Critical Role of IRF-5 in the Development of T helper 1 responses to Leishmania donovani infection
WT and Irf5-/- mice were infected with L. donovani amistigotes. At 5 h, splenic cDCs were purified. IL-12p35 mRNA was detected by real time PCR. Data is shown for n = 3 WT samples and n = 4 Irf5-/- samples.* denotes p<0.05 and ** denotes p<0.01.