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PLoS Pathogens Issue Image | Vol. 16(2) February 2020

PLoS Pathogens Issue Image | Vol. 16(2) February 2020

PLOS
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Colonization of a three-dimensional (3D) intestinal tissue model with the foodborne pathogen Campylobacter jejuni

Confocal microscopy image of a tissue-engineered 3D intestinal infection model cultured under dynamic conditions after four days of infection with C. jejuni wild-type strain 81-176. Bacteria (green, visualized with an anti-C. jejuni antibody) accumulate in a crypt-like structure of the 3D tissue model. Nuclei were stained with DAPI (blue), and adherens junctions were imaged using an anti-E-cadherin antibody (magenta). Alzheimer et al.

Image Credit: Mona Alzheimer and Cynthia M. Sharma. (2020)

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Colonization of a three-dimensional (3D) intestinal tissue model with the foodborne pathogen Campylobacter jejuni

Confocal microscopy image of a tissue-engineered 3D intestinal infection model cultured under dynamic conditions after four days of infection with C. jejuni wild-type strain 81-176. Bacteria (green, visualized with an anti-C. jejuni antibody) accumulate in a crypt-like structure of the 3D tissue model. Nuclei were stained with DAPI (blue), and adherens junctions were imaged using an anti-E-cadherin antibody (magenta). Alzheimer et al.

Image Credit: Mona Alzheimer and Cynthia M. Sharma. (2020)

https://doi.org/10.1371/image.ppat.v16.i02.g001