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PLoS Pathogens Issue Image | Vol. 9(11) November 2013

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Involvement of the cellular phosphatase DUSP1 in vaccinia virus infection.

The mouse host cell restricted attenuated vaccinia virus MVA is able to replicate and produce mature virions (green dots) in murine embryo fibroblasts (MEFs) lacking the cellular dual phosphatase DUSP1, involved in MAPK signaling pathway. See Cáceres et al.

Image Credit: Ana Cáceres, Beatriz Perdiguero, Carmen E. Gómez, Maria Victoria Cepeda, Carme Caelles, Carlos Oscar Sorzano, and Mariano Esteban (Centro Nacional de Biotecnología, CSIC and University of Barcelona, Spain).

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Involvement of the cellular phosphatase DUSP1 in vaccinia virus infection.

The mouse host cell restricted attenuated vaccinia virus MVA is able to replicate and produce mature virions (green dots) in murine embryo fibroblasts (MEFs) lacking the cellular dual phosphatase DUSP1, involved in MAPK signaling pathway. See Cáceres et al.

Image Credit: Ana Cáceres, Beatriz Perdiguero, Carmen E. Gómez, Maria Victoria Cepeda, Carme Caelles, Carlos Oscar Sorzano, and Mariano Esteban (Centro Nacional de Biotecnología, CSIC and University of Barcelona, Spain).

https://doi.org/10.1371/image.ppat.v09.i11.g001