Figures
An intimate relationship.
Chlamydia trachomatis is the leading cause of the preventable blindness trachoma worldwide and a major cause of sexually transmitted disease in developed countries. Hidden within the confines of an intracellular niche (shown), the bacterium wields its armament of defense, evasion, and procurement strategies. Rejman Lipinski et al. reveal another snippet of the Chlamydia–host cross-talk, demonstrating that distinct host Rab proteins are essential for the stability of the Golgi apparatus, a key host organelle intimately linked with infection outcome. Such insights will hopefully further broaden the options for the development of novel anti-chlamydial treatments (see Rejman Lipinski et al., doi:10.1371/journal.ppat.1000615).
Image Credit: Volker Brinkmann, Max Planck Institute for Infection Biology
Citation: (2009) PLoS Pathogens Issue Image | Vol. 5(10) October 2009. PLoS Pathog 5(10): ev05.i10. https://doi.org/10.1371/image.ppat.v05.i10
Published: October 30, 2009
Copyright: © 2009 Volker Brinkmann. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Chlamydia trachomatis is the leading cause of the preventable blindness trachoma worldwide and a major cause of sexually transmitted disease in developed countries. Hidden within the confines of an intracellular niche (shown), the bacterium wields its armament of defense, evasion, and procurement strategies. Rejman Lipinski et al. reveal another snippet of the Chlamydia–host cross-talk, demonstrating that distinct host Rab proteins are essential for the stability of the Golgi apparatus, a key host organelle intimately linked with infection outcome. Such insights will hopefully further broaden the options for the development of novel anti-chlamydial treatments (see Rejman Lipinski et al., doi:10.1371/journal.ppat.1000615).
Image Credit: Volker Brinkmann, Max Planck Institute for Infection Biology