Gene Editing Approaches against Viral Infections and Strategy to Prevent Occurrence of Viral Escape

Martyn K. White; Wenhui Hu; Kamel Khalili

doi:10.1371/journal.ppat.1005953

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Gene Editing Approaches against Viral Infections and Strategy to Prevent Occurrence of Viral Escape

Martyn K. White,

Affiliation Department of Neuroscience, Center for Neurovirology and Comprehensive NeuroAIDS Center, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States of America
⨯
Wenhui Hu,

Affiliation Department of Neuroscience, Center for Neurovirology and Comprehensive NeuroAIDS Center, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States of America
⨯
Kamel Khalili

* E-mail: kamel.khalili@temple.edu

Affiliation Department of Neuroscience, Center for Neurovirology and Comprehensive NeuroAIDS Center, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States of America
⨯

Gene Editing Approaches against Viral Infections and Strategy to Prevent Occurrence of Viral Escape

Martyn K. White,
Wenhui Hu,
Kamel Khalili

Published: December 8, 2016
https://doi.org/10.1371/journal.ppat.1005953

About the Authors

Martyn K. White

Affiliation Department of Neuroscience, Center for Neurovirology and Comprehensive NeuroAIDS Center, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States of America

Wenhui Hu

Kamel Khalili

* E-mail: kamel.khalili@temple.edu

Competing Interests

KK and WH are named on patents related to viral gene editing. KK is a cofounder and holds equity in Excision Biotherapeutics - a startup where he and WH serve as scientific advisors.

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HIV-1
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Guide RNA
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DNA recombination
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Non-homologous end joining
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RNA interference
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DNA repair
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Epstein-Barr virus
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Hepatitis B virus
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