Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation

• Saima Rehman ,

  Contributed equally to this work with: Saima Rehman, Lubov S. Grigoryeva, Katherine H. Richardson

  Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Centre for Host-Microbiome Interactions, Dental Institute, King’s College London, London, United Kingdom

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• Lubov S. Grigoryeva ,

  Contributed equally to this work with: Saima Rehman, Lubov S. Grigoryeva, Katherine H. Richardson

  Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  http://orcid.org/0000-0002-9083-8805

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• Katherine H. Richardson ,

  Contributed equally to this work with: Saima Rehman, Lubov S. Grigoryeva, Katherine H. Richardson

  Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Chemistry and Biochemistry Department, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

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• Paula Corsini,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Host-Microbiome Interactions, Dental Institute, King’s College London, London, United Kingdom, Chemistry and Biochemistry Department, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

  http://orcid.org/0000-0002-4987-2235

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• Richard C. White,

  Roles Formal analysis, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  http://orcid.org/0000-0003-1970-692X

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• Rosie Shaw,

  Roles Investigation, Writing – review & editing

  Affiliation Chemistry and Biochemistry Department, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

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• Theo J. Portlock,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Host-Microbiome Interactions, Dental Institute, King’s College London, London, United Kingdom, Chemistry and Biochemistry Department, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

  http://orcid.org/0000-0001-5971-3847

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• Benjamin Dorgan,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Host-Microbiome Interactions, Dental Institute, King’s College London, London, United Kingdom, Chemistry and Biochemistry Department, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

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• Zeinab S. Zanjani,

  Roles Investigation, Writing – review & editing

  Affiliation Chemistry and Biochemistry Department, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

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• Arianna Fornili,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Resources, Writing – original draft, Writing – review & editing

  Affiliation Chemistry and Biochemistry Department, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

  http://orcid.org/0000-0001-6554-3979

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• Nicholas P. Cianciotto ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: n-cianciotto@northwestern.edu (NPC); james.garnett@kcl.ac.uk (JAG)

  Affiliation Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  http://orcid.org/0000-0002-9572-8322

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• James A. Garnett

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: n-cianciotto@northwestern.edu (NPC); james.garnett@kcl.ac.uk (JAG)

  Affiliations Centre for Host-Microbiome Interactions, Dental Institute, King’s College London, London, United Kingdom, Chemistry and Biochemistry Department, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

  http://orcid.org/0000-0001-7621-8223

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