Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8⁺ T cell effector function

• Dallas Jones,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

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• Christina N. Como,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

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• Lichen Jing,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America

  http://orcid.org/0000-0002-5938-4171

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• Anna Blackmon,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

  http://orcid.org/0000-0002-4806-1326

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• Charles Preston Neff,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Department of Medicine, Division of Allergy and Clinical Immunology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

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• Owen Krueger,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Medicine, Division of Allergy and Clinical Immunology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

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• Andrew N. Bubak,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

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• Brent E. Palmer,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Medicine, Division of Allergy and Clinical Immunology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

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• David M. Koelle,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliations Department of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Laboratory Medicine, University of Washington, Seattle, Washington, United States of America, Department of Global Health, University of Washington, Seattle, Washington, United States of America, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America, Benaroya Research Institute, Seattle, Washington, United States of America, Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

  http://orcid.org/0000-0003-1255-9023

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• Maria A. Nagel

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: maria.nagel@ucdenver.edu

  Affiliations Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, United States of America, Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

  http://orcid.org/0000-0003-0549-812X

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