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Chromobacterium Csp_P Reduces Malaria and Dengue Infection in Vector Mosquitoes and Has Entomopathogenic and In Vitro Anti-pathogen Activities

Figure 4

Csp_P elicits immune gene expression in the mosquito.

Induction of the Cec1 promoter in the SUA-5B cell-line exposed to P. putida and Chromobacterium sp. Csp_P. SUA-5B cells expressing a luciferase reporter gene driven by a Cec1 promoter were exposed to increasing concentrations of Csp_P and P. putida bacteria. Differences between bacteria-treated samples and PBS control samples were assessed by Dunnett's Multiple Comparison Test (**, p<0.01; ***, p<0.001).

Figure 4