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Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2

Fig 1

Density maps of the ACE2-bound and ACE2-free SARS-CoV spikes.

Surface shadowed diagrams of the ACE2-bound conformation 1, the ACE2-bound conformation 2, the ACE2-bound conformation 3, unbound-up and unbound-down conformations of the SARS-CoV S glycoprotein after trypsin cleavage and low pH treatment. One CTD1 is colored pink and the bound ACE2 is colored green. The angle between the long axes of the CTD1 and the horizontal plane is shown at the bottom of each conformation.

Fig 1

doi: https://doi.org/10.1371/journal.ppat.1007236.g001