Co-opting ATP-generating glycolytic enzyme PGK1 phosphoglycerate kinase facilitates the assembly of viral replicase complexes

K. Reddisiva Prasanth; Chingkai Chuang; Peter D. Nagy

doi:10.1371/journal.ppat.1006689

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Peer-reviewed

Research Article

Co-opting ATP-generating glycolytic enzyme PGK1 phosphoglycerate kinase facilitates the assembly of viral replicase complexes

K. Reddisiva Prasanth ,

Contributed equally to this work with: K. Reddisiva Prasanth, Chingkai Chuang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

Affiliation Department of Plant Pathology, University of Kentucky, Plant Science Building, Lexington, KY, United States of America
⨯
Chingkai Chuang ,

Contributed equally to this work with: K. Reddisiva Prasanth, Chingkai Chuang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

Affiliation Department of Plant Pathology, University of Kentucky, Plant Science Building, Lexington, KY, United States of America
⨯
Peter D. Nagy

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: pdnagy2@uky.edu

Affiliation Department of Plant Pathology, University of Kentucky, Plant Science Building, Lexington, KY, United States of America

http://orcid.org/0000-0003-4164-1237

⨯

Co-opting ATP-generating glycolytic enzyme PGK1 phosphoglycerate kinase facilitates the assembly of viral replicase complexes

K. Reddisiva Prasanth,
Chingkai Chuang,
Peter D. Nagy

Published: October 23, 2017
https://doi.org/10.1371/journal.ppat.1006689

About the Authors

K. Reddisiva Prasanth

Contributed equally to this work with: K. Reddisiva Prasanth, Chingkai Chuang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

Affiliation Department of Plant Pathology, University of Kentucky, Plant Science Building, Lexington, KY, United States of America

Chingkai Chuang

Contributed equally to this work with: K. Reddisiva Prasanth, Chingkai Chuang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

Affiliation Department of Plant Pathology, University of Kentucky, Plant Science Building, Lexington, KY, United States of America

Peter D. Nagy

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: pdnagy2@uky.edu

Affiliation Department of Plant Pathology, University of Kentucky, Plant Science Building, Lexington, KY, United States of America

http://orcid.org/0000-0003-4164-1237

Competing Interests

The authors have declared that no competing interests exist.

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Yeast
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Viral replication
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Leaves
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Protein interactions
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Saccharomyces cerevisiae
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Northern blot
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RNA analysis
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Viral replication complex
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