July 2016

False-colored SEM image (43.5 x 37.6 microns) showing Trypanosoma brucei parasites (blue) in intricate interaction with an adipocyte (grey) in the ear dermis of a mouse bitten by an infected tsetse fly. The dermis represents the site where tsetse flies inoculate African trypanosomes and from which the host is systemically colonized to cause sleeping sickness. In the dermis, a transient parasite subpopulation remains that is interacting with adipocytes. Caljon et al.

Image Credit: Guy Caljon - Institute of Tropical Medicine Antwerp and University of Antwerp; Marjorie Vermeersch and David Pérez-Morga - Université Libre de Bruxelles.

Pearls

Escaping Host Immunity: New Tricks for Plant Pathogens

Ren Na, Mark Gijzen

PLOS Pathogens: published July 7, 2016 | https://doi.org/10.1371/journal.ppat.1005631

Commensal–Pathogen Interactions along the Human Nasal Passages

Silvio D. Brugger, Lindsey Bomar, Katherine P. Lemon

PLOS Pathogens: published July 7, 2016 | https://doi.org/10.1371/journal.ppat.1005633

A Sweet Response to a Sour Situation: The Role of Soluble Pattern Recognition Receptors in the Innate Immune Response to Invasive Aspergillus fumigatus Infections

Stefan Bidula, Silke Schelenz

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005637

Sporothrix Species Causing Outbreaks in Animals and Humans Driven by Animal–Animal Transmission

Anderson Messias Rodrigues, G. Sybren de Hoog, Zoilo Pires de Camargo

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005638

Untangling the Diverse and Redundant Mechanisms of Staphylococcus aureus Biofilm Formation

Marta Zapotoczna, Eoghan O’Neill, James P. O'Gara

PLOS Pathogens: published July 21, 2016 | https://doi.org/10.1371/journal.ppat.1005671

The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease

Kelly J. Pittman, Luke C. Glover, Liuyang Wang, Dennis C. Ko

PLOS Pathogens: published July 21, 2016 | https://doi.org/10.1371/journal.ppat.1005680

Conquering Neutrophils

Simon Döhrmann, Jason N. Cole, Victor Nizet

PLOS Pathogens: published July 28, 2016 | https://doi.org/10.1371/journal.ppat.1005682

Major Sensing Proteins in Pathogenic Fungi: The Hybrid Histidine Kinase Family

Anaïs Hérivaux, Yee-Seul So, Amandine Gastebois, Jean-Paul Latgé, Jean-Philippe Bouchara, Yong-Sun Bahn, Nicolas Papon

PLOS Pathogens: published July 28, 2016 | https://doi.org/10.1371/journal.ppat.1005683

Research Matters

Getting Back to the Basics of Translational Research

Paul M. Lieberman

PLOS Pathogens: published July 21, 2016 | https://doi.org/10.1371/journal.ppat.1005534

From Slow Viruses to Prions

Jason C. Bartz

PLOS Pathogens: published July 7, 2016 | https://doi.org/10.1371/journal.ppat.1005543

Research Articles

Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection

Matthias Hoffmann, Nikos Pantazis, Genevieve E. Martin, Stephen Hickling, Jacob Hurst, Jodi Meyerowitz, Christian B. Willberg, Nicola Robinson, Helen Brown, Martin Fisher, Sabine Kinloch, Abdel Babiker, Jonathan Weber, Nneka Nwokolo, Julie Fox, Sarah Fidler, Rodney Phillips, John Frater, SPARTAC and CHERUB Investigators

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005661

Biosynthesis of Antibiotic Leucinostatins in Bio-control Fungus Purpureocillium lilacinum and Their Inhibition on Phytophthora Revealed by Genome Mining

Gang Wang, Zhiguo Liu, Runmao Lin, Erfeng Li, Zhenchuan Mao, Jian Ling, Yuhong Yang, Wen-Bing Yin, Bingyan Xie

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005685

The Actin Filament-Binding Protein Coronin Regulates Motility in Plasmodium Sporozoites

Kartik S. Bane, Simone Lepper, Jessica Kehrer, Julia M. Sattler, Mirko Singer, Miriam Reinig, Dennis Klug, Kirsten Heiss, Jake Baum, Ann-Kristin Mueller, Friedrich Frischknecht

PLOS Pathogens: published July 13, 2016 | https://doi.org/10.1371/journal.ppat.1005710

Hepatitis C Virus Core Protein Promotes miR-122 Destabilization by Inhibiting GLD-2

Geon-Woo Kim, Seung-Hoon Lee, Hee Cho, Minwoo Kim, Eui-Cheol Shin, Jong-Won Oh

PLOS Pathogens: published July 1, 2016 | https://doi.org/10.1371/journal.ppat.1005714

Metarhizium brunneum Blastospore Pathogenesis in Aedes aegypti Larvae: Attack on Several Fronts Accelerates Mortality

Abeer M. Alkhaibari, Aline T. Carolino, Sare I. Yavasoglu, Thierry Maffeis, Thalles C. Mattoso, James C. Bull, Richard I. Samuels, Tariq M. Butt

PLOS Pathogens: published July 7, 2016 | https://doi.org/10.1371/journal.ppat.1005715

Cryo-electron Microscopy Structure of the Native Prototype Foamy Virus Glycoprotein and Virus Architecture

Grégory Effantin, Leandro F. Estrozi, Nick Aschman, Patricia Renesto, Nicole Stanke, Dirk Lindemann, Guy Schoehn, Winfried Weissenhorn

PLOS Pathogens: published July 11, 2016 | https://doi.org/10.1371/journal.ppat.1005721

Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite’s Chloroquine Resistance Transporter

Sashika N. Richards, Megan N. Nash, Eileen S. Baker, Michael W. Webster, Adele M. Lehane, Sarah H. Shafik, Rowena E. Martin

PLOS Pathogens: published July 21, 2016 | https://doi.org/10.1371/journal.ppat.1005725

Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-α Resistance

David F. Boyd, Amit Sharma, Daryl Humes, Cecilia Cheng-Mayer, Julie Overbaugh

PLOS Pathogens: published July 11, 2016 | https://doi.org/10.1371/journal.ppat.1005727

Preventing Vaccine-Derived Poliovirus Emergence during the Polio Endgame

Margarita Pons-Salort, Cara C. Burns, Hil Lyons, Isobel M. Blake, Hamid Jafari, M. Steven Oberste, Olen M. Kew, Nicholas C. Grassly

PLOS Pathogens: published July 6, 2016 | https://doi.org/10.1371/journal.ppat.1005728

Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse

Karthickeyan Chella Krishnan, Santhosh Mukundan, Jeyashree Alagarsamy, Junguk Hur, Suba Nookala, Nikolai Siemens, Mattias Svensson, Ole Hyldegaard, Anna Norrby-Teglund, Malak Kotb

PLOS Pathogens: published July 11, 2016 | https://doi.org/10.1371/journal.ppat.1005732

Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells

Deborah Frenkel, Fengqiu Zhang, Patrick Guirnalda, Carole Haynes, Viki Bockstal, Magdalena Radwanska, Stefan Magez, Samuel J. Black

PLOS Pathogens: published July 12, 2016 | https://doi.org/10.1371/journal.ppat.1005733

A Putative Small Solute Transporter Is Responsible for the Secretion of G377 and TRAP-Containing Secretory Vesicles during Plasmodium Gamete Egress and Sporozoite Motility

Jessica Kehrer, Mirko Singer, Leandro Lemgruber, Patricia A. G. C. Silva, Friedrich Frischknecht, Gunnar R. Mair

PLOS Pathogens: published July 18, 2016 | https://doi.org/10.1371/journal.ppat.1005734

Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner

Stephanie Pfaender, Elena Grabski, Claudia N. Detje, Nina Riebesehl, Stefan Lienenklaus, Eike Steinmann, Ulrich Kalinke, Thomas Pietschmann

PLOS Pathogens: published July 6, 2016 | https://doi.org/10.1371/journal.ppat.1005736

Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability

Henry Puerta-Guardo, Dustin R. Glasner, Eva Harris

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005738

PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis

Philana Ling Lin, Pauline Maiello, Hannah P. Gideon, M. Teresa Coleman, Anthony M. Cadena, Mark A. Rodgers, Robert Gregg, Melanie O’Malley, Jaime Tomko, Daniel Fillmore, L. James Frye, Tara Rutledge, Robert M. DiFazio, Christopher Janssen, Edwin Klein, Peter L. Andersen, Sarah M. Fortune, JoAnne L. Flynn

PLOS Pathogens: published July 5, 2016 | https://doi.org/10.1371/journal.ppat.1005739

An In Vivo Selection Identifies Listeria monocytogenes Genes Required to Sense the Intracellular Environment and Activate Virulence Factor Expression

Michelle L. Reniere, Aaron T. Whiteley, Daniel A. Portnoy

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005741

Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

Cecilia Rademeyer, Bette Korber, Michael S. Seaman, Elena E. Giorgi, Ruwayhida Thebus, Alexander Robles, Daniel J. Sheward, Kshitij Wagh, Jetta Garrity, Brittany R. Carey, Hongmei Gao, Kelli M. Greene, Haili Tang, Gama P. Bandawe, Jinny C. Marais, Thabo E. Diphoko, Peter Hraber, Nancy Tumba, Penny L. Moore, Glenda E. Gray, James Kublin, M. Juliana McElrath, Marion Vermeulen, Keren Middelkoop, Linda-Gail Bekker, Michael Hoelscher, Leonard Maboko, Joseph Makhema, Merlin L. Robb, Salim Abdool Karim, Quarraisha Abdool Karim, Jerome H. Kim, Beatrice H. Hahn, Feng Gao, Ronald Swanstrom, Lynn Morris, David C. Montefiori, Carolyn Williamson

PLOS Pathogens: published July 19, 2016 | https://doi.org/10.1371/journal.ppat.1005742

Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice

Sisi He, Xuefeng Li, Rongpeng Li, Lizhu Fang, Lingyun Sun, Yongsheng Wang, Min Wu

PLOS Pathogens: published July 7, 2016 | https://doi.org/10.1371/journal.ppat.1005743

The Dermis as a Delivery Site of Trypanosoma brucei for Tsetse Flies

Guy Caljon, Nick Van Reet, Carl De Trez, Marjorie Vermeersch, David Pérez-Morga, Jan Van Den Abbeele

PLOS Pathogens: published July 21, 2016 | https://doi.org/10.1371/journal.ppat.1005744

Transdifferentiation and Proliferation in Two Distinct Hemocyte Lineages in Drosophila melanogaster Larvae after Wasp Infection

Ines Anderl, Laura Vesala, Teemu O. Ihalainen, Leena-Maija Vanha-aho, István Andó, Mika Rämet, Dan Hultmark

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005746

Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle

Vignesh Kumar Gunasekharan, Yan Li, Jorge Andrade, Laimonis A. Laimins

PLOS Pathogens: published July 7, 2016 | https://doi.org/10.1371/journal.ppat.1005747

Human Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like Response

Thomas Harwardt, Simone Lukas, Marion Zenger, Tobias Reitberger, Daniela Danzer, Theresa Übner, Diane C. Munday, Michael Nevels, Christina Paulus

PLOS Pathogens: published July 7, 2016 | https://doi.org/10.1371/journal.ppat.1005748

CD103⁺ Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans

Nancy Van Prooyen, C. Allen Henderson, Davina Hocking Murray, Anita Sil

PLOS Pathogens: published July 26, 2016 | https://doi.org/10.1371/journal.ppat.1005749

Rabies Internalizes into Primary Peripheral Neurons via Clathrin Coated Pits and Requires Fusion at the Cell Body

Silvia Piccinotti, Sean P. J. Whelan

PLOS Pathogens: published July 27, 2016 | https://doi.org/10.1371/journal.ppat.1005753

RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection

Matheswaran Kandasamy, Amol Suryawanshi, Smanla Tundup, Jasmine T. Perez, Mirco Schmolke, Santhakumar Manicassamy, Balaji Manicassamy

PLOS Pathogens: published July 20, 2016 | https://doi.org/10.1371/journal.ppat.1005754

A Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig Cytomegalovirus

Stewart Coleman, K. Yeon Choi, Matthew Root, Alistair McGregor

PLOS Pathogens: published July 7, 2016 | https://doi.org/10.1371/journal.ppat.1005755

Static Clathrin Assemblies at the Peripheral Vacuole—Plasma Membrane Interface of the Parasitic Protozoan Giardia lamblia

Jon Paulin Zumthor, Lenka Cernikova, Samuel Rout, Andres Kaech, Carmen Faso, Adrian B. Hehl

PLOS Pathogens: published July 20, 2016 | https://doi.org/10.1371/journal.ppat.1005756

CdtR Regulates TcdA and TcdB Production in Clostridium difficile

Shelley A. Lyon, Melanie L. Hutton, Julian I. Rood, Jackie K. Cheung, Dena Lyras

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005758

Vectors as Epidemiological Sentinels: Patterns of Within-Tick Borrelia burgdorferi Diversity

Katharine S. Walter, Giovanna Carpi, Benjamin R. Evans, Adalgisa Caccone, Maria A. Diuk-Wasser

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005759

A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans

Cecilia S. Lindestam Arlehamn, Denise M. McKinney, Chelsea Carpenter, Sinu Paul, Virginie Rozot, Edward Makgotlho, Yolande Gregg, Michele van Rooyen, Joel D. Ernst, Mark Hatherill, Willem A. Hanekom, Bjoern Peters, Thomas J. Scriba, Alessandro Sette

PLOS Pathogens: published July 13, 2016 | https://doi.org/10.1371/journal.ppat.1005760

CD4⁺ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART

Rémi Fromentin, Wendy Bakeman, Mariam B. Lawani, Gabriela Khoury, Wendy Hartogensis, Sandrina DaFonseca, Marisela Killian, Lorrie Epling, Rebecca Hoh, Elizabeth Sinclair, Frederick M. Hecht, Peter Bacchetti, Steven G. Deeks, Sharon R. Lewin, Rafick-Pierre Sékaly, Nicolas Chomont

PLOS Pathogens: published July 14, 2016 | https://doi.org/10.1371/journal.ppat.1005761

Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae

Jing Li, Jing-Wen Li, Zhixing Feng, Juanjuan Wang, Haoran An, Yanni Liu, Yang Wang, Kailing Wang, Xuegong Zhang, Zhun Miao, Wenbo Liang, Robert Sebra, Guilin Wang, Wen-Ching Wang, Jing-Ren Zhang

PLOS Pathogens: published July 18, 2016 | https://doi.org/10.1371/journal.ppat.1005762

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Wesley C. Van Voorhis, John H. Adams, Roberto Adelfio, Vida Ahyong, Myles H. Akabas, Pietro Alano, Aintzane Alday, Yesmalie Alemán Resto, Aishah Alsibaee, Ainhoa Alzualde, Katherine T. Andrews, Simon V. Avery, Vicky M. Avery, Lawrence Ayong, Mark Baker, Stephen Baker, Choukri Ben Mamoun, Sangeeta Bhatia, Quentin Bickle, Lotfi Bounaadja, Tana Bowling, Jürgen Bosch, Lauren E. Boucher, Fabrice F. Boyom, Jose Brea, Marian Brennan, Audrey Burton, Conor R. Caffrey, Grazia Camarda, Manuela Carrasquilla, Dee Carter, Maria Belen Cassera, Ken Chih-Chien Cheng, Worathad Chindaudomsate, Anthony Chubb, Beatrice L. Colon, Daisy D. Colón-López, Yolanda Corbett, Gregory J. Crowther, Noemi Cowan, Sarah D’Alessandro, Na Le Dang, Michael Delves, Joseph L. DeRisi, Alan Y. Du, Sandra Duffy, Shimaa Abd El-Salam El-Sayed, Michael T. Ferdig, José A. Fernández Robledo, David A. Fidock, Isabelle Florent, Patrick V. T. Fokou, Ani Galstian, Francisco Javier Gamo, Suzanne Gokool, Ben Gold, Todd Golub, Gregory M. Goldgof, Rajarshi Guha, W. Armand Guiguemde, Nil Gural, R. Kiplin Guy, Michael A. E. Hansen, Kirsten K. Hanson, Andrew Hemphill, Rob Hooft van Huijsduijnen, Takaaki Horii, Paul Horrocks, Tyler B. Hughes, Christopher Huston, Ikuo Igarashi, Katrin Ingram-Sieber, Maurice A. Itoe, Ajit Jadhav, Amornrat Naranuntarat Jensen, Laran T. Jensen, Rays H. Y. Jiang, Annette Kaiser, Jennifer Keiser, Thomas Ketas, Sebastien Kicka, Sunyoung Kim, Kiaran Kirk, Vidya P. Kumar, Dennis E. Kyle, Maria Jose Lafuente, Scott Landfear, Nathan Lee, Sukjun Lee, Adele M. Lehane, Fengwu Li, David Little, Liqiong Liu, Manuel Llinás, Maria I. Loza, Aristea Lubar, Leonardo Lucantoni, Isabelle Lucet, Louis Maes, Dalu Mancama, Nuha R. Mansour, Sandra March, Sheena McGowan, Iset Medina Vera, Stephan Meister, Luke Mercer, Jordi Mestres, Alvine N. Mfopa, Raj N. Misra, Seunghyun Moon, John P. Moore, Francielly Morais Rodrigues da Costa, Joachim Müller, Arantza Muriana, Stephen Nakazawa Hewitt, Bakela Nare, Carl Nathan, Nathalie Narraidoo, Sujeevi Nawaratna, Kayode K. Ojo, Diana Ortiz, Gordana Panic, George Papadatos, Silvia Parapini, Kailash Patra, Ngoc Pham, Sarah Prats, David M. Plouffe, Sally-Ann Poulsen, Anupam Pradhan, Celia Quevedo, Ronald J. Quinn, Christopher A. Rice, Mohamed Abdo Rizk, Andrea Ruecker, Robert St. Onge, Rafaela Salgado Ferreira, Jasmeet Samra, Natalie G. Robinett, Ulrich Schlecht, Marjorie Schmitt, Filipe Silva Villela, Francesco Silvestrini, Robert Sinden, Dennis A. Smith, Thierry Soldati, Andreas Spitzmüller, Serge Maximilian Stamm, David J. Sullivan, William Sullivan, Sundari Suresh, Brian M. Suzuki, Yo Suzuki, S. Joshua Swamidass, Donatella Taramelli, Lauve R. Y. Tchokouaha, Anjo Theron, David Thomas, Kathryn F. Tonissen, Simon Townson, Abhai K. Tripathi, Valentin Trofimov, Kenneth O. Udenze, Imran Ullah, Cindy Vallieres, Edgar Vigil, Joseph M. Vinetz, Phat Voong Vinh, Hoan Vu, Nao-aki Watanabe, Kate Weatherby, Pamela M. White, Andrew F. Wilks, Elizabeth A. Winzeler, Edward Wojcik, Melanie Wree, Wesley Wu, Naoaki Yokoyama, Paul H. A. Zollo, Nada Abla, Benjamin Blasco, Jeremy Burrows, Benoît Laleu, Didier Leroy, Thomas Spangenberg, Timothy Wells, Paul A. Willis

PLOS Pathogens: published July 28, 2016 | https://doi.org/10.1371/journal.ppat.1005763

Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus

Ying Ren, Peng Zhao, Jin Liu, Yukang Yuan, Qiao Cheng, Yibo Zuo, Liping Qian, Chang Liu, Tingting Guo, Liting Zhang, Xiaofang Wang, Guanghui Qian, Lemin Li, Jun Ge, Jianfeng Dai, Sidong Xiong, Hui Zheng

PLOS Pathogens: published July 19, 2016 | https://doi.org/10.1371/journal.ppat.1005764

Multiple Domain Associations within the Arabidopsis Immune Receptor RPP1 Regulate the Activation of Programmed Cell Death

Karl J. Schreiber, Adam Bentham, Simon J. Williams, Bostjan Kobe, Brian J. Staskawicz

PLOS Pathogens: published July 18, 2016 | https://doi.org/10.1371/journal.ppat.1005769

CD4⁺ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection

Fadel Sayes, Alexandre Pawlik, Wafa Frigui, Matthias I. Gröschel, Samuel Crommelynck, Catherine Fayolle, Felipe Cia, Gregory J. Bancroft, Daria Bottai, Claude Leclerc, Roland Brosch, Laleh Majlessi

PLOS Pathogens: published July 28, 2016 | https://doi.org/10.1371/journal.ppat.1005770

Spliceosome SNRNP200 Promotes Viral RNA Sensing and IRF3 Activation of Antiviral Response

Nicolas Tremblay, Martin Baril, Laurent Chatel-Chaix, Salwa Es-Saad, Alex Young Park, Robert K. Koenekoop, Daniel Lamarre

PLOS Pathogens: published July 25, 2016 | https://doi.org/10.1371/journal.ppat.1005772

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

Fabio Gsaller, Peter Hortschansky, Takanori Furukawa, Paul D. Carr, Bharat Rash, Javier Capilla, Christoph Müller, Franz Bracher, Paul Bowyer, Hubertus Haas, Axel A. Brakhage, Michael J. Bromley

PLOS Pathogens: published July 20, 2016 | https://doi.org/10.1371/journal.ppat.1005775

Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection

Roshell Muir, Talibah Metcalf, Virginie Tardif, Hiroshi Takata, Nittaya Phanuphak, Eugene Kroon, Donn J. Colby, Rapee Trichavaroj, Victor Valcour, Merlin L. Robb, Nelson L. Michael, Jintanat Ananworanich, Lydie Trautmann, Elias K. Haddad, RV254/SEARCH010 RV304/SEARCH 013 Study Groups

PLOS Pathogens: published July 27, 2016 | https://doi.org/10.1371/journal.ppat.1005777

The 17D-204 Vaccine Strain-Induced Protection against Virulent Yellow Fever Virus Is Mediated by Humoral Immunity and CD4+ but not CD8+ T Cells

Alan M. Watson, L. K. Metthew Lam, William B. Klimstra, Kate D. Ryman

PLOS Pathogens: published July 27, 2016 | https://doi.org/10.1371/journal.ppat.1005786

Hyphopodium-Specific VdNoxB/VdPls1-Dependent ROS-Ca²⁺ Signaling Is Required for Plant Infection by Verticillium dahliae

Yun-Long Zhao, Ting-Ting Zhou, Hui-Shan Guo

PLOS Pathogens: published July 27, 2016 | https://doi.org/10.1371/journal.ppat.1005793

KSHV-Mediated Regulation of Par3 and SNAIL Contributes to B-Cell Proliferation

Hem C. Jha, Zhiguo Sun, Santosh K. Upadhyay, Darine W. El-Naccache, Rajnish K. Singh, Sushil K. Sahu, Erle S. Robertson

PLOS Pathogens: published July 27, 2016 | https://doi.org/10.1371/journal.ppat.1005801

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