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PLoS Pathogens Issue Image | Vol. 3(8) August 2007

PLoS Pathogens Issue Image | Vol. 3(8) August 2007

PLOS
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SARS-CoV infection

Immunohistochemical analysis of lung tissue from a SARS-CoV-infected cynomolgus macaque stained for SARS-CoV (red) and phosphorylated STAT1 (brown). There is an abundance of phosphorylated STAT1 in the nuclei of alveolar cells, indicating the activation of innate immune responses. However, STAT1 is not activated in most SARS-CoV-infected cells (see de Lang et al, e112).

Image Credit: Photograph by L. Leijten, Erasmus MC.

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SARS-CoV infection

Immunohistochemical analysis of lung tissue from a SARS-CoV-infected cynomolgus macaque stained for SARS-CoV (red) and phosphorylated STAT1 (brown). There is an abundance of phosphorylated STAT1 in the nuclei of alveolar cells, indicating the activation of innate immune responses. However, STAT1 is not activated in most SARS-CoV-infected cells (see de Lang et al, e112).

Image Credit: Photograph by L. Leijten, Erasmus MC.

https://doi.org/10.1371/image.ppat.v03.i08.g001