Zhang, Tianzi Liuyu, Zhigao Xu, Meng-Xin Zhang, Min-Hua Luo, Wen-Bo Zeng, Qiyun Zhu, Dandan Lin, Bo Zhong

Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites

Mary S. Dickinson, Lindsey N. Anderson, Bobbie-Jo M. Webb-Robertson, Joshua R. Hansen, Richard D. Smith, Aaron T. Wright, Kevin Hybiske

A unique dynamin-related protein is essential for mitochondrial fission in Toxoplasma gondii

Carmen Melatti, Manuela Pieperhoff, Leandro Lemgruber, Ehmke Pohl, Lilach Sheiner, Markus Meissner

Viral RNA-dependent RNA polymerase mutants display an altered mutation spectrum resulting in attenuation in both mosquito and vertebrate hosts

K. Lane Warmbrod, Edward I. Patterson, Tiffany F. Kautz, Adam Stanton, Dedeke Rockx-Brouwer, Birte K. Kalveram, Kamil Khanipov, Saravanan Thangamani, Yuriy Fofanov, Naomi L. Forrester

Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection

Sam X. Li, Sharon Sen, Jennifer M. Schneider, Ka-Na Xiong, Nichole M. Nusbacher, Nancy Moreno-Huizar, Michael Shaffer, Abigail J. S. Armstrong, Erin Severs, Kristine Kuhn, Charles P. Neff, Martin McCarter, Thomas Campbell, Catherine A. Lozupone, Brent E. Palmer

Subversion of natural killer cell responses by a cytomegalovirus-encoded soluble CD48 decoy receptor

Pablo Martínez-Vicente, Domènec Farré, Carolina Sánchez, Antonio Alcamí, Pablo Engel, Ana Angulo

Supramolecular arrangement of the full-length Zika virus NS5

Diego S. Ferrero, Victor M. Ruiz-Arroyo, Nicolas Soler, Isabel Usón, Alba Guarné, Núria Verdaguer

Unique features in the intracellular transport of typhoid toxin revealed by a genome-wide screen

Shu-Jung Chang, Sheng Chih Jin, Xuyao Jiao, Jorge E. Galán

Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection

Taishi Kimura, Claudia T. Flynn, Mehrdad Alirezaei, Ganes C. Sen, J. Lindsay Whitton

Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice

Vuong B. Lê, Julia Dubois, Christian Couture, Marie-Hélène Cavanagh, Olus Uyar, Andres Pizzorno, Manuel Rosa-Calatrava, Marie-Ève Hamelin, Guy Boivin

A model of chronic, transmissible Otitis Media in mice

Kalyan K. Dewan, Dawn L. Taylor-Mulneix, Laura L. Campos, Amanda L. Skarlupka, Shannon M. Wagner, Valerie E. Ryman, Monica C. Gestal, Longhua Ma, Uriel Blas-Machado, Brian T. Faddis, Eric T. Harvill

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Corrections

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