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November 2016

A skeletal muscle myotube infected by a Trichinella spiralis parasitic nematode is visualized in a cross-section of rat muscle tissue. The section has been probed with anti-TsUbE2L3 (red), a parasite-derived ubiquitin E2 conjugating enzyme that is secreted by the worm into the host cell during infection. This image shows TsUbE2L3 localizing to the stacks of stichocyte cells within the worm's secretory organ. Nuclei have been counterstained with DAPI (blue). White et al.

Image Credit: Rhiannon R. White, Department of Life Sciences, Imperial College, London, UK

Reviews

The Strange Lifestyle of Multipartite Viruses

Anne Sicard, Yannis Michalakis, Serafín Gutiérrez, Stéphane Blanc

Microsporidia: Why Make Nucleotides if You Can Steal Them?

Paul Dean, Robert P. Hirt, T. Martin Embley

Research Articles

Acute Malaria Induces PD1+CTLA4+ Effector T Cells with Cell-Extrinsic Suppressor Function

Maria Sophia Mackroth, Annemieke Abel, Christiane Steeg, Julian Schulze zur Wiesch, Thomas Jacobs

Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole

Aurélie Fougère, Andrew P. Jackson, Dafni Paraskevi Bechtsi, Joanna A. M. Braks, Takeshi Annoura, Jannik Fonager, Roberta Spaccapelo, Jai Ramesar, Séverine Chevalley-Maurel, Onny Klop, Annelies M. A. van der Laan, Hans J. Tanke, Clemens H. M. Kocken, Erica M. Pasini, Shahid M. Khan, Ulrike Böhme, Christiaan van Ooij, Thomas D. Otto, Chris J. Janse, Blandine Franke-Fayard

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