Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype

Antonio V. Bordería; Ofer Isakov; Gonzalo Moratorio; Rasmus Henningsson; Sonia Agüera-González; Lindsey Organtini; Nina F. Gnädig; Hervé Blanc; Andrés Alcover; Susan Hafenstein; Magnus Fontes; Noam Shomron; Marco Vignuzzi

doi:10.1371/journal.ppat.1004838

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Peer-reviewed

Research Article

Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype

Antonio V. Bordería,

Affiliations Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France, Institut Pasteur, International Group for Data Analysis, Paris, France
⨯
Ofer Isakov ,

Contributed equally to this work with: Ofer Isakov, Gonzalo Moratorio

Affiliation Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Gonzalo Moratorio ,

Contributed equally to this work with: Ofer Isakov, Gonzalo Moratorio

Affiliation Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France
⨯
Rasmus Henningsson,

Affiliations Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France, Institut Pasteur, International Group for Data Analysis, Paris, France, Centre for Mathematical Sciences, Lund University, Lund, Sweden
⨯
Sonia Agüera-González,

Affiliation Institut Pasteur, Lymphocyte Cell Biology Unit, CNRS URA 1960, Paris, France
⨯
Lindsey Organtini,

Affiliation Division of Infectious Diseases, Pennsylvania State College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Nina F. Gnädig,

Affiliation Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France
⨯
Hervé Blanc,

Affiliation Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France
⨯
Andrés Alcover,

Affiliation Institut Pasteur, Lymphocyte Cell Biology Unit, CNRS URA 1960, Paris, France
⨯
Susan Hafenstein,

Affiliation Division of Infectious Diseases, Pennsylvania State College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Magnus Fontes,

Affiliations Institut Pasteur, International Group for Data Analysis, Paris, France, Centre for Mathematical Sciences, Lund University, Lund, Sweden
⨯
Noam Shomron,

Affiliation Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Marco Vignuzzi

* E-mail: marco.vignuzzi@pasteur.fr

Affiliation Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France
⨯

Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype

Antonio V. Bordería,
Ofer Isakov,
Gonzalo Moratorio,
Rasmus Henningsson,
Sonia Agüera-González,
Lindsey Organtini,
Nina F. Gnädig,
Hervé Blanc,
Andrés Alcover,
Susan Hafenstein

Published: May 5, 2015
https://doi.org/10.1371/journal.ppat.1004838

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