About the Authors

Marion Gruffaz

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, United States of America

Tinghe Zhang

Roles Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing

Affiliation Department of Electrical and Computer Engineering, University of Texas at San Antonio, San Antonio, Texas, United States of America

Vickie Marshall

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Viral Oncology Section, AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

Priscila Gonçalves

Roles Data curation, Investigation, Methodology, Writing – review & editing

Current address: Center for Novel Cancer Therapies, Monter Cancer Center, Lake Success, New York, United States of America

Affiliation HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

Ramya Ramaswami

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

Nazzarena Labo

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Viral Oncology Section, AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

Denise Whitby

Roles Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing – review & editing

Affiliation Viral Oncology Section, AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

Thomas S. Uldrick

Roles Investigation, Supervision, Writing – review & editing

Affiliations HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Robert Yarchoan

Roles Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

Affiliation HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

Yufei Huang

Roles Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – review & editing

Affiliations Department of Electrical and Computer Engineering, University of Texas at San Antonio, San Antonio, Texas, United States of America, Department of Epidemiology and Biostatistics, The University of Texas Health San Antonio, San Antonio, Texas, United States of America

Shou-Jiang Gao

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

gaos8@upmc.edu

Affiliations Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, United States of America, UPMC Hillman Cancer Center, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Competing Interests

I have read the journal’s policy and the authors of this manuscript have the following competing interests: TSU and RY are co-inventors on a patent related to the treatment of KSHV-associated diseases with immune modulatory compounds, and the spouse of RY is a co-inventor on a patent related to the measurement of KSHV vIL-6. These inventions were all made as part of their duties as employees of the U.S. Government, and the patents are or will be assigned to U.S. Department of Health and Human Services. The government may convey a portion of the royalties it receives from licensure of its patents to its employee inventors. RY and TSU have a CRADA with Celgene Corp. and recently conducted clinical research using drugs supplied to the NCI by Merck and Co., Hoffman LaRoche, and Bayer Healthcare. TSU receives additional research funding from Roche. None of the other co-authors have conflicts of interest to disclose.