December 2006

This negative-stained transmission electron micrograph (TEM) depicts the ultrastructural details of a number of influenza virus particles, or "virions." A member of the taxonomic family Orthomyxoviridae, the influenza virus is a single-stranded RNA organism (see Nelson et al).

Image Credit: F. A. Murphy, Centers for Disease Control and Prevention

Review

Fungal Invasion of Normally Non-Phagocytic Host Cells

Scott G Filler, Donald C Sheppard

PLOS Pathogens: published December 29, 2006 | https://doi.org/10.1371/journal.ppat.0020129

Research Articles

Cross-Talk with Myeloid Accessory Cells Regulates Human Natural Killer Cell Interferon-γ Responses to Malaria

Kirsty C Newman, Daniel S Korbel, Julius C Hafalla, Eleanor M Riley

PLOS Pathogens: published December 8, 2006 | https://doi.org/10.1371/journal.ppat.0020118

Stochastic Processes Are Key Determinants of Short-Term Evolution in Influenza A Virus

Martha I Nelson, Lone Simonsen, Cecile Viboud, Mark A Miller, Jill Taylor, Kirsten St George, Sara B Griesemer, Elodie Ghedin, Naomi A Sengamalay, David J Spiro, Igor Volkov, Bryan T Grenfell, David J Lipman, Jeffery K Taubenberger, Edward C Holmes

PLOS Pathogens: published December 1, 2006 | https://doi.org/10.1371/journal.ppat.0020125

HIV-1 Vpr-Induced Apoptosis Is Cell Cycle Dependent and Requires Bax but Not ANT

Joshua L Andersen, Jason L DeHart, Erik S Zimmerman, Orly Ardon, Baek Kim, Guillaume Jacquot, Serge Benichou, Vicente Planelles

PLOS Pathogens: published December 1, 2006 | https://doi.org/10.1371/journal.ppat.0020127

Endogenous MMTV Proviruses Induce Susceptibility to Both Viral and Bacterial Pathogens

Sanchita Bhadra, Mary M Lozano, Shelley M Payne, Jaquelin P Dudley

PLOS Pathogens: published December 1, 2006 | https://doi.org/10.1371/journal.ppat.0020128

NFAT5 Regulates HIV-1 in Primary Monocytes via a Highly Conserved Long Terminal Repeat Site

Shahin Ranjbar, Alla V Tsytsykova, Sang-Kyung Lee, Ricardo Rajsbaum, James V Falvo, Judy Lieberman, Premlata Shankar, Anne E Goldfeld

PLOS Pathogens: published December 15, 2006 | https://doi.org/10.1371/journal.ppat.0020130

Dynamics of the Cellular Metabolome during Human Cytomegalovirus Infection

Joshua Munger, Sunil U Bajad, Hilary A Coller, Thomas Shenk, Joshua D Rabinowitz

PLOS Pathogens: published December 15, 2006 | https://doi.org/10.1371/journal.ppat.0020132

Fz2 and Cdc42 Mediate Melanization and Actin Polymerization but Are Dispensable for Plasmodium Killing in the Mosquito Midgut

Shin-Hong Shiao, Miranda M. A Whitten, Daniel Zachary, Jules A Hoffmann, Elena A Levashina

PLOS Pathogens: published December 29, 2006 | https://doi.org/10.1371/journal.ppat.0020133

The Fittest versus the Flattest: Experimental Confirmation of the Quasispecies Effect with Subviral Pathogens

Francisco M Codoñer, José-Antonio Darós, Ricard V Solé, Santiago F Elena

PLOS Pathogens: published December 29, 2006 | https://doi.org/10.1371/journal.ppat.0020136

Correction

Correction: Stochastic Processes Are Key Determinants of Short-Term Evolution in Influenza A Virus

Martha I Nelson, Lone Simonsen, Cecile Viboud, Mark A Miller, Jill Taylor, Kirsten St. George, Sara B Griesemer, Elodie Ghedin, Naomi A Sengamalay, David J Spiro, Igor Volkov, Brian T Grenfell, David J Lipman, Jeffrey K Taubenberger, Edward C Holmes

PLOS Pathogens: published December 29, 2006 | https://doi.org/10.1371/journal.ppat.0020138

Cover

Influenza virus particles