Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection
Fig 5
Differential mRNA expression levels of selected proinflammatory cytokines and chemokines in brains of infected Ifit2-/- and WT mice.
RNA extracted from individual brain tissues of RSA59 infected WT and Ifit2-/- mice at day 3, 5, and 7 p.i. was analysed for mRNA levels of the indicated cytokines and chemokines by Real time PCR. Solid lines represent the mean levels of mRNA expression (n = 4–11). Asterix (*) represents differences that are statistically significant by Student’s unpaired t-test analysis (Mann-Whitney Test) (*P<0.05, **P<0.01, ***P<0.001).