The mouse host cell restricted attenuated vaccinia virus MVA is able to replicate and produce mature virions (green dots) in murine embryo fibroblasts (MEFs) lacking the cellular dual phosphatase DUSP1, involved in MAPK signaling pathway. See Cáceres et al.
Image Credit: Ana Cáceres, Beatriz Perdiguero, Carmen E. Gómez, Maria Victoria Cepeda, Carme Caelles, Carlos Oscar Sorzano, and Mariano Esteban (Centro Nacional de Biotecnología, CSIC and University of Barcelona, Spain).
Pearls
Colonization Resistance: Battle of the Bugs or Ménage à Trois with the Host?
PLOS Pathogens: published November 21, 2013 | https://doi.org/10.1371/journal.ppat.1003730
Disease to Dirt: The Biology of Microbial Amyloids
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Fungal Immune Evasion in a Model Host–Pathogen Interaction: Candida albicans Versus Macrophages
PLOS Pathogens: published November 21, 2013 | https://doi.org/10.1371/journal.ppat.1003741
The Biology and Taxonomy of Head and Body Lice—Implications for Louse-Borne Disease Prevention
PLOS Pathogens: published November 14, 2013 | https://doi.org/10.1371/journal.ppat.1003724
Microbial Endocrinology in the Microbiome-Gut-Brain Axis: How Bacterial Production and Utilization of Neurochemicals Influence Behavior
PLOS Pathogens: published November 14, 2013 | https://doi.org/10.1371/journal.ppat.1003726
Baculoviruses: Sophisticated Pathogens of Insects
PLOS Pathogens: published November 14, 2013 | https://doi.org/10.1371/journal.ppat.1003729
The Regulation of Trypanosome Gene Expression by RNA-Binding Proteins
PLOS Pathogens: published November 7, 2013 | https://doi.org/10.1371/journal.ppat.1003680
How Do Viruses Avoid Inhibition by Endogenous Cellular MicroRNAs?
PLOS Pathogens: published November 7, 2013 | https://doi.org/10.1371/journal.ppat.1003694
DNA Damage Repair and Bacterial Pathogens
PLOS Pathogens: published November 7, 2013 | https://doi.org/10.1371/journal.ppat.1003711
Research Articles
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PLOS Pathogens: published November 21, 2013 | https://doi.org/10.1371/journal.ppat.1003750
The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
PLOS Pathogens: published November 21, 2013 | https://doi.org/10.1371/journal.ppat.1003754
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