Figures
The ciliated cells of an in vitro model of human airway epithelium.
The ciliated airway epithelium is the target for influenza virus infection in the human host. Ciliated cells in an in vitro model of human airway epithelium (HAE) are shown here, detected by immunostaining with anti-βIV tubulin primary and Texas red secondary antibodies and visualized using confocal microscopy. This in vitro model facilitates detailed characterization of human influenza virus infection of the epithelium and allows identification of host restriction factors that limit infection of HAE by avian influenza viruses (see Scull et al., doi:10.1371/journal.ppat.1000424).
Image Credit: Raymond J. Pickles, University of North Carolina at Chapel Hill
Citation: (2009) PLoS Pathogens Issue Image | Vol. 5(5) May 2009. PLoS Pathog 5(5): ev05.i05. https://doi.org/10.1371/image.ppat.v05.i05
Published: May 29, 2009
Copyright: © 2009 Raymond J. Pickles. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The ciliated airway epithelium is the target for influenza virus infection in the human host. Ciliated cells in an in vitro model of human airway epithelium (HAE) are shown here, detected by immunostaining with anti-βIV tubulin primary and Texas red secondary antibodies and visualized using confocal microscopy. This in vitro model facilitates detailed characterization of human influenza virus infection of the epithelium and allows identification of host restriction factors that limit infection of HAE by avian influenza viruses (see Scull et al., doi:10.1371/journal.ppat.1000424).
Image Credit: Raymond J. Pickles, University of North Carolina at Chapel Hill