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Correction: HTLV-1 bZIP Factor Enhances T-cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors

  • Haruka Kinosada,
  • Jun-ichirou Yasunaga,
  • Kazuya Shimura,
  • Paola Miyazato,
  • Chiho Onishi,
  • Tomonori Iyoda,
  • Kayo Inaba,
  • Masao Matsuoka
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Fig 5 is incorrect. Fig 5B was generated using a statistical software, GraphPad PRISM. The data points in Fig 5B were duplicated by human error, and in addition, the Jurkat-mock with stimulation (+) and without stimulation (-) data were switched. These errors do not influence the results and conclusion of this study. The authors have provided a corrected Fig 5 here.

Fig 5. HBZ inhibits co-localization of PD-1 and SHP-2.

(A) Staining of unstimulated or pervanadate-stimulated Jurkat-mock and Jurkat-HBZ cells was performed using antibodies against PD-1 (green) and SHP-2 (red). All scale bars are 5 μm. Three representative images derived from each sample are shown. Relative fluorescence intensities of PD-1 (green line) and SHP-2 (red line) were obtained on the white dotted line. (B) Co-localization of PD-1 and SHP-2 was judged by Pearson’s correlation coefficient between green and red channels. Each circle represents an individual cell. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test.


  1. 1. Kinosada H, Yasunaga J-i, Shimura K, Miyazato P, Onishi C, Iyoda T, et al. (2017) HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors. PLoS Pathog 13(1): e1006120. pmid:28046066