January 2014

Scanning Electron Micrograph showing Macropinocytic uptake of Mycobacteria in Activated Macrophages. See Pieters et al.

Image Credit: Somdeb BoseDasgupta and Jean Pieters in collaboration with the Center for Microscopy, University of Basel

Opinion

Lyme Disease: Call for a “Manhattan Project” to Combat the Epidemic

Raphael B. Stricker, Lorraine Johnson

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003796

Pearls

Human and Plant Fungal Pathogens: The Role of Secondary Metabolites

Daniel H. Scharf, Thorsten Heinekamp, Axel A. Brakhage

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003859

HIV-1 Accessory Proteins Adapt Cellular Adaptors to Facilitate Immune Evasion

David R. Collins, Kathleen L. Collins

PLOS Pathogens: published January 23, 2014 | https://doi.org/10.1371/journal.ppat.1003851

Ranaviruses: Not Just for Frogs

V. Gregory Chinchar, Thomas B. Waltzek

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003850

Synthesis and Biological Properties of Fungal Glucosylceramide

Maurizio Del Poeta, Leonardo Nimrichter, Marcio L. Rodrigues, Chiara Luberto

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003832

Effectors and Effector Delivery in Magnaporthe oryzae

Shijie Zhang, Jin-Rong Xu

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003826

Review

From Scourge to Cure: Tumour-Selective Viral Pathogenesis as a New Strategy against Cancer

Carolina S. Ilkow, Stephanie L. Swift, John C. Bell, Jean-Simon Diallo

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003836

Research Articles

Loss of Circulating CD4 T Cells with B Cell Helper Function during Chronic HIV Infection

Kristin L. Boswell, Robert Paris, Eli Boritz, David Ambrozak, Takuya Yamamoto, Sam Darko, Kaska Wloka, Adam Wheatley, Sandeep Narpala, Adrian McDermott, Mario Roederer, Richard Haubrich, Mark Connors, Julie Ake, Daniel C. Douek, Jerome Kim, Constantinos Petrovas, Richard A. Koup

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003853

Investigation of Acetylcholine Receptor Diversity in a Nematode Parasite Leads to Characterization of Tribendimidine- and Derquantel-Sensitive nAChRs

Samuel K. Buxton, Claude L. Charvet, Cedric Neveu, Jacques Cabaret, Jacques Cortet, Nicolas Peineau, Melanie Abongwa, Elise Courtot, Alan P. Robertson, Richard J. Martin

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003870

Inflammatory Stimuli Reprogram Macrophage Phagocytosis to Macropinocytosis for the Rapid Elimination of Pathogens

Somdeb BoseDasgupta, Jean Pieters

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003879

Decreases in Colonic and Systemic Inflammation in Chronic HIV Infection after IL-7 Administration

Irini Sereti, Jacob D. Estes, William L. Thompson, David R. Morcock, Margaret A. Fischl, Thérèse Croughs, Stéphanie Beq, Sylvie Lafaye de Micheaux, Michael D. Yao, Alexander Ober, Eleanor M. P. Wilson, Ven Natarajan, Hiromi Imamichi, Mohamed R. Boulassel, Michael M. Lederman, Jean-Pierre Routy

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003890

RNA-seq Analysis of Host and Viral Gene Expression Highlights Interaction between Varicella Zoster Virus and Keratinocyte Differentiation

Meleri Jones, Inga R. Dry, Dan Frampton, Manuraj Singh, Ravinder K. Kanda, Michael B. Yee, Paul Kellam, Michael Hollinshead, Paul R. Kinchington, Edel A. O'Toole, Judith Breuer

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003896

Electron Tomography of HIV-1 Infection in Gut-Associated Lymphoid Tissue

Mark S. Ladinsky, Collin Kieffer, Gregory Olson, Maud Deruaz, Vladimir Vrbanac, Andrew M. Tager, Douglas S. Kwon, Pamela J. Bjorkman

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003899

Leishmania-Mediated Inhibition of Iron Export Promotes Parasite Replication in Macrophages

Rym Ben-Othman, Andrew R. Flannery, Danilo C. Miguel, Diane M. Ward, Jerry Kaplan, Norma W. Andrews

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003901

Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection

Ashima Bhaskar, Manbeena Chawla, Mansi Mehta, Pankti Parikh, Pallavi Chandra, Devayani Bhave, Dhiraj Kumar, Kate S. Carroll, Amit Singh

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003902

Plasmacytoid Dendritic Cell Dynamics Tune Interferon-Alfa Production in SIV-Infected Cynomolgus Macaques

Timothée Bruel, Stéphanie Dupuy, Thomas Démoulins, Christine Rogez-Kreuz, Jacques Dutrieux, Aurélien Corneau, Antonio Cosma, Rémi Cheynier, Nathalie Dereuddre-Bosquet, Roger Le Grand, Bruno Vaslin

PLOS Pathogens: published January 30, 2014 | https://doi.org/10.1371/journal.ppat.1003915

Variation in RNA Virus Mutation Rates across Host Cells

Marine Combe, Rafael Sanjuán

PLOS Pathogens: published January 23, 2014 | https://doi.org/10.1371/journal.ppat.1003855

Intranasal Vaccination Promotes Detrimental Th17-Mediated Immunity against Influenza Infection

Asher Maroof, Yvonne M. Yorgensen, Yufeng Li, Jay T. Evans

PLOS Pathogens: published January 23, 2014 | https://doi.org/10.1371/journal.ppat.1003875

Absence of Intestinal PPARγ Aggravates Acute Infectious Colitis in Mice through a Lipocalin-2–Dependent Pathway

Parag Kundu, Teo Wei Ling, Agata Korecka, Yinghui Li, Rossana D'Arienzo, Ralph M. Bunte, Thorsten Berger, Velmurugesan Arulampalam, Pierre Chambon, Tak Wah Mak, Walter Wahli, Sven Pettersson

PLOS Pathogens: published January 23, 2014 | https://doi.org/10.1371/journal.ppat.1003887

Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism

Eleanor C. Saunders, William W. Ng, Joachim Kloehn, Jennifer M. Chambers, Milica Ng, Malcolm J. McConville

PLOS Pathogens: published January 23, 2014 | https://doi.org/10.1371/journal.ppat.1003888

Detection of Host-Derived Sphingosine by Pseudomonas aeruginosa Is Important for Survival in the Murine Lung

Annette E. LaBauve, Matthew J. Wargo

PLOS Pathogens: published January 23, 2014 | https://doi.org/10.1371/journal.ppat.1003889

Preservation of Tetherin and CD4 Counter-Activities in Circulating Vpu Alleles despite Extensive Sequence Variation within HIV-1 Infected Individuals

Suzanne Pickering, Stephane Hué, Eun-Young Kim, Susheel Reddy, Steven M. Wolinsky, Stuart J. D. Neil

PLOS Pathogens: published January 23, 2014 | https://doi.org/10.1371/journal.ppat.1003895

Origin, Migration Routes and Worldwide Population Genetic Structure of the Wheat Yellow Rust Pathogen Puccinia striiformis f.sp. tritici

Sajid Ali, Pierre Gladieux, Marc Leconte, Angélique Gautier, Annemarie F. Justesen, Mogens S. Hovmøller, Jérôme Enjalbert, Claude de Vallavieille-Pope

PLOS Pathogens: published January 23, 2014 | https://doi.org/10.1371/journal.ppat.1003903

KSHV 2.0: A Comprehensive Annotation of the Kaposi's Sarcoma-Associated Herpesvirus Genome Using Next-Generation Sequencing Reveals Novel Genomic and Functional Features

Carolina Arias, Ben Weisburd, Noam Stern-Ginossar, Alexandre Mercier, Alexis S. Madrid, Priya Bellare, Meghan Holdorf, Jonathan S. Weissman, Don Ganem

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003847

Single Cell Stochastic Regulation of Pilus Phase Variation by an Attenuation-like Mechanism

Camille Danne, Sarah Dubrac, Patrick Trieu-Cuot, Shaynoor Dramsi

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003860

Nutrient Limitation Governs Staphylococcus aureus Metabolism and Niche Adaptation in the Human Nose

Bernhard Krismer, Manuel Liebeke, Daniela Janek, Mulugeta Nega, Maren Rautenberg, Gabriele Hornig, Clemens Unger, Christopher Weidenmaier, Michael Lalk, Andreas Peschel

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003862

Kaposi's Sarcoma Associated Herpesvirus Tegument Protein ORF75 Is Essential for Viral Lytic Replication and Plays a Critical Role in the Antagonization of ND10-Instituted Intrinsic Immunity

Florian Full, Doris Jungnickl, Nina Reuter, Elke Bogner, Kevin Brulois, Brigitte Scholz, Michael Stürzl, Jinjong Myoung, Jae U. Jung, Thomas Stamminger, Armin Ensser

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003863

HIV Protective KIR3DL1/S1-HLA-B Genotypes Influence NK Cell-Mediated Inhibition of HIV Replication in Autologous CD4 Targets

Rujun Song, Irene Lisovsky, Bertrand Lebouché, Jean-Pierre Routy, Julie Bruneau, Nicole F. Bernard

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003867

Phosphoenolpyruvate Carboxylase Identified as a Key Enzyme in Erythrocytic Plasmodium falciparum Carbon Metabolism

Janet Storm, Sonal Sethia, Gavin J. Blackburn, Achuthanunni Chokkathukalam, David G. Watson, Rainer Breitling, Graham H. Coombs, Sylke Müller

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003876

Alphavirus Mutator Variants Present Host-Specific Defects and Attenuation in Mammalian and Insect Models

Kathryn Rozen-Gagnon, Kenneth A. Stapleford, Vanesa Mongelli, Hervé Blanc, Anna-Bella Failloux, Maria-Carla Saleh, Marco Vignuzzi

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003877

Serotonin Signaling in Schistosoma mansoni: A Serotonin–Activated G Protein-Coupled Receptor Controls Parasite Movement

Nicholas Patocka, Nidhi Sharma, Mohammed Rashid, Paula Ribeiro

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003878

A Substrate-Fusion Protein Is Trapped inside the Type III Secretion System Channel in Shigella flexneri

Kim Dohlich, Anna Brotcke Zumsteg, Christian Goosmann, Michael Kolbe

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003881

Gammaherpesviral Gene Expression and Virion Composition Are Broadly Controlled by Accelerated mRNA Degradation

Emma Abernathy, Karen Clyde, Rukhsana Yeasmin, Laurie T. Krug, Al Burlingame, Laurent Coscoy, Britt Glaunsinger

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003882

The Arabidopsis miR472-RDR6 Silencing Pathway Modulates PAMP- and Effector-Triggered Immunity through the Post-transcriptional Control of Disease Resistance Genes

Martine Boccara, Alexis Sarazin, Odon Thiébeauld, Florence Jay, Olivier Voinnet, Lionel Navarro, Vincent Colot

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003883

Lu/BCAM Adhesion Glycoprotein Is a Receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1)

Marianne Piteau, Panagiotis Papatheodorou, Carsten Schwan, Andreas Schlosser, Klaus Aktories, Gudula Schmidt

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003884

Malaria-Induced NLRP12/NLRP3-Dependent Caspase-1 Activation Mediates Inflammation and Hypersensitivity to Bacterial Superinfection

Marco A. Ataide, Warrison A. Andrade, Dario S. Zamboni, Donghai Wang, Maria do Carmo Souza, Bernardo S. Franklin, Samir Elian, Flaviano S. Martins, Dhelio Pereira, George Reed, Katherine A. Fitzgerald, Douglas T. Golenbock, Ricardo T. Gazzinelli

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003885

Regulators of Trypanosoma brucei Cell Cycle Progression and Differentiation Identified Using a Kinome-Wide RNAi Screen

Nathaniel G. Jones, Elizabeth B. Thomas, Elaine Brown, Nicholas J. Dickens, Tansy C. Hammarton, Jeremy C. Mottram

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003886

Glutamate Utilization Couples Oxidative Stress Defense and the Tricarboxylic Acid Cycle in Francisella Phagosomal Escape

Elodie Ramond, Gael Gesbert, Mélanie Rigard, Julien Dairou, Marion Dupuis, Iharilalao Dubail, Karin Meibom, Thomas Henry, Monique Barel, Alain Charbit

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003893

TREM-1 Deficiency Can Attenuate Disease Severity without Affecting Pathogen Clearance

Benjamin Weber, Steffen Schuster, Daniel Zysset, Silvia Rihs, Nina Dickgreber, Christian Schürch, Carsten Riether, Mark Siegrist, Christoph Schneider, Helga Pawelski, Ursina Gurzeler, Pascal Ziltener, Vera Genitsch, Fabienne Tacchini-Cottier, Adrian Ochsenbein, Willy Hofstetter, Manfred Kopf, Thomas Kaufmann, Annette Oxenius, Walter Reith, Leslie Saurer, Christoph Mueller

PLOS Pathogens: published January 16, 2014 | https://doi.org/10.1371/journal.ppat.1003900

Narrow Bottlenecks Affect Pea Seedborne Mosaic Virus Populations during Vertical Seed Transmission but not during Leaf Colonization

Frédéric Fabre, Benoît Moury, Elisabeth Ida Johansen, Vincent Simon, Mireille Jacquemond, Rachid Senoussi

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003833

Cell Tropism Predicts Long-term Nucleotide Substitution Rates of Mammalian RNA Viruses

Allison L. Hicks, Siobain Duffy

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003838

IFNγ/IL-10 Co-producing Cells Dominate the CD4 Response to Malaria in Highly Exposed Children

Prasanna Jagannathan, Ijeoma Eccles-James, Katherine Bowen, Felistas Nankya, Ann Auma, Samuel Wamala, Charles Ebusu, Mary K. Muhindo, Emmanuel Arinaitwe, Jessica Briggs, Bryan Greenhouse, Jordan W. Tappero, Moses R. Kamya, Grant Dorsey, Margaret E. Feeney

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003864

In Vivo Functions of CPSF6 for HIV-1 as Revealed by HIV-1 Capsid Evolution in HLA-B27-Positive Subjects

Matthew S. Henning, Brittany N. Dubose, Mallori J. Burse, Christopher Aiken, Masahiro Yamashita

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003868

Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC

Joseph D. Batchelor, Brian M. Malpede, Natalie S. Omattage, Gregory T. DeKoster, Katherine A. Henzler-Wildman, Niraj H. Tolia

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003869

Targeted Cytotoxic Therapy Kills Persisting HIV Infected Cells During ART

Paul W. Denton, Julie M. Long, Stephen W. Wietgrefe, Craig Sykes, Rae Ann Spagnuolo, Olivia D. Snyder, Katherine Perkey, Nancie M. Archin, Shailesh K. Choudhary, Kuo Yang, Michael G. Hudgens, Ira Pastan, Ashley T. Haase, Angela D. Kashuba, Edward A. Berger, David M. Margolis, J. Victor Garcia

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003872

NsrR, GadE, and GadX Interplay in Repressing Expression of the Escherichia coli O157:H7 LEE Pathogenicity Island in Response to Nitric Oxide

Priscilla Branchu, Stéphanie Matrat, Marjolaine Vareille, Annie Garrivier, Alexandra Durand, Sébastien Crépin, Josée Harel, Grégory Jubelin, Alain P. Gobert

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003874

CTCF and Rad21 Act as Host Cell Restriction Factors for Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Lytic Replication by Modulating Viral Gene Transcription

Da-Jiang Li, Dinesh Verma, Tim Mosbruger, Sankar Swaminathan

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003880

Parvovirus-Induced Depletion of Cyclin B1 Prevents Mitotic Entry of Infected Cells

Richard O. Adeyemi, David J. Pintel

PLOS Pathogens: published January 9, 2014 | https://doi.org/10.1371/journal.ppat.1003891

iNKT Cell Production of GM-CSF Controls Mycobacterium tuberculosis

Alissa C. Rothchild, Pushpa Jayaraman, Cláudio Nunes-Alves, Samuel M. Behar

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003805

Variable Suites of Non-effector Genes Are Co-regulated in the Type III Secretion Virulence Regulon across the Pseudomonas syringae Phylogeny

Tatiana S. Mucyn, Scott Yourstone, Abigail L. Lind, Surojit Biswas, Marc T. Nishimura, David A. Baltrus, Jason S. Cumbie, Jeff H. Chang, Corbin D. Jones, Jeffery L. Dangl, Sarah R. Grant

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003807

Host-Specific Enzyme-Substrate Interactions in SPM-1 Metallo-β-Lactamase Are Modulated by Second Sphere Residues

Lisandro J. González, Diego M. Moreno, Robert A. Bonomo, Alejandro J. Vila

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003817

Characterisation of a Multi-ligand Binding Chemoreceptor CcmL (Tlp3) of Campylobacter jejuni

Hossinur Rahman, Rebecca M. King, Lucy K. Shewell, Evgeny A. Semchenko, Lauren E. Hartley-Tassell, Jennifer C. Wilson, Christopher J. Day, Victoria Korolik

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003822

Lysine Acetyltransferase GCN5b Interacts with AP2 Factors and Is Required for Toxoplasma gondii Proliferation

Jiachen Wang, Stacy E. Dixon, Li-Min Ting, Ting-Kai Liu, Victoria Jeffers, Matthew M. Croken, Myrasol Calloway, Dominique Cannella, Mohamed Ali Hakimi, Kami Kim, William J. Sullivan Jr

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003830

A Single Amino Acid in the Stalk Region of the H1N1pdm Influenza Virus HA Protein Affects Viral Fusion, Stability and Infectivity

Christopher R. Cotter, Hong Jin, Zhongying Chen

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003831

Recovery of an Antiviral Antibody Response following Attrition Caused by Unrelated Infection

Dorothy H. L. Ng, John J. Skehel, George Kassiotis, Jean Langhorne

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003843

Inflammation Fuels Colicin Ib-Dependent Competition of Salmonella Serovar Typhimurium and E. coli in Enterobacterial Blooms

Lubov Petkova Nedialkova, Rémy Denzler, Martin B. Koeppel, Manuel Diehl, Diana Ring, Thorsten Wille, Roman G. Gerlach, Bärbel Stecher

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003844

Suppression of Interferon Lambda Signaling by SOCS-1 Results in Their Excessive Production during Influenza Virus Infection

Haitao Wei, Song Wang, Qinghuang Chen, Yuhai Chen, Xiaojuan Chi, Lianfeng Zhang, Shile Huang, George F. Gao, Ji-Long Chen

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003845

Group B Streptococcus Engages an Inhibitory Siglec through Sialic Acid Mimicry to Blunt Innate Immune and Inflammatory Responses In Vivo

Yung-Chi Chang, Joshua Olson, Federico C. Beasley, Christine Tung, Jiquan Zhang, Paul R. Crocker, Ajit Varki, Victor Nizet

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003846

DAMP Molecule S100A9 Acts as a Molecular Pattern to Enhance Inflammation during Influenza A Virus Infection: Role of DDX21-TRIF-TLR4-MyD88 Pathway

Su-Yu Tsai, Jesus A. Segovia, Te-Hung Chang, Ian R. Morris, Michael T. Berton, Philippe A. Tessier, Mélanie R. Tardif, Annabelle Cesaro, Santanu Bose

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003848

Recruitment of PfSET2 by RNA Polymerase II to Variant Antigen Encoding Loci Contributes to Antigenic Variation in P. falciparum

Uchechi E. Ukaegbu, Sandeep P. Kishore, Dacia L. Kwiatkowski, Chethan Pandarinath, Noa Dahan-Pasternak, Ron Dzikowski, Kirk W. Deitsch

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003854

Enhancing Virus-Specific Immunity In Vivo by Combining Therapeutic Vaccination and PD-L1 Blockade in Chronic Hepadnaviral Infection

Jia Liu, Ejuan Zhang, Zhiyong Ma, Weimin Wu, Anna Kosinska, Xiaoyong Zhang, Inga Möller, Pia Seiz, Dieter Glebe, Baoju Wang, Dongliang Yang, Mengji Lu, Michael Roggendorf

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003856

Murine Gammaherpesvirus M2 Protein Induction of IRF4 via the NFAT Pathway Leads to IL-10 Expression in B Cells

Udaya S. Rangaswamy, Samuel H. Speck

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003858

STING-Dependent Type I IFN Production Inhibits Cell-Mediated Immunity to Listeria monocytogenes

Kristina A. Archer, Juliana Durack, Daniel A. Portnoy

PLOS Pathogens: published January 2, 2014 | https://doi.org/10.1371/journal.ppat.1003861

Cover

Inflammatory Stimuli Reprogram Macrophage Phagocytosis to Macropinocytosis for the Rapid Elimination of Pathogens

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