Frequent Toggling between Alternative Amino Acids Is Driven by Selection in HIV-1

Open Access

Peer-reviewed

Research Article

Wayne Delport,

Affiliations Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, Cape Town, South Africa, Centre for High-Performance Computing, Rosebank, Cape Town, South Africa
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Konrad Scheffler,

Affiliation Computer Science Division, Department of Mathematical Sciences, University of Stellenbosch, Stellenbosch, South Africa
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Cathal Seoighe

* E-mail: cseoighe@gmail.com

Affiliations Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, Cape Town, South Africa, Centre for High-Performance Computing, Rosebank, Cape Town, South Africa
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Immune response
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HIV-1
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Phylogenetic analysis
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Natural selection
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Amino acid substitution
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Substitution mutation
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Viral evolution
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Biochemical simulations
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