Table 1.
Definitions of model parameters for Equation 1.
Figure 1.
Phage decay in the culture medium in the absence of hosts.
The plot shows data from one of the three cultures in the phage decay experiment, with observed concentrations in log10 PFU mL−1 (points) and the fitted curve log10 V(t) = log10 V0−mt (line). The phage concentration declines linearly on log-linear axes, indicating approximately exponential decay with estimated rate 1.062×10−2 h−1.
Figure 2.
Binding of phages to bacterial hosts and the subsequent release of phage at lysis of infected cells.
The plot shows data from one of the three cultures in the binding assay, with observed concentrations of free phages in log10 PFU mL−1 (points) and the fitted curve V(t) (line), derived from Equation 1. Lysis of infected hosts is well synchronised at approximately 1.3 hours, although this is exaggerated by the fitted curve. The phage concentration does not appear to increase, which is consistent with the low estimate for the burst size (approximately equal to 2 virions).
Figure 3.
Data from interaction experiments together with fitted curves obtained by maximum likelihood estimation.
Concentrations of C. jejuni (circles; black) and phage (triangles; red) vary together in a way consistent with the threshold theory of phage-bacterial interactions. Fitted models in which parameters are either common to all (dashed) or allowed to vary between cultures (solid). Panels (A–H) correspond to cultures 1–8, respectively, with fitted parameters as given in Table 2 and Table 3.
Table 2.
Model parameters from Equation 1 where parameters are common to all cultures, fitted to data from the interaction experiments.
Table 3.
Model parameters from Equation 1 where parameters are allowed to vary between cultures, fitted to data from the interaction experiments.