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Detecting Differential Transmissibilities That Affect the Size of Self-Limited Outbreaks

Figure 4

Comparing the transmissibility of primary and secondary cases for smallpox in Europe, 1958–1973.

The layout is analogous to Figure 2 except the axes distinguish between transmission of primary and secondary cases. The inset of panel A replicates the results when and are inferred separately (our preferred model), except that the y-axis is now the ratio of to . For panels B and C, the data is shown only for cases where there was a clear record of subsequent secondary infections (as opposed to knowing that four cases lead to ten secondary cases in aggregate). The 95% confidence intervals were found by parametric bootstrap on this more limited data set.

Figure 4

doi: https://doi.org/10.1371/journal.ppat.1004452.g004