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HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways

Fig 9

A schematic representation of the multiple mode of action of CpAMs on HBV capsid assembly and disassembly as well as their effects on cccDNA biosynthesis.

The red arrowed lines indicate the normal processes in viral replication. The black arrowed lines indicate CpAMs-induced processes. See text for detailed explanation.

Fig 9

doi: https://doi.org/10.1371/journal.ppat.1006658.g009