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Open Access
Peer-reviewed
Research Article
A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins
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Anthony Ryan,
Affiliation Immunomodulation Research Group, School of Biotechnology, Dublin City University, Ireland
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Mark Lynch,
Affiliation Immunomodulation Research Group, School of Biotechnology, Dublin City University, Ireland
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Sinead M. Smith,
Affiliation Department of Clinical Medicine and Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St James's Hospital, Dublin, Ireland
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Sylvie Amu,
Affiliation Department of Clinical Medicine and Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St James's Hospital, Dublin, Ireland
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Hendrik J. Nel,
Affiliation Department of Clinical Medicine and Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St James's Hospital, Dublin, Ireland
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Claire E. McCoy,
Affiliation School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
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Jennifer K. Dowling,
Affiliation Immunomodulation Research Group, School of Biotechnology, Dublin City University, Ireland
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Eve Draper,
Affiliation Immunomodulation Research Group, School of Biotechnology, Dublin City University, Ireland
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Vincent O'Reilly,
Affiliation Immunomodulation Research Group, School of Biotechnology, Dublin City University, Ireland
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Ciara McCarthy,
Affiliation Immunomodulation Research Group, School of Biotechnology, Dublin City University, Ireland
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Julie O'Brien,
Affiliation Department of Clinical Medicine and Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St James's Hospital, Dublin, Ireland
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Déirdre Ní Eidhin,
Affiliation Department of Clinical Medicine and Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St James's Hospital, Dublin, Ireland
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Mary J. O'Connell,
Affiliation Molecular Evolution Group, School of Biotechnology, Dublin City University, Ireland
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Brian Keogh,
Affiliation Department of Clinical Medicine and Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St James's Hospital, Dublin, Ireland
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Charles O. Morton,
Affiliation Department of Clinical Microbiology, St James Hospital, Trinity College, Dublin, Ireland
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Thomas R. Rogers,
Affiliation Department of Clinical Microbiology, St James Hospital, Trinity College, Dublin, Ireland
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Padraic G. Fallon,
Affiliation Department of Clinical Medicine and Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St James's Hospital, Dublin, Ireland
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Luke A. O'Neill,
Affiliation School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
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Dermot Kelleher ,
Contributed equally to this work with: Dermot Kelleher, Christine E. Loscher
Affiliation Department of Clinical Medicine and Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St James's Hospital, Dublin, Ireland
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Christine E. Loscher
Contributed equally to this work with: Dermot Kelleher, Christine E. Loscher
* E-mail: Christine.loscher@dcu.ie
Affiliation Immunomodulation Research Group, School of Biotechnology, Dublin City University, Ireland
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A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins
- Anthony Ryan,
- Mark Lynch,
- Sinead M. Smith,
- Sylvie Amu,
- Hendrik J. Nel,
- Claire E. McCoy,
- Jennifer K. Dowling,
- Eve Draper,
- Vincent O'Reilly,
- Ciara McCarthy
- Published: June 30, 2011
- https://doi.org/10.1371/journal.ppat.1002076