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Open Access
Peer-reviewed
Research Article
MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi
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Sajith Raghunandanan ,
Contributed equally to this work with: Sajith Raghunandanan, Kai Zhang, Yan Zhang, Raj Priya
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Kai Zhang ,
Contributed equally to this work with: Sajith Raghunandanan, Kai Zhang, Yan Zhang, Raj Priya
Roles Data curation, Methodology, Writing – review & editing
Affiliation Department of Oral Craniofacial Molecular Biology, School of Dentistry, Virginia Commonwealth University, Richmond, Virginia, United States of America
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Yan Zhang ,
Contributed equally to this work with: Sajith Raghunandanan, Kai Zhang, Yan Zhang, Raj Priya
Roles Data curation, Methodology
Affiliations Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Wenzhou Key Laboratory of Sanitary Microbiology, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China
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Raj Priya ,
Contributed equally to this work with: Sajith Raghunandanan, Kai Zhang, Yan Zhang, Raj Priya
Roles Formal analysis, Methodology
Affiliation Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Ching Wooen Sze,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Oral Craniofacial Molecular Biology, School of Dentistry, Virginia Commonwealth University, Richmond, Virginia, United States of America
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Yongliang Lou,
Roles Formal analysis, Software
Affiliation Wenzhou Key Laboratory of Sanitary Microbiology, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China
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Michael J. Lynch,
Roles Data curation, Formal analysis, Software, Validation, Writing – review & editing
Affiliation Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States of America
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Brian R. Crane,
Roles Data curation, Software, Validation, Writing – review & editing
Affiliation Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States of America
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Mark H. Kaplan,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliation Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Chunhao Li ,
Roles Data curation, Formal analysis, Investigation, Supervision, Writing – original draft, Writing – review & editing
* E-mail: cli5@vcu.edu (CL); xfyang@iu.edu (XFY)
Affiliation Department of Oral Craniofacial Molecular Biology, School of Dentistry, Virginia Commonwealth University, Richmond, Virginia, United States of America
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X. Frank Yang
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing
* E-mail: cli5@vcu.edu (CL); xfyang@iu.edu (XFY)
Affiliation Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi
- Sajith Raghunandanan,
- Kai Zhang,
- Yan Zhang,
- Raj Priya,
- Ching Wooen Sze,
- Yongliang Lou,
- Michael J. Lynch,
- Brian R. Crane,
- Mark H. Kaplan,
- Chunhao Li
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- Published: December 30, 2024
- https://doi.org/10.1371/journal.ppat.1012327