Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

Fernanda O. Novais; Lucas P. Carvalho; Joel W. Graff; Daniel P. Beiting; Gordon Ruthel; David S. Roos; Michael R. Betts; Michael H. Goldschmidt; Mary E. Wilson; Camila I. de Oliveira; Phillip Scott

doi:10.1371/journal.ppat.1003504

Loading metrics

Open Access

Peer-reviewed

Research Article

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

Fernanda O. Novais,

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Lucas P. Carvalho,

Affiliation Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais-INCT-DT(CNPq/MCT), Serviço de Imunologia, Hospital Universitario Prof. Edgard Santos, Universidade Federal da Bahia Salvador, Bahia, Brazil
⨯
Joel W. Graff,

Affiliation Iowa City VA Medical Center, Iowa City, Iowa, United States of America
⨯
Daniel P. Beiting,

Affiliation Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Gordon Ruthel,

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
David S. Roos,

Affiliation Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Michael R. Betts,

Affiliation Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Michael H. Goldschmidt,

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Mary E. Wilson,

Affiliation Iowa City VA Medical Center, Iowa City, Iowa, United States of America
⨯
Camila I. de Oliveira,

Affiliation Centro de Pesquisas Gonçalo Moniz, Fundaçao Oswaldo Cruz, Salvador, Brazil
⨯
Phillip Scott

* E-mail: pscott@vet.upenn.edu

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

Fernanda O. Novais,
Lucas P. Carvalho,
Joel W. Graff,
Daniel P. Beiting,
Gordon Ruthel,
David S. Roos,
Michael R. Betts,
Michael H. Goldschmidt,
Mary E. Wilson,
Camila I. de Oliveira

Published: July 18, 2013
https://doi.org/10.1371/journal.ppat.1003504

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Parasitic diseases
Is the Subject Area "Parasitic diseases" applicable to this article?

Thanks for your feedback.
Ear infections
Is the Subject Area "Ear infections" applicable to this article?

Thanks for your feedback.
Cytopathology
Is the Subject Area "Cytopathology" applicable to this article?

Thanks for your feedback.
Lesions
Is the Subject Area "Lesions" applicable to this article?

Thanks for your feedback.
Leishmaniasis
Is the Subject Area "Leishmaniasis" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.