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Open Access
Peer-reviewed
Research Article
Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury
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Fengming Huang ,
Contributed equally to this work with: Fengming Huang, Cong Zhang, Qiang Liu
Roles Conceptualization, Formal analysis, Validation, Visualization, Writing – review & editing
Affiliations Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Anhui, China, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Department of Biochemistry, School of Basic Medicine Peking Union Medical College, Beijing, China
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Cong Zhang ,
Contributed equally to this work with: Fengming Huang, Cong Zhang, Qiang Liu
Roles Formal analysis, Investigation, Validation, Visualization, Writing – original draft
Affiliations Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Anhui, China, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Department of Biochemistry, School of Basic Medicine Peking Union Medical College, Beijing, China
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Qiang Liu ,
Contributed equally to this work with: Fengming Huang, Cong Zhang, Qiang Liu
Roles Investigation
Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Department of Biochemistry, School of Basic Medicine Peking Union Medical College, Beijing, China
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Yan Zhao,
Roles Investigation, Supervision
Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Department of Biochemistry, School of Basic Medicine Peking Union Medical College, Beijing, China
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Yuqing Zhang,
Roles Investigation
Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Department of Biochemistry, School of Basic Medicine Peking Union Medical College, Beijing, China
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Yuhao Qin,
Roles Investigation
Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Department of Biochemistry, School of Basic Medicine Peking Union Medical College, Beijing, China
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Xiao Li,
Roles Validation
Affiliation Genetic Engineering Laboratory, Institute of Military Veterinary Medicine, Academy of Military Medical Sciences, Changchun, China
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Chang Li,
Roles Validation
Affiliation Genetic Engineering Laboratory, Institute of Military Veterinary Medicine, Academy of Military Medical Sciences, Changchun, China
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Congzhao Zhou ,
Roles Supervision
* E-mail: zcz@ustc.edu.cn (CZ); ningyik@126.com (NJ); jiang@pumc.edu.cn (CJ)
Affiliation Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Anhui, China
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Ningyi Jin ,
Roles Conceptualization, Resources
* E-mail: zcz@ustc.edu.cn (CZ); ningyik@126.com (NJ); jiang@pumc.edu.cn (CJ)
Affiliation Genetic Engineering Laboratory, Institute of Military Veterinary Medicine, Academy of Military Medical Sciences, Changchun, China
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Chengyu Jiang
Roles Conceptualization, Funding acquisition, Resources, Validation, Writing – original draft
* E-mail: zcz@ustc.edu.cn (CZ); ningyik@126.com (NJ); jiang@pumc.edu.cn (CJ)
Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Department of Biochemistry, School of Basic Medicine Peking Union Medical College, Beijing, China
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Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury
- Fengming Huang,
- Cong Zhang,
- Qiang Liu,
- Yan Zhao,
- Yuqing Zhang,
- Yuhao Qin,
- Xiao Li,
- Chang Li,
- Congzhao Zhou,
- Ningyi Jin
- Published: March 16, 2020
- https://doi.org/10.1371/journal.ppat.1008341