A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine

• Nicholas C. Wu,

  Roles Conceptualization, Formal analysis, Investigation, Software, Writing – original draft, Writing – review & editing

  Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States of America

  http://orcid.org/0000-0002-9078-6697

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• Seth J. Zost,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Microbiology, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, United States of America

  http://orcid.org/0000-0001-6712-5076

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• Andrew J. Thompson,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States of America

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• David Oyen,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States of America

  http://orcid.org/0000-0002-4324-9688

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• Corwin M. Nycholat,

  Roles Resources

  Affiliation Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States of America

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• Ryan McBride,

  Roles Resources

  Affiliation Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States of America

  http://orcid.org/0000-0001-8616-1910

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• James C. Paulson,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliations Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States of America, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, United States of America

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• Scott E. Hensley,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Department of Microbiology, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, United States of America

  http://orcid.org/0000-0002-2928-7506

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• Ian A. Wilson

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: wilson@scripps.edu

  Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, United States of America

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