Insights into the structural changes that trigger receptor binding upon proteolytic activation of Bacillus thuringiensis Vip3Aa insecticidal protein

Oscar Infante; Isabel Gómez; Angel E. Pélaez-Aguilar; Luis A. Verduzco-Rosas; Rosalina García-Suárez; Blanca I. García-Gómez; Zeyu Wang; Jie Zhang; Adan Guerrero; Alejandra Bravo; Mario Soberón

doi:10.1371/journal.ppat.1012765

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Open Access

Peer-reviewed

Research Article

Insights into the structural changes that trigger receptor binding upon proteolytic activation of Bacillus thuringiensis Vip3Aa insecticidal protein

Oscar Infante ,

Contributed equally to this work with: Oscar Infante, Isabel Gómez

Roles Data curation, Formal analysis

Affiliation Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Isabel Gómez ,

Contributed equally to this work with: Oscar Infante, Isabel Gómez

Roles Formal analysis, Investigation

Affiliation Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Angel E. Pélaez-Aguilar,

Roles Formal analysis, Investigation

Affiliation Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Luis A. Verduzco-Rosas,

Roles Formal analysis, Investigation

Affiliation Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Rosalina García-Suárez,

Roles Formal analysis, Investigation

Affiliation Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Blanca I. García-Gómez,

Roles Investigation

Affiliation Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Zeyu Wang,

Roles Formal analysis, Investigation

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China
⨯
Jie Zhang,

Roles Investigation, Resources

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China
⨯
Adan Guerrero,

Roles Formal analysis, Investigation

Affiliation Laboratorio Nacional de Microscopía Avanzada, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Alejandra Bravo,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Mario Soberón

Roles Conceptualization, Funding acquisition, Supervision

* E-mail: mario.soberon@ibt.unam.mx

Affiliation Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México

https://orcid.org/0000-0002-1593-9227

⨯

Insights into the structural changes that trigger receptor binding upon proteolytic activation of Bacillus thuringiensis Vip3Aa insecticidal protein

Oscar Infante,
Isabel Gómez,
Angel E. Pélaez-Aguilar,
Luis A. Verduzco-Rosas,
Rosalina García-Suárez,
Blanca I. García-Gómez,
Zeyu Wang,
Jie Zhang,
Adan Guerrero,
Alejandra Bravo

Published: December 5, 2024
https://doi.org/10.1371/journal.ppat.1012765

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Binding analysis
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