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Open Access
Peer-reviewed
Research Article
Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection
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Guido Ferrari ,
Contributed equally to this work with: Guido Ferrari, Bette Korber
* E-mail: gflmp@duke.edu
Affiliation Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America
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Bette Korber ,
Contributed equally to this work with: Guido Ferrari, Bette Korber
Affiliation Los Alamos National Laboratory, Theoretical Division, Los Alamos, New Mexico, United States of America
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Nilu Goonetilleke,
Affiliation University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom
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Michael K. P. Liu,
Affiliation University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom
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Emma L. Turnbull,
Affiliation Nuffield Department of Clinical Medicine, University of Oxford, The Jenner Institute, Newbury, United Kingdom
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Jesus F. Salazar-Gonzalez,
Affiliation Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
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Natalie Hawkins,
Affiliation VID Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Steve Self,
Affiliation VID Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Sydeaka Watson,
Affiliations Los Alamos National Laboratory, Theoretical Division, Los Alamos, New Mexico, United States of America, Departmental of Statistical Sciences, Baylor University, Waco, Texas, United States of America
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Michael R. Betts,
Affiliation Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Cynthia Gay,
Affiliation Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Kara McGhee,
Affiliation Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
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Pierre Pellegrino,
Affiliation Centre for Sexual Health & HIV Research, Mortimer Market Centre, London, United Kingdom
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Ian Williams,
Affiliation Centre for Sexual Health & HIV Research, Mortimer Market Centre, London, United Kingdom
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Georgia D. Tomaras,
Affiliations Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America
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Barton F. Haynes,
Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America
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Clive M. Gray,
Affiliation AIDS Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
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Persephone Borrow,
Affiliation Nuffield Department of Clinical Medicine, University of Oxford, The Jenner Institute, Newbury, United Kingdom
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Mario Roederer,
Affiliation Vaccine Research Center, National Institute of Health, Bethesda, Maryland, United States of America
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Andrew J. McMichael,
Affiliation University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom
⨯ - [ ... ],
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Kent J. Weinhold
Affiliations Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America
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Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection
- Guido Ferrari,
- Bette Korber,
- Nilu Goonetilleke,
- Michael K. P. Liu,
- Emma L. Turnbull,
- Jesus F. Salazar-Gonzalez,
- Natalie Hawkins,
- Steve Self,
- Sydeaka Watson,
- Michael R. Betts

- Published: February 10, 2011
- https://doi.org/10.1371/journal.ppat.1001273